Key Insights

Highlights

Success Rate

73% trial completion

Published Results

77 trials with published results (20%)

Research Maturity

145 completed trials (37% of total)

Clinical Risk Assessment

Based on trial outcomes

Moderate Risk

Score: 49/100

Termination Rate

13.9%

54 terminated out of 388 trials

Success Rate

72.9%

-13.7% vs benchmark

Late-Stage Pipeline

11%

42 trials in Phase 3/4

Results Transparency

53%

77 of 145 completed with results

Key Signals

77 with results73% success54 terminated

Data Visualizations

Phase Distribution

346Total
Not Applicable (24)
Early P 1 (2)
P 1 (128)
P 2 (150)
P 3 (38)
P 4 (4)

Trial Status

Completed145
Unknown67
Recruiting65
Terminated54
Not Yet Recruiting25
Active Not Recruiting17

Trial Success Rate

72.9%

Benchmark: 86.6%

Based on 145 completed trials

Clinical Trials (388)

Showing 20 of 20 trials
NCT04585750Phase 1Recruiting

The Evaluation of PC14586 in Patients With Advanced Solid Tumors Harboring a TP53 Y220C Mutation (PYNNACLE)

NCT07155174Phase 2RecruitingPrimary

A Study to Evaluate the Optimal Dose, Adverse Events and Change in Disease Activity of Intravenous ABBV-706 in Combination With Atezolizumab Versus Standard of Care as First-Line Treatment in Adult Participants With Previously Untreated Extensive Stage Small Cell Lung Cancer

NCT07509034Phase 1Recruiting

Autologous B7-H3 Chimeric Antigen Receptor T Cells in Previously Treated Extensive-Stage Small Cell Lung Cancer With Recurrent or Refractory Disease

NCT02146170Recruiting

Tissue Procurement and Natural History Study of People With Non-Small Cell Lung Cancer, Small Cell Lung Cancer, Extrapulmonary Small Cell Cancer, Pulmonary Neuroendocrine Tumors, and Thymic Epithelial Tumors

NCT06586957Phase 1Recruiting

A Study With NKT3964 for Adults With Advanced/Metastatic Solid Tumors

NCT03391362Not ApplicableActive Not Recruiting

Stereotactic Radiation in Patients With Small Cell Lung Cancer and 1-10 Brain Metastases

NCT07707895Phase 1Not Yet RecruitingPrimary

DAREON®-36: A Study to Test Obrixtamig in Combination With ZL-1310 in People With Advanced Small Cell Lung Cancer or Other Neuroendocrine Cancers

NCT01242072Phase 1Completed

Intravenous Palifosfamide-tris in Combination With Etoposide and Carboplatin in Patients With Malignancies

NCT07476287Phase 2RecruitingPrimary

Symbiotic-Lung-14: A Study to Learn About the Study Medicine Called PF08634404 in Combination With Chemotherapy in Adult Participants With Transformed Small Cell Lung Cancer

NCT07124000Recruiting

DESTINY-PANTUMOUR04

NCT06047379Phase 1Recruiting

Safety and Efficacy of NEO212 in Patients With Astrocytoma IDH-mutant, Glioblastoma IDH-wildtype or Brain Metastasis

NCT07559929Phase 1RecruitingPrimary

A Study of DXC006 With Immune Checkpoint Inhibitors or Platinum for Small Cell Lung Cancer.

NCT04624204Phase 3Active Not RecruitingPrimary

Placebo-controlled, Study of Concurrent Chemoradiation Therapy With Pembrolizumab Followed by Pembrolizumab and Olaparib in Newly Diagnosed Treatment-Naïve Limited-Stage Small Cell Lung Cancer (LS-SCLC) (MK 7339-013/KEYLYNK-013)

NCT07177937Phase 1RecruitingPrimary

A Study of DXC014 in Patients With Advanced Solid Tumors.

NCT07365241Phase 3RecruitingPrimary

A Study to Evaluate Adverse Events and Change in Disease Activity of Intravenous ABBV-706 Versus Standard of Care in Adult Participants With Relapsed/Refractory Small Cell Lung Cancer

NCT05983432Phase 1Recruiting

Evaluate BL-B01D1 in Patients With Metastatic or Unresectable Non-Small Cell Lung Cancer (NSCLC) and Other Solid Tumors

NCT07778316Phase 3RecruitingPrimary

Phase 3 Trial of Tarlatamab (SC vs IV) in Extensive-Stage Small Cell Lung Cancer After Platinum Based First-line Chemotherapy (ES-SCLC)

NCT06873555Phase 1Recruiting

A Study of DC05F01 in Chinese Patients With Recurrent/Refractory Ovarian Cancer and Other Advanced Solid Tumors

NCT06612151Phase 3Active Not RecruitingPrimary

A Phase III Study of YL201 in Relapsed Small Cell Lung Cancer (TAISHAN-302)

NCT04140526Phase 1Active Not Recruiting

Safety, PK and Efficacy of ONC-392 in Monotherapy and in Combination of Anti-PD-1 in Advanced Solid Tumors and NSCLC

Scroll to load more

Research Network

Activity Timeline