Evaluation, the Histomorphometric Study of Nanocrystalline Hydroxyapatite (Nano Bone) Wif Lovastatin in the Preservation of the Tooth Socket
the Histomorphometric Study of Nanocrystalline Hydroxyapatite (Nano Bone) With Lovastatin in the Preservation of the Tooth Socket
1 other identifier
interventional
20
1 country
1
Brief Summary
Twenty patients referring to periodontics department of Boroujerd Azad university of dentistry after obtaining consent to participate in the research project, which have more than 20 teeth, are over 18 years old and require socket preservation surgery to tooth extraction for the periodontal problem, caries or Fractures were selected.
Trial Health
Trial Health Score
Automated assessment based on enrollment pace, timeline, and geographic reach
participants targeted
Target at below P25 for phase_2
Started Feb 2018
Shorter than P25 for phase_2
1 active site
Health score is calculated from publicly available data and should be used for screening purposes only.
Trial Relationships
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Study Timeline
Key milestones and dates
Study Start
First participant enrolled
February 22, 2018
CompletedFirst Submitted
Initial submission to the registry
February 9, 2019
CompletedPrimary Completion
Last participant's last visit for primary outcome
March 30, 2019
CompletedFirst Posted
Study publicly available on registry
June 11, 2019
CompletedStudy Completion
Last participant's last visit for all outcomes
July 30, 2019
CompletedJune 11, 2019
June 1, 2019
1.1 years
February 9, 2019
June 10, 2019
Conditions
Outcome Measures
Primary Outcomes (1)
Socket preservation with Lovastatin as evaluated by the amount of bone formation volume
3 month
Study Arms (2)
lovastatin 40 mg with bone graft
ACTIVE COMPARATORafter tooth extraction, put teh lovastatin40 mg wif bone graft wifin tooth socket
without drug with bone graft
ACTIVE COMPARATORafter tooth extraction, put the bone graft wifin tooth socket
Interventions
after tooth extraction, put teh lovastatin40 mg wif bone graft wifin tooth socket
after tooth extraction, put teh bone graft wifin tooth socket
Eligibility Criteria
You may qualify if:
- at least 18 years old
- tooth fracture, root caries
- Patients are volunteered for placement of the implant
You may not qualify if:
- systemic diseases
- Pregnancy and breastfeeding
- malignancy, radiation therapy,
- history of periodontal surgery during the six months ago.
- medicine(phosphonates, antibiotic,...)
Contact the study team to confirm eligibility.
Sponsors & Collaborators
Study Sites (1)
Amirhossein Farahmand
Tehran, 19, Iran
MeSH Terms
Conditions
Interventions
Condition Hierarchy (Ancestors)
Intervention Hierarchy (Ancestors)
Central Study Contacts
Study Design
- Study Type
- interventional
- Phase
- phase 2
- Allocation
- RANDOMIZED
- Masking
- QUADRUPLE
- Who Masked
- PARTICIPANT, CARE PROVIDER, INVESTIGATOR, OUTCOMES ASSESSOR
- Purpose
- TREATMENT
- Intervention Model
- PARALLEL
- Sponsor Type
- OTHER
- Responsible Party
- PRINCIPAL INVESTIGATOR
- PI Title
- assistant prof
Study Record Dates
First Submitted
February 9, 2019
First Posted
June 11, 2019
Study Start
February 22, 2018
Primary Completion
March 30, 2019
Study Completion
July 30, 2019
Last Updated
June 11, 2019
Record last verified: 2019-06
Data Sharing
- IPD Sharing
- Will not share