NCT05978986

Brief Summary

Purpose: To evaluate the sensitivity and specificity of the method for determining the clinical class of chronic venous diseases using the Ivenus application (within C0-C2 according to CEAP). Materials and methods: Patients who applied to several phlebology clinics for an initial consultation are consistently included in a multicenter prospective study. At the appointment, a doctor with at least 5 years of experience takes photographs of the lower extremities and uploads them to the IVENUS application, which automatically determines the clinical class according to CEAP, without showing the results to the surgeon (blinding). Further, the doctor independently determines the clinical class according to CEAP and enters the data into the register. The object of the study is a photograph of a certain area of the lower limb.

Trial Health

87
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
1,622

participants targeted

Target at P75+ for not_applicable

Timeline
Completed

Started Aug 2023

Typical duration for not_applicable

Geographic Reach
1 country

3 active sites

Status
completed

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

First Submitted

Initial submission to the registry

July 30, 2023

Completed
8 days until next milestone

First Posted

Study publicly available on registry

August 7, 2023

Completed
18 days until next milestone

Study Start

First participant enrolled

August 25, 2023

Completed
2.5 years until next milestone

Primary Completion

Last participant's last visit for primary outcome

February 23, 2026

Completed
Same day until next milestone

Study Completion

Last participant's last visit for all outcomes

February 23, 2026

Completed
Last Updated

March 6, 2026

Status Verified

March 1, 2026

Enrollment Period

2.5 years

First QC Date

July 30, 2023

Last Update Submit

March 4, 2026

Conditions

Outcome Measures

Primary Outcomes (1)

  • Determination of the sensitivity and specificity

    Determination of the sensitivity and specificity of the method for determining the clinical class of chronic venous diseases according to the CEAP classification using the IVENUS application (within C0-C2 classes).

    1 day

Secondary Outcomes (1)

  • Number of participants with complications

    1 day

Interventions

The doctor takes pictures of the lower extremities and uploads them to the IVENUS application, which automatically determines the clinical class according to CEAP. Further, the doctor independently determines the clinical class according to CEAP and enters the data into the register.

Eligibility Criteria

Sexall
Healthy VolunteersNo
Age GroupsChild (0-17), Adult (18-64), Older Adult (65+)

You may qualify if:

  • C0-C2 CEAP clinical class;
  • Signed consent to take part in investigation.

You may not qualify if:

  • C3-C6 CEAP clinical class;
  • Skin diseases of the lower extremities;
  • Immobilization.

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (3)

Phlebolog ltd.

Perm, Russia

Location

Azbuka zdoroviya ltd.

Yekaterinburg, Russia

Location

Vasculab ltd.

Yekaterinburg, Russia

Location

MeSH Terms

Conditions

Telangiectasis

Condition Hierarchy (Ancestors)

Vascular DiseasesCardiovascular Diseases

Study Officials

  • Denis Borsuk

    VenoClinica, "Vasculab" ltd.

    STUDY CHAIR

Study Design

Study Type
interventional
Phase
not applicable
Allocation
NA
Masking
DOUBLE
Who Masked
CARE PROVIDER, INVESTIGATOR
Purpose
SCREENING
Intervention Model
SINGLE GROUP
Sponsor Type
OTHER
Responsible Party
PRINCIPAL INVESTIGATOR
PI Title
Director

Study Record Dates

First Submitted

July 30, 2023

First Posted

August 7, 2023

Study Start

August 25, 2023

Primary Completion

February 23, 2026

Study Completion

February 23, 2026

Last Updated

March 6, 2026

Record last verified: 2026-03

Data Sharing

IPD Sharing
Will not share

Locations