NCT04236466

Brief Summary

Aim of the study: to compare the effect of Hyrax appliance and the Haas appliance improving the transverse skeletal and dental dimensions in cleft lip and palate patients during mixed dentition.

Trial Health

35
At Risk

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Trial has exceeded expected completion date
Enrollment
20

participants targeted

Target at below P25 for not_applicable

Timeline
Completed

Started Mar 2020

Status
unknown

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

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Study Timeline

Key milestones and dates

First Submitted

Initial submission to the registry

January 15, 2020

Completed
7 days until next milestone

First Posted

Study publicly available on registry

January 22, 2020

Completed
1 month until next milestone

Study Start

First participant enrolled

March 1, 2020

Completed
1 year until next milestone

Primary Completion

Last participant's last visit for primary outcome

March 1, 2021

Completed
Same day until next milestone

Study Completion

Last participant's last visit for all outcomes

March 1, 2021

Completed
Last Updated

January 22, 2020

Status Verified

January 1, 2020

Enrollment Period

1 year

First QC Date

January 15, 2020

Last Update Submit

January 17, 2020

Conditions

Keywords

maxillary expansion

Outcome Measures

Primary Outcomes (3)

  • Tranverse dental changes

    assessed on digital models by linear measurements (mm)

    3 months

  • Tranverse dental changes

    assessed on digital models by linear measurements(mm)

    6 months

  • Tranverse skeletal changes

    assessed on CBCT by linear and angular measurements(mm and angles)

    6 months

Secondary Outcomes (4)

  • Maxillary and mandibular anteroposterior measurements

    3 months

  • Maxillary and mandibular anteroposterior measurements

    6 months

  • Maxillary and mandibular anteroposterior measurements

    6 months

  • Vertical skeletal measurents

    6 months

Study Arms (2)

hyrax group

EXPERIMENTAL

cleft lip and palate patients with hyrax appliance

Device: hyrax appliance

haas group

EXPERIMENTAL

cleft lip and palate patients with haas appliance

Device: haas appliance

Interventions

Hyrax will be constructed with bands on maxillary first molars and wire extending on palatal surfaces of teeth till the upper canines.

hyrax group

Haas will be constructed with bands on maxillary first molars and wire extending on palatal surfaces of teeth till the upper canines. Acrylic part will be added on palate

haas group

Eligibility Criteria

Age7 Years - 11 Years
Sexall
Healthy VolunteersYes
Age GroupsChild (0-17)

You may qualify if:

  • (1) Mixed dentition; (2) Both males and females; (3) Lip repair performed between 3 and 6 months of age and palate repair performed between 12 and 24 months of age; (4) Presence of maxillary constriction and posterior crossbite and need for maxillary expansion previous to the secondary bone graft; (5) Permanent first maxillary molars present; (6) Good periodontal health; (7) No previous orthodontic treatment;

You may not qualify if:

  • (1) Presence of a syndrome in companion with the present cleft defect (2) Previous secondary alveolar bone grafting (3)Taking medications affecting growth

Contact the study team to confirm eligibility.

Sponsors & Collaborators

MeSH Terms

Conditions

Cleft Lip

Condition Hierarchy (Ancestors)

Lip DiseasesMouth DiseasesStomatognathic DiseasesMouth AbnormalitiesStomatognathic System AbnormalitiesCongenital AbnormalitiesCongenital, Hereditary, and Neonatal Diseases and Abnormalities

Central Study Contacts

Study Design

Study Type
interventional
Phase
not applicable
Allocation
RANDOMIZED
Masking
SINGLE
Who Masked
OUTCOMES ASSESSOR
Purpose
TREATMENT
Intervention Model
PARALLEL
Sponsor Type
OTHER
Responsible Party
PRINCIPAL INVESTIGATOR
PI Title
teaching assistant

Study Record Dates

First Submitted

January 15, 2020

First Posted

January 22, 2020

Study Start

March 1, 2020

Primary Completion

March 1, 2021

Study Completion

March 1, 2021

Last Updated

January 22, 2020

Record last verified: 2020-01