NCT02935127

Brief Summary

Absorbable sutures are not generally accepted by the majority of vascular surgeons for the possible complications such as the breakage of the suture at the anastomoses level. Some experimental and clinical studies in the current literature demonstrated that the use of absorbable sutures may even reduce some important complications such as restenosis. The aim of this study is to compare absorbable and non-absorbable sutures in patients undergoing peripheral vascular surgery with vein bypass grafting.

Trial Health

35
At Risk

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Trial has exceeded expected completion date
Enrollment
100

participants targeted

Target at P50-P75 for not_applicable

Timeline
Completed

Started Nov 2016

Status
unknown

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

First Submitted

Initial submission to the registry

October 13, 2016

Completed
4 days until next milestone

First Posted

Study publicly available on registry

October 17, 2016

Completed
15 days until next milestone

Study Start

First participant enrolled

November 1, 2016

Completed
5 months until next milestone

Primary Completion

Last participant's last visit for primary outcome

April 1, 2017

Completed
1.1 years until next milestone

Study Completion

Last participant's last visit for all outcomes

May 1, 2018

Completed
Last Updated

October 17, 2016

Status Verified

October 1, 2016

Enrollment Period

5 months

First QC Date

October 13, 2016

Last Update Submit

October 13, 2016

Conditions

Keywords

absorbable sutures

Outcome Measures

Primary Outcomes (1)

  • Flow Velocity in the graft

    centimeters per second (cm/sec)

    18 months

Study Arms (2)

Absorbable Group

EXPERIMENTAL

In this group of patients absorbable sutures will be used for vascular anastomoses.

Procedure: Absorbable suture

Non-Absorbable Group

EXPERIMENTAL

In this group of patients non-absorbable sutures will be used for vascular anastomoses.

Procedure: Non-Absorbable suture

Interventions

Vascular anastomoses will be performed with absorbable materials

Absorbable Group

Vascular anastomoses will be performed with non-absorbable materials

Non-Absorbable Group

Eligibility Criteria

Age18 Years+
Sexall
Healthy VolunteersNo
Age GroupsAdult (18-64), Older Adult (65+)

You may qualify if:

  • Patients undergoing femoropopliteal or femorodistal vein bypass grafting;
  • Patients able to give informed consent;
  • Patients having no significant co-morbidity that makes life expectancy less than six months.

You may not qualify if:

  • patients that do not meet the aforementioned criteria.

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Related Publications (1)

  • Gasbarro V, Traina L, Mascoli F, Coscia V, Buffone G, Grande R, Fugetto F, Butrico L, de Franciscis S, Serra R. Absorbable suture material in carotid surgery. Vasa. 2015 Nov;44(6):451-7. doi: 10.1024/0301-1526/a000468.

    PMID: 26515222BACKGROUND

MeSH Terms

Conditions

Peripheral Vascular Diseases

Condition Hierarchy (Ancestors)

Vascular DiseasesCardiovascular Diseases

Study Officials

  • Raffaele Serra, M.D., PhD.

    University Magna Graecia of Catanzaro

    PRINCIPAL INVESTIGATOR
  • Stefano de Franciscis, M.D.

    University Magna Graecia of Catanzaro

    STUDY CHAIR

Central Study Contacts

Raffaele Raffaele, Raffaele

CONTACT

Study Design

Study Type
interventional
Phase
not applicable
Allocation
RANDOMIZED
Masking
NONE
Purpose
TREATMENT
Intervention Model
PARALLEL
Sponsor Type
OTHER
Responsible Party
PRINCIPAL INVESTIGATOR
PI Title
Professor

Study Record Dates

First Submitted

October 13, 2016

First Posted

October 17, 2016

Study Start

November 1, 2016

Primary Completion

April 1, 2017

Study Completion

May 1, 2018

Last Updated

October 17, 2016

Record last verified: 2016-10

Data Sharing

IPD Sharing
Will not share