Prevalence of Osteosarcopenic Obesity in Older Adults

NCT04288401 | Completed

• 1 other identifier: IstanbulMU3
• Study Type: observational
• Target: 460
• Locations: 1 country
• Sites: 1

Brief Summary

Osteosarcopenic Obesity (OSO) is a syndrome characterized by the loss of bone and muscle in addition to increase in the fat tissue as a result of aging process. It is the latest point of impairment in the bone,muscle and adipose tissue in older adults. OSO, as the name suggests, is the combination of three syndrome frequently encountered in the elderly: osteopenia/osteoporosis, sarcopenia and obesity. The aims of study are to determine the prevalence of OSO syndrome in community-dwelling adults of Turkey and determine the possible factors regarding risk of falling in this population

Conditions

Obesity; Sarcopenia; Osteopenia; Osteoporosis

Outcome Measures

Primary Outcomes (5)

• T score

  T scores of spine and femur neck examined with Dual X-Ray Absorptiometry. A T score\<-2,5 will be classified as osteoporosis while a T score between -1 and -2,5 will be counted as osteopenia

  1 hour

• Muscle Strength

  Measured by hand held dynamometer. The cut-off scores for man and woman are 27 kg and 16 kg, respectively

  5 minutes

• Muscle Mass

  Measured by bioimpedance analysis using Tanita TBF300. The cut-off scores for man and woman are 9,2 kg/m2 and 7,4 kg/m2, respectively

  2 minutes

• Muscle Performance

  Tested by 4 meter walk test. If the gait speed is lower than 0,8 m/s, the test is positive.

  3 minutes

• Obesity

  The fat percentage and the Body Mass Index measured by bioimpedance analysis using Tanita TBF300 is recorded. For BMI, 30 kg/m2 and over is classified as obesity whereas fat percentage of %35 and %28 (woman and man, respectively) and over was classified as obese.

  2 minutes

Secondary Outcomes (2)

• Comorbidity

  3 minutes

• History of falls

  1 minutes

Eligibility Criteria

• Age: 65 Years+
• Sex: all
• Healthy Volunteers: Yes
• Age Groups: Older Adult (65+)
• Sampling Method: Non-Probability Sample

Study Population

older adults at the age of 65 or over

You may qualify if:

• Age of 65 or over
• Being had been examined for all the primary outcome measures (i.e. the results of primary outcomes must be in the patient's file)

You may not qualify if:

• Severe cognitive dysfunction
• not being able to walk independently for 4 m

Sponsors & Collaborators

• Istanbul Medeniyet University: lead
• Goztepe Training and Research Hospital: collaborator

Study Sites (1)

Goztepe Training and Research Hospital

Istanbul, 34700, Turkey (Türkiye)

Location

Related Publications (1)

• Kolbasi EN, Demirdag F. Prevalence of osteosarcopenic obesity in community-dwelling older adults: a cross-sectional retrospective study. Arch Osteoporos. 2020 Oct 20;15(1):166. doi: 10.1007/s11657-020-00829-x.

  PMID: 33079259 DERIVED

MeSH Terms

Conditions

Obesity; Sarcopenia; Bone Diseases, Metabolic; Osteoporosis

Condition Hierarchy (Ancestors)

Overweight; Overnutrition; Nutrition Disorders; Nutritional and Metabolic Diseases; Body Weight; Signs and Symptoms; Pathological Conditions, Signs and Symptoms; Muscular Atrophy; Neuromuscular Manifestations; Neurologic Manifestations; Nervous System Diseases; Atrophy; Pathological Conditions, Anatomical; Bone Diseases; Musculoskeletal Diseases; Metabolic Diseases

Study Design

• Study Type: observational
• Observational Model: COHORT
• Time Perspective: RETROSPECTIVE
• Sponsor Type: OTHER
• Responsible Party: PRINCIPAL INVESTIGATOR
• PI Title: Principal Investigator

Study Record Dates

• First Submitted: February 26, 2020
• First Posted: February 28, 2020
• Study Start: February 25, 2020
• Primary Completion: March 31, 2020
• Study Completion: April 1, 2020
• Last Updated: May 19, 2020

Record last verified: 2020-05

Data Sharing

• IPD Sharing: Will not share

Locations

TU (1)