Key Insights

Highlights

Success Rate

73% trial completion

Published Results

75 trials with published results (20%)

Research Maturity

144 completed trials (38% of total)

Clinical Risk Assessment

Based on trial outcomes

Moderate Risk

Score: 49/100

Termination Rate

13.7%

52 terminated out of 380 trials

Success Rate

73.5%

-13.0% vs benchmark

Late-Stage Pipeline

11%

41 trials in Phase 3/4

Results Transparency

52%

75 of 144 completed with results

Key Signals

75 with results73% success52 terminated

Data Visualizations

Phase Distribution

339Total
Not Applicable (24)
Early P 1 (2)
P 1 (124)
P 2 (148)
P 3 (37)
P 4 (4)

Trial Status

Completed144
Unknown68
Recruiting57
Terminated52
Not Yet Recruiting27
Active Not Recruiting17

Trial Success Rate

73.5%

Benchmark: 86.5%

Based on 144 completed trials

Clinical Trials (380)

Showing 20 of 20 trials
NCT04553133Phase 2Active Not RecruitingPrimary

PF-07104091 as a Single Agent and in Combination Therapy

NCT07559929Phase 1Not Yet RecruitingPrimary

A Study of DXC006 With Immune Checkpoint Inhibitors or Platinum for Small Cell Lung CancerInhibitors or Platinum-Based Agents for Small Cell Lung Cancer.

NCT05337735Phase 2Suspended

A Phase II Clinical Trial to Evaluate Safety and Efficacy of XmAb20717 in Advanced Rare Cancers

NCT07557225Not ApplicableNot Yet Recruiting

18F-T2 PET/CT Imaging for CAIX Positive Solid Tumors

NCT02146170Recruiting

Tissue Procurement and Natural History Study of People With Non-Small Cell Lung Cancer, Small Cell Lung Cancer, Extrapulmonary Small Cell Cancer, Pulmonary Neuroendocrine Tumors, and Thymic Epithelial Tumors

NCT07124000Recruiting

DESTINY-PANTUMOUR04

NCT06117774Phase 3Active Not Recruiting

Study Evaluating Tarlatamab After Chemoradiotherapy in Limited-Stage Small-Cell Lung Cancer (LS-SCLC)

NCT05903092Phase 2RecruitingPrimary

MOnaliZumab in Combination With durvAlumab (MEDI4736) for tRreatmenT of Small Cell Lung Cancer

NCT07231445Phase 1RecruitingPrimary

Study of ZG006 in Combination With PD-1/PD-L1 Immune Checkpoint Inhibitors as First-Line Standard Therapy in Participants With Extensive Stage Small-Cell Lung Cancer

NCT07551635Phase 2Not Yet RecruitingPrimary

SMARCA4/2 Inhibitor for POU2F3-Positive SCLC

NCT07550049Not Yet RecruitingPrimary

Comprehensive Oncogenomic Mapping and Exploration in Thoracic and Head & Neck Oncology

NCT07177937Phase 1RecruitingPrimary

A Study of DXC014 in Patients With Advanced Solid Tumors.

NCT07547332Phase 2Not Yet RecruitingPrimary

Nab-Paclitaxel Combined With Local Therapy in Relapsed SCLC

NCT07402343Phase 2Not Yet RecruitingPrimary

Tarlatamab for SCLC Brain Metastases

NCT06898957Phase 1Active Not RecruitingPrimary

Study of Tarlatamab in Combination With YL201 With or Without Anti-programmed Death Ligand 1 (PD-L1) in Participants With Extensive Stage (ES) Small Cell Lung Cancer (SCLC)

NCT06257264Phase 1Recruiting

A Study to Examine the Safety of Different Doses of BG-68501 Given to Participants With Advanced-Stage Tumors

NCT06586957Phase 1Recruiting

A Study With NKT3964 for Adults With Advanced/Metastatic Solid Tumors

NCT06780137Phase 1RecruitingPrimary

A Study to Evaluate the Safety and Efficacy of Gocatamig (MK-6070) and Ifinatamab Deruxtecan (I-DXd) in Participants With Relapsed/Refractory Extensive-Stage Small Cell Lung Cancer (MK-6070-002)

NCT07476287Phase 2RecruitingPrimary

Symbiotic-Lung-14: A Study to Learn About the Study Medicine Called PF08634404 in Combination With Chemotherapy in Adult Participants With Transformed Small Cell Lung Cancer

NCT06500026Phase 3Active Not RecruitingPrimary

A Study Comparing BL-B01D1 With Topotecan in Patients With Recurrent Small Cell Lung Cancer(PANKU-Lung03)

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