Evaluating Radiomorphometric Indices and Fractal Dimension of the Pediatric Oncology Patients on Panoramic Images

NCT04213482 | Completed

• 1 other identifier: 2018/209
• Study Type: observational
• Target: 100
• Locations: 1 country
• Sites: 1

Brief Summary

This study evaluated pediatric oncology patients in terms of quality of bone and determine any relation between bone quality and radiotherapy/chemotherapy. The alternative hypothesis is that the bone quality of the oncology patients who received radiotherapy/chemotherapy is lower than the control group.

Conditions

Oncology; Bone Loss

Keywords

pediatric oncology; fractal analysis; panoramic mandibular indices; radiotherapy; chemotherapy

Outcome Measures

Primary Outcomes (1)

• Bone Mineral Density (BMD)

  Fractal Dimension of the mandibular bone in patients with pediatric oncologic diseases will be measured on dental panoramic images to asses bone mineral density of mandibula. Image J software will be used to Fractal Analysis measurements.

  Participants to undergo a single assessment; to be measured at least 1 year after completion of oncologic therapy

Study Arms (2)

oncology patients

For this study, panoramic images were taken from pediatric patients who received radiotherapy and/or chemotherapy because of any oncologic disease.

Radiation: Panoramic Radiography

healthy

panoramic images of patients(pediatric) who have no systemic disease were collected from the archive of dental radiology clinic of the university hospital.

Radiation: Panoramic Radiography

Interventions

Panoramic Radiography RADIATION

Diagnostic Panoramic Dental Radiographs were taken.

healthy; oncology patients

Eligibility Criteria

• Age: 6 Years - 23 Years
• Sex: all
• Healthy Volunteers: Yes
• Age Groups: Child (0-17), Adult (18-64)
• Sampling Method: Non-Probability Sample

Study Population

Patients received chemotherapy and radiotherapy for a Pediatric oncologic disease

You may qualify if:

• to have been treated for any oncological diseases in childhood
• oncological treatment completed at least one year ago

You may not qualify if:

• ongoing oncological treatment
• patients who unwilling to participate to study

Sponsors & Collaborators

• Nuh Naci Yazgan University: lead

Study Sites (1)

Nuh Naci Yazgan University

Kayseri, Kocasinan, 38170, Turkey (Türkiye)

Location

MeSH Terms

Conditions

Neoplasms; Bone Diseases, Metabolic

Interventions

Radiography, Panoramic

Condition Hierarchy (Ancestors)

Bone Diseases; Musculoskeletal Diseases; Metabolic Diseases; Nutritional and Metabolic Diseases

Intervention Hierarchy (Ancestors)

Radiography, Dental; Radiography; Diagnostic Imaging; Diagnostic Techniques and Procedures; Diagnosis; Diagnosis, Oral; Dentistry

Study Design

• Study Type: observational
• Observational Model: CASE CONTROL
• Time Perspective: RETROSPECTIVE
• Sponsor Type: OTHER
• Responsible Party: PRINCIPAL INVESTIGATOR
• PI Title: Assistant Professor

Study Record Dates

• First Submitted: December 23, 2019
• First Posted: December 30, 2019
• Study Start: May 15, 2018
• Primary Completion: August 20, 2018
• Study Completion: December 20, 2019
• Last Updated: December 30, 2019

Record last verified: 2019-12

Locations

TU (1)