Success Metrics

Clinical Success Rate
71.4%

Based on 5 completed trials

Completion Rate
71%(5/7)
Active Trials
20(53%)
Results Posted
80%(4 trials)
Terminated
2(5%)

Phase Distribution

Ph phase_3
7
18%
Ph phase_1
18
47%
Ph phase_2
11
29%

Phase Distribution

18

Early Stage

11

Mid Stage

7

Late Stage

Phase Distribution36 total trials
Phase 1Safety & dosage
18(50.0%)
Phase 2Efficacy & side effects
11(30.6%)
Phase 3Large-scale testing
7(19.4%)

Highest Phase Reached

Phase 3

Trial Status & Enrollment

Completion Rate

50.0%

5 of 10 finished

Non-Completion Rate

50.0%

5 ended early

Currently Active

20

trials recruiting

Total Trials

38

all time

Status Distribution
Active(26)
Completed(5)
Terminated(5)
Other(2)

Detailed Status

Recruiting14
Not yet recruiting6
Active, not recruiting6
Completed5
Withdrawn3
Terminated2

Development Timeline

Analytics

Development Status

Total Trials
38
Active
20
Success Rate
71.4%
Most Advanced
Phase 3

Trials by Phase

Phase 118 (50.0%)
Phase 211 (30.6%)
Phase 37 (19.4%)

Trials by Status

withdrawn38%
not_yet_recruiting616%
recruiting1437%
active_not_recruiting616%
completed513%
terminated25%
unknown25%

Recent Activity

Clinical Trials (38)

Showing 20 of 38 trialsScroll for more
NCT07459634Phase 2

A Study of Lurbinectedin in Combination With Durvalumab for the Treatment of Participants With ES-SCLC

Not Yet Recruiting
NCT06088290Phase 3

Study of Lurbinectedin in Combination With Doxorubicin Versus Doxorubicin Alone as First-line Treatment in Participants With Metastatic Leiomyosarcoma (SaLuDo)

Recruiting
NCT07155174Phase 2

A Study to Evaluate the Optimal Dose, Adverse Events and Change in Disease Activity of Intravenous ABBV-706 in Combination With Atezolizumab Versus Standard of Care as First-Line Treatment in Adult Participants With Previously Untreated Extensive Stage Small Cell Lung Cancer

Recruiting
NCT05099666Phase 1

Lurbinectedin + Doxorubicin In Leiomyosarcoma

Active Not Recruiting
NCT05918640Phase 1

Lurbinectedin in FET-Fused Tumors

Recruiting
NCT04607954Phase 2

Durvalumab and Lurbinectedin for the Treatment of Relapsed or Refractory Small Cell Lung Cancer

Active Not Recruiting
NCT05578326Phase 2

Study of Trilaciclib and Lurbinectidin

Recruiting
NCT06228066Phase 2

Lurbinectedin With or Without Avelumab in Small Cell Carcinoma of the Bladder (LASER)

Recruiting
NCT04802174Phase 1

Lurbinectedin With Berzosertib, an ATR Kinase Inhibitor in Small Cell Cancers and High-Grade Neuroendocrine Cancers

Active Not Recruiting
NCT06681220Phase 1

Biomarker Directed Trial of Temozolomide and Stenoparib in Relapsed SCLC

Recruiting
NCT05091567Phase 3

A Phase III, Open-Label Study of Maintenance Lurbinectedin in Combination With Atezolizumab Compared With Atezolizumab in Participants With Extensive-Stage Small-Cell Lung Cancer

Active Not Recruiting
NCT05153239Phase 3

Clinical Trial of Lurbinectedin as Single-agent or in Combination With Irinotecan Versus Topotecan or Irinotecan in Patients With Relapsed Small-cell Lung Cancer (LAGOON)

Active Not Recruiting
NCT06203210Phase 3

A Study of Ifinatamab Deruxtecan Versus Treatment of Physician's Choice in Subjects With Relapsed Small Cell Lung Cancer

Recruiting
NCT05734066Phase 1

Study of Lurbinectedin Monotherapy in Pediatric and Young Adult Participants With Relapsed/Refractory Ewing Sarcoma

Recruiting
NCT07365241Phase 3

A Study to Evaluate Adverse Events and Change in Disease Activity of Intravenous ABBV-706 Versus Standard of Care in Adult Participants With Relapsed/Refractory Small Cell Lung Cancer

Not Yet Recruiting
NCT05636111Phase 1

Phase 1b of Lurbinectedin in Combination With Weekly Paclitaxel and Bevacizumab in Platinum-resistant Ovarian Cancer

Recruiting
NCT07328425Phase 2

Clinical Study in Patients With DSRCT

Recruiting
NCT05740566Phase 3

Study Comparing Tarlatamab With Standard of Care Chemotherapy in Relapsed Small Cell Lung Cancer

Active Not Recruiting
NCT07153055Phase 1

Lurbinectedin With Osimertinib in Transformed Small Cell Lung Cancer

Not Yet Recruiting
NCT05244239Phase 1

Palliative Radiotherapy With Lurbinectedin in Patients With Extensive Stage Small Cell Lung Cancer

Recruiting

Drug Details

Intervention Type
DRUG
Total Trials
38