NCT04291937

Brief Summary

This is an expanded access program in the USA to enable eligible patients with previously treated small cell lung cancer to access lurbinectedin treatment prior to FDA approval. Sites must apply to participate in the program. A medical doctor must assess whether the potential benefit outweighs the risk of the investigational therapy considering the program eligibility criteria and the individual patient's medical history.

Trial Health

Trial Relationships

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Study Timeline

Key milestones and dates

First Submitted

Initial submission to the registry

February 27, 2020

Completed
4 days until next milestone

First Posted

Study publicly available on registry

March 2, 2020

Completed
Last Updated

June 19, 2020

Status Verified

June 1, 2020

First QC Date

February 27, 2020

Last Update Submit

June 17, 2020

Conditions

Interventions

Powder for concentrate for solution for infusion in 4 mg vials

Also known as: PM01183

Eligibility Criteria

Age18 Years+
Sexall
Age GroupsAdult (18-64), Older Adult (65+)

You may qualify if:

  • Legally competent adult
  • Confirmed and unresectable Small Cell Lung Cancer (SCLC)
  • Patients must have received one prior chemotherapy containing line
  • Adequate organ, hematological, kidney, metabolic and liver function
  • Recovery from toxicities related to previous treatment(s)
  • Pregnancy must be excluded, medically acceptable contraception method

You may not qualify if:

  • Prior treatment with lurbinectedin
  • Certain concomitant diseases/conditions
  • Symptomatic, steroid-requiring or progressive CNS involvement.
  • Pregnant or breast-feeding women.

Contact the study team to confirm eligibility.

Sponsors & Collaborators

MeSH Terms

Conditions

Small Cell Lung Carcinoma

Interventions

PM 01183

Condition Hierarchy (Ancestors)

Carcinoma, BronchogenicBronchial NeoplasmsLung NeoplasmsRespiratory Tract NeoplasmsThoracic NeoplasmsNeoplasms by SiteNeoplasmsLung DiseasesRespiratory Tract Diseases

Study Design

Study Type
expanded access
Sponsor Type
INDUSTRY
Responsible Party
SPONSOR

Study Record Dates

First Submitted

February 27, 2020

First Posted

March 2, 2020

Last Updated

June 19, 2020

Record last verified: 2020-06