French Source-monitoring Task

NCT04237155 | Unknown DMC

• 1 other identifier: 2019-A02549-48
• Study Type: interventional
• Target: 120
• Locations: 1 country
• Sites: 1

Brief Summary

Source-monitoring is a cognitive process that refers to the ability to remember the source of an information. Source-monitoring processes are usually studied using experimental behavioral tasks. These tasks, which are very heterogeneous, are not all available in French and, for the most part, cannot be used in neuroimaging protocols. The aim of this project is to develop an experimental task which allows the measurement of source-monitoring performances, and which is adapted to neuroimaging protocols in a French-speaking population.

Conditions

Schizophrenia

Keywords

Sorce-monitoring

Outcome Measures

Primary Outcomes (1)

• Source-monitoring performances

  Performances (calculated as the number of accurate source responses and the number of errors) obtained at the new source-monitoring task and at the source-monitoring task of reference (Brunelin et al., 2006).

  one day

Study Arms (4)

Healthy controls involved in step 1

OTHER

30 healthy individuals will complete a verbal material scoring questionnaire

Other: Questionnaire

Patients with schizophrenia involved in step 1

OTHER

30 patients with schizophrenia will complete a verbal material scoring questionnaire

Other: Questionnaire

Healthy controls involved in step 2

OTHER

30 healthy individuals will complete the source-monitoring task which will be created from step 1 as well as the task of reference

Other: Cognitive tests

Patients with schizophrenia involved in step 2

OTHER

30 patients with schizophrenia will complete the source-monitoring task which will be created from step 1 as well as the task of reference

Other: Cognitive tests

Interventions

Questionnaire OTHER

Subjects will complete a verbal material scoring questionnaire

Healthy controls involved in step 1; Patients with schizophrenia involved in step 1

Cognitive tests OTHER

Subjects will complete two source-monitoring tasks: the source-monitoring task which will be created from step 1 as well as the task of reference

Healthy controls involved in step 2; Patients with schizophrenia involved in step 2

Eligibility Criteria

• Age: 18 Years - 45 Years
• Sex: all
• Healthy Volunteers: Yes
• Age Groups: Adult (18-64)

You may qualify if:

• Men and Women aged between 18 and 45
• Having given their written informed consent
• Native French speakers
• Normal or corrected-to-normal vision
• Education level greater than or equal to 8 (in years)
• For the healthy control group, no history of previous diagnosed psychiatric disorders (according to the criteria of the Diagnostic and Statistical Manual of Mental Disorders - DSM5), absence of first-degree relatives diagnosed with spectrum disorder schizophrenia and bipolar disorder (DSM).
• For the schizophrenia patients group, meeting the DSM5 criteria for schizophrenia.

You may not qualify if:

• Do not consent to be included in the study
• History of hearing impairments
• People who cannot read
• Presence of neurological or somatic diseases
• Being under tutorship or curatorship

Sponsors & Collaborators

• Hôpital le Vinatier: lead

Study Sites (1)

Centre Hospitalier le Vinatier

Bron, 69678, France

RECRUITING

MeSH Terms

Conditions

Schizophrenia

Interventions

Surveys and Questionnaires; Neuropsychological Tests

Condition Hierarchy (Ancestors)

Schizophrenia Spectrum and Other Psychotic Disorders; Mental Disorders

Intervention Hierarchy (Ancestors)

Data Collection; Epidemiologic Methods; Investigative Techniques; Health Care Evaluation Mechanisms; Quality of Health Care; Health Care Quality, Access, and Evaluation; Public Health; Environment and Public Health; Psychological Tests; Behavioral Disciplines and Activities

Central Study Contacts

Lydie Sartelet

CONTACT

0437915531; lydie.sartelet@ch-le-vinatier.fr

Study Design

• Study Type: interventional
• Phase: not applicable
• Allocation: NON RANDOMIZED
• Masking: NONE
• Purpose: OTHER
• Intervention Model: PARALLEL
• Sponsor Type: OTHER
• Responsible Party: SPONSOR

Model Details: For step 1, two populations of participants: 30 healthy volunteers and 30 patients with schizophrenia will have to complete a verbal material scoring questionnaire. For step 2, two populations of participants: 30 healthy volunteers and 30 patients with schizophrenia will have to complete the source-monitoring task which will be created from step 1 as well as the task of reference (Brunelin et al., 2008).

Study Record Dates

• First Submitted: January 17, 2020
• First Posted: January 23, 2020
• Study Start: February 7, 2020
• Primary Completion: February 1, 2023
• Study Completion: February 1, 2024
• Last Updated: March 24, 2022

Record last verified: 2022-03

Locations

FR (1)