NCT04273230

Brief Summary

Early detection of renal affection in patients with non alcaholic fatty liver diseases using microalbuminuria.

Trial Health

87
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
114

participants targeted

Target at P50-P75 for all trials

Timeline
Completed

Started Mar 2020

Geographic Reach
1 country

2 active sites

Status
completed

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

First Submitted

Initial submission to the registry

February 14, 2020

Completed
4 days until next milestone

First Posted

Study publicly available on registry

February 18, 2020

Completed
12 days until next milestone

Study Start

First participant enrolled

March 1, 2020

Completed
1 year until next milestone

Primary Completion

Last participant's last visit for primary outcome

March 1, 2021

Completed
3 months until next milestone

Study Completion

Last participant's last visit for all outcomes

June 1, 2021

Completed
Last Updated

February 23, 2022

Status Verified

February 1, 2020

Enrollment Period

1 year

First QC Date

February 14, 2020

Last Update Submit

February 7, 2022

Conditions

Outcome Measures

Primary Outcomes (1)

  • Early detection of kidney affection in non alcaholic fatty liver diseases

    Finding patients with non alcaholic fatty liver diseases who develop renal impairment

    Baseline

Interventions

Detection of microalbumin in urine

Eligibility Criteria

Age18 Years - 80 Years
Sexall
Age GroupsAdult (18-64), Older Adult (65+)
Sampling MethodNon-Probability Sample
Study Population

All pateints with fatty liver diseases diagnosed by ultrasonography and lab investigation

You may qualify if:

  • All patients with fatty liver disease diagnosed by abdominal ultrasonogarphy .
  • All patients with fatty liver disease diagnosed by lab investigations.

You may not qualify if:

  • Diabetic patients
  • Hypertensive patients
  • patients with chronic kidney disesase
  • patient with systemic diseases or chronic liver diseases affecting kidneys.

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (2)

Assiut university

Asyut, Egypt

Location

AssiutU

Asyut, Egypt

Location

Related Publications (3)

  • Arase Y, Suzuki F, Kobayashi M, Suzuki Y, Kawamura Y, Matsumoto N, Akuta N, Kobayashi M, Sezaki H, Saito S, Hosaka T, Ikeda K, Kumada H, Ohmoto Y, Amakawa K, Tsuji H, Hsieh SD, Kato K, Tanabe M, Ogawa K, Hara S, Kobayashi T. The development of chronic kidney disease in Japanese patients with non-alcoholic fatty liver disease. Intern Med. 2011;50(10):1081-7. doi: 10.2169/internalmedicine.50.5043. Epub 2011 May 1.

    PMID: 21576832BACKGROUND
  • Kiapidou S, Liava C, Kalogirou M, Akriviadis E, Sinakos E. Chronic kidney disease in patients with non-alcoholic fatty liver disease: What the Hepatologist should know? Ann Hepatol. 2020 Mar-Apr;19(2):134-144. doi: 10.1016/j.aohep.2019.07.013. Epub 2019 Sep 23.

    PMID: 31606352BACKGROUND
  • Park H, Dawwas GK, Liu X, Nguyen MH. Nonalcoholic fatty liver disease increases risk of incident advanced chronic kidney disease: a propensity-matched cohort study. J Intern Med. 2019 Dec;286(6):711-722. doi: 10.1111/joim.12964. Epub 2019 Aug 23.

    PMID: 31359543BACKGROUND

MeSH Terms

Conditions

Renal Insufficiency

Condition Hierarchy (Ancestors)

Kidney DiseasesUrologic DiseasesFemale Urogenital DiseasesFemale Urogenital Diseases and Pregnancy ComplicationsUrogenital DiseasesMale Urogenital Diseases

Study Design

Study Type
observational
Observational Model
OTHER
Time Perspective
CROSS SECTIONAL
Sponsor Type
OTHER
Responsible Party
PRINCIPAL INVESTIGATOR
PI Title
Doctor

Study Record Dates

First Submitted

February 14, 2020

First Posted

February 18, 2020

Study Start

March 1, 2020

Primary Completion

March 1, 2021

Study Completion

June 1, 2021

Last Updated

February 23, 2022

Record last verified: 2020-02

Locations