NCT04311983

Brief Summary

In a Hybrid Type 2 randomized trial, 1,980 low-income smokers from nine states with high smoking prevalence will be recruited from 2-1-1 helplines to receive either current standard practice (Quitline) or expanded services (Quitline + Smoke Free Homes) to increase tobacco cessation.

Trial Health

87
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
1,973

participants targeted

Target at P75+ for not_applicable

Timeline
Completed

Started Mar 2020

Longer than P75 for not_applicable

Geographic Reach
1 country

1 active site

Status
completed

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

First Submitted

Initial submission to the registry

March 10, 2020

Completed
7 days until next milestone

First Posted

Study publicly available on registry

March 17, 2020

Completed
14 days until next milestone

Study Start

First participant enrolled

March 31, 2020

Completed
3.5 years until next milestone

Primary Completion

Last participant's last visit for primary outcome

September 29, 2023

Completed
Same day until next milestone

Study Completion

Last participant's last visit for all outcomes

September 29, 2023

Completed
1 year until next milestone

Results Posted

Study results publicly available

October 10, 2024

Completed
Last Updated

October 10, 2024

Status Verified

October 1, 2024

Enrollment Period

3.5 years

First QC Date

March 10, 2020

Results QC Date

September 11, 2024

Last Update Submit

October 8, 2024

Conditions

Outcome Measures

Primary Outcomes (1)

  • 7day Point Prevalence for Smoking

    Percentage of participants who have 7 day smoking abstinence

    6 month follow-up

Secondary Outcomes (1)

  • Proportion of Participants Who Accept the Tobacco Quitline Program

    Baseline and 3-month follow-up

Study Arms (2)

Tobacco Quitline only

ACTIVE COMPARATOR

Smokers in this study group will be offered their state Tobacco Quitline programs

Behavioral: Tobacco Quitline

Tobacco Quitline plus Smoke Free Homes

EXPERIMENTAL

Smokers in this study group will be offered their state Tobacco Quitline programs, but if they decline, they will be offered a Smoke Free Homes intervention

Behavioral: Tobacco QuitlineBehavioral: Smoke Free Home

Interventions

Tobacco quitlines provide phone counseling from a quit coach, often supplemented with NRT (nicotine replacement therapy), a quit guide, text messages, or other support. Smokers can call directly or consent to be called by the quitline ("fax-back").

Tobacco Quitline onlyTobacco Quitline plus Smoke Free Homes
Smoke Free HomeBEHAVIORAL

The intervention guides participants though a 5-step process: (1) deciding to create a smoke-free home; (2) talking about it with household members; (3) setting a date for the home to become smoke-free; (4) making the home smoke-free; and (5) keeping the home smoke-free. Progress from one step to the next is facilitated over a 6-week period by three mailings sent to participants' homes and one telephone counseling call delivered by a trained smoke free homes coach.

Tobacco Quitline plus Smoke Free Homes

Eligibility Criteria

Age21 Years+
Sexall
Healthy VolunteersYes
Age GroupsAdult (18-64), Older Adult (65+)

You may qualify if:

  • Age ≥21
  • English-speaking
  • Daily smoker
  • Does not have a full home smoking ban
  • Recruited from those who called 2-1-1 for themselves and are not in acute crisis

You may not qualify if:

  • Pregnant women, because recommended tobacco cessation actions differ for this subset of smokers

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

Washington University School of Medicine

St Louis, Missouri, 63110, United States

Location

Related Publications (2)

  • McQueen A, Wolff J, Grimes L, Teshome E, Garg R, Thompson T, Carpenter K, Kegler MC, Kreuter MW. Comparing acceptance of smoking cessation and smoke-free home intervention offers and associated factors among people with low income in the USA: baseline results of a randomised controlled trial. BMJ Public Health. 2024 Apr 22;2(1):e000843. doi: 10.1136/bmjph-2023-000843. eCollection 2024 Jun.

  • Wolff JM, McQueen A, Garg R, Thompson T, Fu Q, Brown DS, Kegler M, Carpenter KM, Kreuter MW. Expanding population-level interventions to help more low-income smokers quit: Study protocol for a randomized controlled trial. Contemp Clin Trials. 2023 Jun;129:107202. doi: 10.1016/j.cct.2023.107202. Epub 2023 Apr 18.

Related Links

MeSH Terms

Conditions

Tobacco Use CessationSmoking

Condition Hierarchy (Ancestors)

Health BehaviorBehavior

Results Point of Contact

Title
Matthew Kreuter, Ph.D.
Organization
Washington University School of Medicine

Study Officials

  • Matthew Kreuter, Ph.D.

    Washington University School of Medicine

    PRINCIPAL INVESTIGATOR

Publication Agreements

PI is Sponsor Employee
Yes

Study Design

Study Type
interventional
Phase
not applicable
Allocation
RANDOMIZED
Masking
DOUBLE
Who Masked
PARTICIPANT, INVESTIGATOR
Masking Details
Participants are unaware of the arms and principal investigators are unaware of participant's randomization to study arm
Purpose
PREVENTION
Intervention Model
PARALLEL
Model Details: Two group intervention; standard care vs. standard + additional service
Sponsor Type
OTHER
Responsible Party
SPONSOR

Study Record Dates

First Submitted

March 10, 2020

First Posted

March 17, 2020

Study Start

March 31, 2020

Primary Completion

September 29, 2023

Study Completion

September 29, 2023

Last Updated

October 10, 2024

Results First Posted

October 10, 2024

Record last verified: 2024-10

Data Sharing

IPD Sharing
Will share

The HCRL Data Center will make the datasets and other materials available without cost to researchers and analysts after a data sharing agreement is completed. Consistent with NIH guidelines, the data sharing agreement: (1) records a request for data use and detailed description of the intent of use; (2) details the study's publication guidelines, including acknowledging and citing project personnel as appropriate; (3) ensures IRB compliance, including not using these data for non-research purposes; and (4) stipulates that users will not share or distribute the data to others without written permission.

Locations