Success Metrics

Clinical Success Rate
75.0%

Based on 6 completed trials

Completion Rate
75%(6/8)
Active Trials
25(63%)
Results Posted
67%(4 trials)
Terminated
2(5%)

Phase Distribution

Ph phase_1
19
48%
Ph phase_2
12
30%
Ph phase_3
7
18%

Phase Distribution

19

Early Stage

12

Mid Stage

7

Late Stage

Phase Distribution38 total trials
Phase 1Safety & dosage
19(50.0%)
Phase 2Efficacy & side effects
12(31.6%)
Phase 3Large-scale testing
7(18.4%)

Highest Phase Reached

Phase 3

Trial Status & Enrollment

Completion Rate

54.5%

6 of 11 finished

Non-Completion Rate

45.5%

5 ended early

Currently Active

25

trials recruiting

Total Trials

40

all time

Status Distribution
Active(27)
Completed(6)
Terminated(5)
Other(2)

Detailed Status

Recruiting18
Active, not recruiting7
Completed6
Withdrawn3
unknown2
Terminated2

Development Timeline

Analytics

Development Status

Total Trials
40
Active
25
Success Rate
75.0%
Most Advanced
Phase 3

Trials by Phase

Phase 119 (50.0%)
Phase 212 (31.6%)
Phase 37 (18.4%)

Trials by Status

active_not_recruiting718%
recruiting1845%
completed615%
unknown25%
terminated25%
withdrawn38%
not_yet_recruiting25%

Recent Activity

Clinical Trials (40)

Showing 20 of 40 trialsScroll for more
NCT07155174Phase 2

A Study to Evaluate the Optimal Dose, Adverse Events and Change in Disease Activity of Intravenous ABBV-706 in Combination With Atezolizumab Versus Standard of Care as First-Line Treatment in Adult Participants With Previously Untreated Extensive Stage Small Cell Lung Cancer

Recruiting
NCT07365241Phase 3

A Study to Evaluate Adverse Events and Change in Disease Activity of Intravenous ABBV-706 Versus Standard of Care in Adult Participants With Relapsed/Refractory Small Cell Lung Cancer

Recruiting
NCT05153239Phase 3

Clinical Trial of Lurbinectedin as Single-agent or in Combination With Irinotecan Versus Topotecan or Irinotecan in Patients With Relapsed Small-cell Lung Cancer (LAGOON)

Completed
NCT05578326Phase 2

Study of Trilaciclib and Lurbinectidin

Recruiting
NCT07459634Phase 2

A Study of Lurbinectedin in Combination With Durvalumab for the Treatment of Participants With ES-SCLC

Recruiting
NCT05091567Phase 3

A Phase III, Open-Label Study of Maintenance Lurbinectedin in Combination With Atezolizumab Compared With Atezolizumab in Participants With Extensive-Stage Small-Cell Lung Cancer

Active Not Recruiting
NCT07640932Phase 2

Lurbinectedin Plus Paclitaxel Versus Paclitaxel in Patients With Previously Treated Small Cell Lung Cancer

Not Yet Recruiting
NCT05918640Phase 1

Lurbinectedin in FET-Fused Tumors

Recruiting
NCT07328425Phase 2

Clinical Study in Adult and Young Adult Patients With Advanced Desmoplastic Small Round Cell Tumor (DSRCT) ISG-TULIPS

Recruiting
NCT05099666Phase 1

Lurbinectedin + Doxorubicin In Leiomyosarcoma

Active Not Recruiting
NCT05636111Phase 1

Phase 1b of Lurbinectedin in Combination With Weekly Paclitaxel and Bevacizumab in Platinum-resistant Ovarian Cancer

Recruiting
NCT06228066Phase 2

Lurbinectedin With or Without Avelumab in Small Cell Carcinoma of the Bladder (LASER)

Recruiting
NCT06203210Phase 3

A Study of Ifinatamab Deruxtecan Versus Treatment of Physician's Choice in Subjects With Relapsed Small Cell Lung Cancer

Recruiting
NCT05652686Phase 1

A Study of Peluntamig (PT217) in Patients With Neuroendocrine Carcinomas Expressing DLL3 (the SKYBRIDGE Study)

Recruiting
NCT06088290Phase 3

Study of Lurbinectedin in Combination With Doxorubicin Versus Doxorubicin Alone as First-line Treatment in Participants With Metastatic Leiomyosarcoma (SaLuDo)

Active Not Recruiting
NCT07153055Phase 1

Lurbinectedin With Osimertinib in Transformed Small Cell Lung Cancer

Recruiting
NCT06501976Phase 2

An Exploratory Study of Lurbinectedin With Radiotherapy in SCLC With Single-lesion Progression After First Course Treatment

Active Not Recruiting
NCT06497530Phase 2

Maintenance Lurbinectedin in Combination With Serplulimab for Patients With ES-SCLC

Recruiting
NCT05800587Phase 2

Dose Attenuated Chemotherapy in Compromised Patients With Lung Cancer

Recruiting
NCT04607954Phase 2

Durvalumab and Lurbinectedin for the Treatment of Relapsed or Refractory Small Cell Lung Cancer

Active Not Recruiting

Drug Details

Intervention Type
DRUG
Total Trials
40