Preoperative Continuous Sciatic Perineural Analgesia in Patients Undergoing Lower Limb Revascularization

NCT04286971 | Completed DMC

• 1 other identifier: 25206319.3.0000.5279
• Study Type: observational
• Target: 15
• Locations: 1 country
• Sites: 1

Brief Summary

This study evaluates the pain score numerical rating, after sciatic analgesic continuous block, in patients with ischemic pain before surgery of limb revascularization. All patients received those blocks to control ischemic severe pain.

Conditions

Ischemic Leg; Peripheral Vascular Disease

Keywords

continuous peripheral block; sciatic block; ischemic pain

Outcome Measures

Primary Outcomes (1)

• change in numerical pain scale

  Numerical Pain Scale (END) self-assessed by the patient before and after 24 hours of continuous analgesic block of the sciatic nerve, with infusion of levobupivacaine 0,125% or ropivacaine 0,2%. The scale score is 0-10 (0= no pain; 10 = pain as bad as can be)

  24 hours after placement of sciatic catheter

Secondary Outcomes (3)

• change in numerical pain scale

  72 hours after placement of sciatic catheter

• classification of technique difficulties

  72 hours after placement of sciatic catheter

• classifications of possible complications

  72 hours after placement of sciatic catheter

Eligibility Criteria

• Sex: all
• Healthy Volunteers: No
• Age Groups: Child (0-17), Adult (18-64), Older Adult (65+)
• Sampling Method: Non-Probability Sample

Study Population

Patients with lower limb isquemic pain caused by peripheral arterial disease in the preoperative period.

You may qualify if:

• preoperative continuous sciatic-popliteal nerve block
• lower limb angioplasty
• peripheral arterial disease;
• between 2017 and 2018 years;
• correct filling of numerical rating pain evaluation in the medical record

You may not qualify if:

• peripheral block to treat another pathology or condition in te same patient;
• peripheral block at another concomitant site (other than the popliteal);
• No adequate record of the care received in the medical record
• if medical record is not available during the data collection period

Sponsors & Collaborators

• Hospital Municipal Miguel Couto: lead

Study Sites (1)

Rafael M Linhares

Rio de Janeiro, 22776050, Brazil

Location

Related Publications (9)

• Luiten WE, Schepers T, Luitse JS, Goslings JC, Hermanides J, Stevens MF, Hollmann MW, van Samkar G. Comparison of continuous nerve block versus patient-controlled analgesia for postoperative pain and outcome after talar and calcaneal fractures. Foot Ankle Int. 2014 Nov;35(11):1116-21. doi: 10.1177/1071100714546640. Epub 2014 Aug 12.

  PMID: 25116132 BACKGROUND

• Thomas K, Barrett B, Tupper R, Dacenko-Grawe L, Holm K. Pain management after total knee arthroplasty: a case-control study of continuous nerve block therapy. Orthop Nurs. 2014 Sep-Oct;33(5):268-76. doi: 10.1097/NOR.0b013e3182879bd9.

  PMID: 25362748 BACKGROUND

• Gelfand HJ, Ouanes JP, Lesley MR, Ko PS, Murphy JD, Sumida SM, Isaac GR, Kumar K, Wu CL. Analgesic efficacy of ultrasound-guided regional anesthesia: a meta-analysis. J Clin Anesth. 2011 Mar;23(2):90-6. doi: 10.1016/j.jclinane.2010.12.005.

  PMID: 21377070 BACKGROUND

• Compere V, Cornet C, Fourdrinier V, Maitre AM, Duparc F, Biga N, Dureuil B. [Evaluation of continuous nerve block for postoperative pain management in orthopaedic surgery]. Ann Fr Anesth Reanim. 2005 Jul;24(7):795-801. doi: 10.1016/j.annfar.2005.04.025. French.

  PMID: 15949910 BACKGROUND

• Aubuchon A, Arnold WD, Bracewell A, Hoyle JC. Sciatic neuropathy due to popliteal fossa nerve block. Muscle Nerve. 2017 Oct;56(4):822-824. doi: 10.1002/mus.25622. Epub 2017 Jun 6.

  PMID: 28214338 BACKGROUND

• Dingemans SA, de Ruiter KJ, Birnie MFN, Goslings JC, van Samkar G, Schepers T. Comparable Postoperative Pain Levels Using 2 Different Nerve Blocks in the Operative Treatment of Displaced Intra-articular Calcaneal Fractures. Foot Ankle Int. 2017 Dec;38(12):1352-1356. doi: 10.1177/1071100717730337. Epub 2017 Sep 16.

  PMID: 28918661 BACKGROUND

• Kim NY, Lee KY, Bai SJ, Hong JH, Lee J, Park JM, Kim SH. Comparison of the effects of remifentanil-based general anesthesia and popliteal nerve block on postoperative pain and hemodynamic stability in diabetic patients undergoing distal foot amputation: A retrospective observational study. Medicine (Baltimore). 2016 Jul;95(29):e4302. doi: 10.1097/MD.0000000000004302.

  PMID: 27442676 BACKGROUND

• Dao T, Amaro-Driedger D, Mehta J. Successful treatment of Raynaud's syndrome in a lupus patient with continuous bilateral popliteal sciatic nerve blocks: a case report. Local Reg Anesth. 2016 Jun 15;9:35-7. doi: 10.2147/LRA.S97111. eCollection 2016.

  PMID: 27366104 BACKGROUND

• Joshi G, Gandhi K, Shah N, Gadsden J, Corman SL. Peripheral nerve blocks in the management of postoperative pain: challenges and opportunities. J Clin Anesth. 2016 Dec;35:524-529. doi: 10.1016/j.jclinane.2016.08.041. Epub 2016 Oct 20.

  PMID: 27871587 RESULT

MeSH Terms

Conditions

Peripheral Vascular Diseases

Condition Hierarchy (Ancestors)

Vascular Diseases; Cardiovascular Diseases

Study Design

• Study Type: observational
• Observational Model: CASE ONLY
• Time Perspective: RETROSPECTIVE
• Sponsor Type: OTHER
• Responsible Party: PRINCIPAL INVESTIGATOR
• PI Title: Head of Anesthesiology and Pain Medicine Department

Study Record Dates

• First Submitted: February 25, 2020
• First Posted: February 27, 2020
• Study Start: February 19, 2020
• Primary Completion: April 30, 2020
• Study Completion: April 30, 2020
• Last Updated: May 19, 2020

Record last verified: 2020-05

Data Sharing

• IPD Sharing: Will not share

Locations

BR (1)