Renal Impairment
246
9
11
195
Key Insights
Highlights
Success Rate
90% trial completion (above average)
Published Results
48 trials with published results (20%)
Research Maturity
195 completed trials (79% of total)
Clinical Risk Assessment
Based on trial outcomes
Moderate Risk
Score: 50/100
8.5%
21 terminated out of 246 trials
90.3%
+3.8% vs benchmark
5%
12 trials in Phase 3/4
25%
48 of 195 completed with results
Key Signals
Data Visualizations
Phase Distribution
Trial Status
Trial Success Rate
Benchmark: 86.5%
Based on 195 completed trials
Clinical Trials (246)
Effect of Renal Impairment on Enpatoran Pharmacokinetics
A Study to Assess the Safety and Pharmacokinetics of INCB123667 When Administered Orally to Adult Participants With Severe Renal Impairment or End Stage Renal Disease
Pharmacokinetics of VC005 Tablets in Subjects With Renal Impairment and Normal Renal Function
A Study of Pharmacokinetics and Safety of LY3537031 in Participants With Normal Renal Function and Participants With Renal Impairment
Study of Bemnifosbuvir/Ruzasvir as a Fixed-dose Combination in Subjects With Normal or Severely Impaired Renal or Hepatic Function
A Clinical Trial of MK-2828 in People With Kidney Disease (MK-2828-006)
Groundbreaking Renal Assist Device Intervening to ENhance cardioThoracic Surgery Outcomes
A Study to Learn How the Body Processes the Study Medicine PF-07328948 in People With Reduced Kidney Function
Mannitol Versus Nitroglycerin for Kidney Injury Prevention in Robotic-assisted Radical Prostatectomy or Cystectomy
A Study of Eloralintide (LY3841136) in Participants With Renal Impairment and in Participants With Normal Renal Function
A Study to Test How BI 456906 is Taken up in the Blood of People With and Without Kidney Problems
Ultra-low Dose Contrast for Endovascular Procedures
Study of BPN14770 in Participants With Severe Renal Impairment and Healthy Controls
Investigation of the Effects of Renal Impairment on the Pharmacokinetics, Safety, and Tolerability of Opemalirsen (AZD2373)
A Study of MK-8527 in Participants With Moderate and Severe Renal Impairment (MK-8527-008)
A Clinical Study of Calderasib (MK-1084) in Participants With Renal Impairment (MK-1084-010)
Pharmacokinetics of Petrelintide Following Administration to Participants With Impaired Renal Function
Pharmacokinetics Study of MCI-186 in Subjects With Mild or Moderate Renal Impairment
An Investigational Study of ESK-001 in Participants With Normal Renal Function and Participants With Mild, Moderate, and Severe Impaired Renal Function
Assessment of Renal Function by Multiparametric MRI