The Digital Memory Notebook

NCT04240665 | Enrolling By Invitation

• 1 other identifier: 1454000
• Study Type: interventional
• Target: 20
• Locations: 1 country
• Sites: 1

Brief Summary

Compensatory aids (e.g., alarms, calendars) play an important supporting role when completing everyday tasks (e.g., appointments, medication management), and there is a growing body of scientific work suggesting that compensatory training improves daily functioning. However, traditional paper-based calendars and to-do-lists have limitations related to accumulation of information, difficulty retrieving information, and remembering to complete activities. Such limitations may be overcome using a digital format through organized digital files, search functions, and alarms. This pilot project proposes to train older adults at risk for cognitive decline to use the Digital Memory Notebook (DMN), a tablet-based application (app), to support everyday functioning. The primary goal is to obtain preliminary evidence that a 6-week, individual and group-based DMN training intervention results in demonstrable changes in target behaviors (e.g., goal-directed DMN use to support everyday activities) among older adults with mild cognitive impairment (MCI) and subjective cognitive complaints (SCC). Participants will complete a curriculum involving 2-hour weekly sessions for 6-weeks. Each week will cover a specific function of the DMN and will include standardized goal-setting and weekly homework targets. Following the 6-week intervention, participants will continue to use the DMN app for 4-weeks to evaluate stability. Participants will complete a questionnaire packet 1 week prior to the 6-week intervention, 1 week after the 6-week intervention, and 5 weeks following the 6-week intervention. MCI and SCC participants will complete separate 6-week individual or group interventions spaced two months apart at UCD.

Conditions

Prodromal Alzheimer's Disease; Mild Cognitive Impairment; Subjective Cognitive Complaints

Outcome Measures

Primary Outcomes (1)

• Real-time data extracted from the DMN Application

  data that is automatically collected by DMN (Calendar entries, to-do list entries, alarms set, journal entries)

  Change in number of entries assessed weekly from first weekly session through Week 6 weekly session and for 4 weeks after the completion of the last session

Secondary Outcomes (1)

• Participant Questionnaire Outcomes

  Week 1, Week 8, and Week 12

Study Arms (1)

DMN Intervention

EXPERIMENTAL

Subjects will attend 2-hour weekly sessions for 6- weeks. Participants will continue to use the DMN application for 4-weeks after the intervention is complete.

Behavioral: Digital Memory Notebook (DMN) Application

Interventions

Digital Memory Notebook (DMN) Application BEHAVIORAL

Subjects will be taught to utilize the DMN application through 2-hour weekly sessions for 6-weeks.

DMN Intervention

Eligibility Criteria

• Age: 60 Years+
• Sex: all
• Healthy Volunteers: No
• Age Groups: Adult (18-64), Older Adult (65+)

You may qualify if:

• Diagnosis of subjective cognitive complaints (SCC) or Mild Cognitive Impairment (MCI)
• Adults at least 60 years of age (no upper age limit)
• Fluent in English
• Available informant (study partner) to complete surveys

You may not qualify if:

• Unable to consent
• Pregnant women
• Prisoners

Sponsors & Collaborators

• University of California, Davis: lead

Study Sites (1)

Alzheimer's Disease Center, University of California, Davis

Sacramento, California, 95817, United States

Location

Related Links

• Learn more or sign up for the study here!

MeSH Terms

Conditions

Cognitive Dysfunction

Interventions

desmuslin

Condition Hierarchy (Ancestors)

Cognition Disorders; Neurocognitive Disorders; Mental Disorders

Study Officials

• Sarah Farias, PhD

  University of California, Davis

  PRINCIPAL INVESTIGATOR

Study Design

• Study Type: interventional
• Phase: not applicable
• Allocation: NA
• Masking: NONE
• Purpose: SUPPORTIVE CARE
• Intervention Model: SINGLE GROUP
• Sponsor Type: OTHER
• Responsible Party: SPONSOR

Model Details: All participants will complete a curriculum involving 2-hour weekly sessions for 6-weeks.

Study Record Dates

• First Submitted: November 10, 2019
• First Posted: January 27, 2020
• Study Start: November 11, 2020
• Primary Completion: January 31, 2022
• Study Completion: December 31, 2025
• Last Updated: March 27, 2025

Record last verified: 2025-03

Data Sharing

• IPD Sharing: Will not share

Locations

US (1)