Renal Impairment
247
8
9
199
Key Insights
Highlights
Success Rate
90% trial completion (above average)
Published Results
48 trials with published results (19%)
Research Maturity
199 completed trials (81% of total)
Clinical Risk Assessment
Based on trial outcomes
Moderate Risk
Score: 50/100
8.5%
21 terminated out of 247 trials
90.5%
+3.9% vs benchmark
5%
12 trials in Phase 3/4
24%
48 of 199 completed with results
Key Signals
Data Visualizations
Phase Distribution
Trial Status
Trial Success Rate
Benchmark: 86.5%
Based on 199 completed trials
Clinical Trials (247)
Study of Bemnifosbuvir/Ruzasvir as a Fixed-dose Combination in Subjects With Normal or Severely Impaired Renal or Hepatic Function
The Study is to Investigate D-2570 in Participants With Different Levels of Kidney Function.
A Clinical Trial of MK-2828 in People With Kidney Disease (MK-2828-006)
Single-Dose Study to Evaluate the PKs of Pretomanid in Participants With Renal Impairment Compared to Participants With Normal Renal Function
Pharmacokinetics Study of MCI-186 in Subjects With Mild or Moderate Renal Impairment
A Study of S-892216-PO in Participants With Renal Impairment and Matched Controls
Pharmacokinetics of VC005 Tablets in Subjects With Renal Impairment and Normal Renal Function
Pharmacokinetics and Safety Study of YZJ-1139 in Subjects With Severe Renal Impairment and Normal Renal Impairment
Pharmacokinetics and Safety Study of Levornidazole Disodium Phosphate for Injection in Subjects With Renal Impairment and Normal Renal Impairment
Investigation of the Effects of Renal Impairment on the Pharmacokinetics, Safety, and Tolerability of Opemalirsen (AZD2373)
A Study to Assess the Safety and Pharmacokinetics of INCB123667 When Administered Orally to Adult Participants With Severe Renal Impairment or End Stage Renal Disease
A Study to Learn How the Body Processes the Study Medicine PF-07328948 in People With Reduced Kidney Function
Effect of Renal Impairment on Enpatoran Pharmacokinetics
A Study of Pharmacokinetics and Safety of LY3537031 in Participants With Normal Renal Function and Participants With Renal Impairment
Groundbreaking Renal Assist Device Intervening to ENhance cardioThoracic Surgery Outcomes
Mannitol Versus Nitroglycerin for Kidney Injury Prevention in Robotic-assisted Radical Prostatectomy or Cystectomy
A Study of Eloralintide (LY3841136) in Participants With Renal Impairment and in Participants With Normal Renal Function
A Study to Test How BI 456906 is Taken up in the Blood of People With and Without Kidney Problems
Ultra-low Dose Contrast for Endovascular Procedures
Study of BPN14770 in Participants With Severe Renal Impairment and Healthy Controls