D-OCT of Facial Telangiectasia Treated With IPL
Dynamic Optical Coherence Tomography Imaging of Telangiectasia Prior to Intense Pulsed Light Treatment - an Opportunity to Target Treatment?
1 other identifier
interventional
14
1 country
1
Brief Summary
Objectives: To examine whether dynamic Optical Coherence Tomography (OCT) could characterize vessel dimensions and blood flow of telangiectasias before and after treatment with Intense Pulsed Light (IPL). Methods: Dynamic-OCT (D-OCT) imaged telangiectasia characterized blood vessel width and depth, blood flow, and attenuation. Measurements were done immediately before and after, 1-3 days after, and 1 month after IPL treatment. Characterization of vessel dimensions at baseline were verified by a blinded observer. At one-month follow-up, clinical improvement was characterized as good, moderate or none and possible adverse effects were described.
Trial Health
Trial Health Score
Automated assessment based on enrollment pace, timeline, and geographic reach
participants targeted
Target at below P25 for not_applicable
Started Feb 2018
Shorter than P25 for not_applicable
1 active site
Health score is calculated from publicly available data and should be used for screening purposes only.
Trial Relationships
Click on a node to explore related trials.
Study Timeline
Key milestones and dates
Study Start
First participant enrolled
February 1, 2018
CompletedPrimary Completion
Last participant's last visit for primary outcome
October 1, 2018
CompletedStudy Completion
Last participant's last visit for all outcomes
October 1, 2018
CompletedFirst Submitted
Initial submission to the registry
February 15, 2020
CompletedFirst Posted
Study publicly available on registry
February 18, 2020
CompletedFebruary 18, 2020
February 1, 2020
8 months
February 15, 2020
February 15, 2020
Conditions
Keywords
Outcome Measures
Primary Outcomes (4)
vessel width dimension
measurement of vessel width on D-OCT images
one-month follow-up
vessel depth dimension
measurement of vessel depth on D-OCT images
one-month follow-up
vessel blood flow
measurement of vessel blood flow on D-OCT images
one-month follow-up
Attenuation
measurement of attenuation on D-OCT images
one-month follow-up
Other Outcomes (2)
Relation of D-OCT detected vessel dimensions to clinical efficacy
one-month follow-up
Relation of D-OCT detected vessel dimensions to adverse effects
one-month follow-up
Study Arms (1)
D-OCT image observational
OTHERPatients clinically eligible for IPL treatment of facial telangiectasia were D-OCT scanned before, after, 1-3 days after and 1 month after treatment
Interventions
observation by D-OCT before, after, 1-3 days after, and 1 month after IPL treatment
Eligibility Criteria
You may qualify if:
- legally competent,
- at least 18 years of age
- persons able to read and understand spoken and written information in Danish or English.
- One or more facial telangiectasia
You may not qualify if:
- wounds or ulcers in area of facial telangiectasia
Contact the study team to confirm eligibility.
Sponsors & Collaborators
Study Sites (1)
Zealand University Hospital Roskilde
Roskilde, 4000, Denmark
MeSH Terms
Conditions
Condition Hierarchy (Ancestors)
Study Officials
- PRINCIPAL INVESTIGATOR
Gregor BE Jemec, DmSc, Prof.
Zealand University Hospital - Roskilde
Study Design
- Study Type
- interventional
- Phase
- not applicable
- Allocation
- NA
- Masking
- NONE
- Purpose
- OTHER
- Intervention Model
- SINGLE GROUP
- Sponsor Type
- OTHER
- Responsible Party
- PRINCIPAL INVESTIGATOR
- PI Title
- Professor, PhD, DmsC, Head of Dpt.
Study Record Dates
First Submitted
February 15, 2020
First Posted
February 18, 2020
Study Start
February 1, 2018
Primary Completion
October 1, 2018
Study Completion
October 1, 2018
Last Updated
February 18, 2020
Record last verified: 2020-02
Data Sharing
- IPD Sharing
- Will not share