NCT04590729

Brief Summary

The literature has shown that interrupting sitting time with frequent physical activities (e.g., cycling on a stationary bike for 3 minutes every 30 minutes of sitting) is effective for decreasing blood sugar levels. However, the optimal frequency and distribution of sitting interruption remains less clear. The purpose of this study is to compare the effects of two different protocols of sitting interruption (i.e., 3 minutes of cycling every 30 minutes versus 3 minutes of cycling every 15 minutes) on blood sugar levels.

Trial Health

87
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
11

participants targeted

Target at below P25 for not_applicable

Timeline
Completed

Started Oct 2020

Shorter than P25 for not_applicable

Geographic Reach
1 country

1 active site

Status
completed

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

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Study Timeline

Key milestones and dates

First Submitted

Initial submission to the registry

October 11, 2020

Completed
8 days until next milestone

First Posted

Study publicly available on registry

October 19, 2020

Completed
1 day until next milestone

Study Start

First participant enrolled

October 20, 2020

Completed
1 month until next milestone

Primary Completion

Last participant's last visit for primary outcome

November 20, 2020

Completed
Same day until next milestone

Study Completion

Last participant's last visit for all outcomes

November 20, 2020

Completed
Last Updated

November 24, 2020

Status Verified

November 1, 2020

Enrollment Period

1 month

First QC Date

October 11, 2020

Last Update Submit

November 21, 2020

Conditions

Outcome Measures

Primary Outcomes (1)

  • Postprandial glucose levels

    The investigators will measure capillary blood sugar levels every 30 minutes using the finger-stick method.

    three and a half hour after the carbohydrates intake

Study Arms (3)

3-min Exercise Per 30 Min

EXPERIMENTAL

This protocol involves 3 minutes of cycling on a stationary bike at moderate intensity every 30 minutes for 6 hours, totaling 36 minutes of cycling exercise.

Behavioral: 3-min Exercise Per 30 Min

3-min Exercise Per 15 Min

EXPERIMENTAL

This protocol involves 3 minutes of cycling on a stationary bike at moderate intensity every 15 minutes for 3 hours to match the total exercise duration in the first protocol.

Behavioral: 3-min Exercise Per 15 Min

Sitting

NO INTERVENTION

Sitting control.

Interventions

This protocol involves 3 minutes of cycling on a stationary bike at 50 revolutions per minute and 1 kilopond every 30 minutes for 6 hours, totaling 36 minutes of cycling exercise.

3-min Exercise Per 30 Min

This protocol involves 3 minutes of cycling on a stationary bike at 50 revolutions per minute and 1 kilopond every 15 minutes for 3 hours, totaling 36 minutes of cycling exercise.

3-min Exercise Per 15 Min

Eligibility Criteria

Age18 Years - 45 Years
Sexall
Healthy VolunteersYes
Age GroupsAdult (18-64)

You may qualify if:

  • Apparently healthy persons
  • Sedentary lifestyle

You may not qualify if:

  • Cardiovascular diseases
  • Pulmonary diseases
  • Metabolic diseases
  • Other contraindications to exercise

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

Franklin Pierce University

Rindge, New Hampshire, 03461, United States

Location

MeSH Terms

Conditions

Sedentary Behavior

Condition Hierarchy (Ancestors)

Behavior

Study Officials

  • Tongyu Ma, Ph.D.

    Franklin Pierce University

    PRINCIPAL INVESTIGATOR

Study Design

Study Type
interventional
Phase
not applicable
Allocation
RANDOMIZED
Masking
TRIPLE
Who Masked
PARTICIPANT, INVESTIGATOR, OUTCOMES ASSESSOR
Purpose
TREATMENT
Intervention Model
CROSSOVER
Model Details: three-by-three crossover design
Sponsor Type
OTHER
Responsible Party
PRINCIPAL INVESTIGATOR
PI Title
Assistant Professor of Health Sciences

Study Record Dates

First Submitted

October 11, 2020

First Posted

October 19, 2020

Study Start

October 20, 2020

Primary Completion

November 20, 2020

Study Completion

November 20, 2020

Last Updated

November 24, 2020

Record last verified: 2020-11

Data Sharing

IPD Sharing
Will not share

Locations