Dietary Practices and Metabolic Syndrome in the Young Adult Population of Rwanda

NCT04204538 | Completed

• 1 other identifier: EC/2019/1577
• Study Type: observational
• Target: 1,247
• Locations: 1 country
• Sites: 1

Brief Summary

Policy makers in Rwanda have recently highlighted the importance of promoting healthy diets and lifestyle in response to rapidly increasing rates of obesity. This project will provide evidence on shifts in diet and nutritional status in urban dwellers as compared to the traditional diet and lifestyle in rural areas as a basis for a targeted public health policy for Rwanda.

Conditions

Metabolic Syndrome; Nutritional Status; Diet Habit

Keywords

Food Frequency Questionnaire; Dietary patterns; Risk factors; metabolic syndrome; Nutritional transition

Outcome Measures

Primary Outcomes (7)

• Prevalence of the different dietary patterns

  Dietary patterns will be identified using exploratory factor analysis on the food groups collected using the semi-quantitative Food Frequency Questionnaire. The dietary pattern identified will differ from plant\_based diet and legume\_based diet to western diet.

  Through study completion (an average of 6 months)

• Prevalence of large waist circumference

  Large waist circumference \[\> 89 centimeters for women and \>102 centimeters for men\]

  Through study completion (an average of 6 months)

• Prevalence of high triglyceride concentrations

  High triglyceride level \[\>150 milligrams per deciliter (mg/dL)\]

  Through study completion (an average of 6 months)

• Prevalence of high-density lipoprotein (HDL) cholesterol

  Reduced high-density lipoprotein (HDL) cholesterol \[\< 40 mg/dL in men or \< 50 mg/dL in women\]

  Through study completion (an average of 6 months)

• Prevalence of high blood pressure

  Increased blood pressure \[\> 130/85 mm Hg\]

  Through study completion (an average of 6 months)

• Prevalence of high levels of fasting blood sugar

  Elevated fasting blood sugar \[\>100 mg/dL\]

  Through study completion (an average of 6 months)

• Prevalence of participants with nutrition knowledge

  Nutritional knowledge of macronutrients, micronutrients, water intake, diet and disease will be collected using a multiple choice answers. Each question had one mark for every correct response chosen. Using a marking scheme for nutritional knowledge test the scores were rated on score percentages using eight cut off points, with scores less than 20% indicating a bad nutritional knowledge, 50-59% satisfactory and Excellent for those scoring 80% and more.

  Through study completion (an average of 6 months)

Secondary Outcomes (1)

• Prevalence of Food Insecure Households

  Through study completion (an average of 6 months)

Study Arms (2)

Urban

Young adults living in urban communities of Rwanda

Other: Dietary habits; Other: Risk factors associated with metabolic syndrome

Rural

Young adults living in rural communities of Rwanda

Other: Dietary habits; Other: Risk factors associated with metabolic syndrome

Interventions

Dietary habits OTHER

Data collected using food frequency questionnaire

Rural; Urban

Risk factors associated with metabolic syndrome OTHER

Data collected on nutritional status, biochemical indicators and other risk factors associated with metabolic syndrome

Rural; Urban

Eligibility Criteria

• Age: 18 Years - 35 Years
• Sex: all
• Healthy Volunteers: Yes
• Age Groups: Adult (18-64)
• Sampling Method: Non-Probability Sample

Study Population

Participants will be selected randomly from the general population. Eligible subjects who agree to participate (informed consent) will be enrolled in the study.

You may qualify if:

• Permanent residence of the selected urban or rural villages
• Holding a valid health insurance card
• Aged between 18 and 35 years
• Signing informed consent form
• Registration in city demographic system, since study participants will be selected from population registration cards at village level,
• Accept enumerators for home visit and data collection
• Accept to visit the laboratory for blood sample collection,
• Not suffering from any chronic disease such as VIH/ AIDS, diabetes, asthma, etc.

You may not qualify if:

• Lactating, pregnant, and recently delivering (less than six month-postpartum) women
• Physical disabilities that can prevent participants from working
• Mental disability such as clinically diagnosed depression, anxiety disorders, eating disorders and addictive behaviors.

Sponsors & Collaborators

• University Ghent: lead
• University of Rwanda: collaborator
• Institut de Recherche en Sciences de la Sante, Burkina Faso: collaborator

Study Sites (1)

University of Rwanda

Kigali, Rwanda

Location

Related Publications (4)

• Bowen L, Ebrahim S, De Stavola B, Ness A, Kinra S, Bharathi AV, Prabhakaran D, Reddy KS. Dietary intake and rural-urban migration in India: a cross-sectional study. PLoS One. 2011;6(6):e14822. doi: 10.1371/journal.pone.0014822. Epub 2011 Jun 22.

  PMID: 21731604 BACKGROUND

• Boutayeb A. The double burden of communicable and non-communicable diseases in developing countries. Trans R Soc Trop Med Hyg. 2006 Mar;100(3):191-9. doi: 10.1016/j.trstmh.2005.07.021. Epub 2005 Nov 4.

  PMID: 16274715 BACKGROUND

• Swinburn BA, Kraak VI, Allender S, Atkins VJ, Baker PI, Bogard JR, Brinsden H, Calvillo A, De Schutter O, Devarajan R, Ezzati M, Friel S, Goenka S, Hammond RA, Hastings G, Hawkes C, Herrero M, Hovmand PS, Howden M, Jaacks LM, Kapetanaki AB, Kasman M, Kuhnlein HV, Kumanyika SK, Larijani B, Lobstein T, Long MW, Matsudo VKR, Mills SDH, Morgan G, Morshed A, Nece PM, Pan A, Patterson DW, Sacks G, Shekar M, Simmons GL, Smit W, Tootee A, Vandevijvere S, Waterlander WE, Wolfenden L, Dietz WH. The Global Syndemic of Obesity, Undernutrition, and Climate Change: The Lancet Commission report. Lancet. 2019 Feb 23;393(10173):791-846. doi: 10.1016/S0140-6736(18)32822-8. Epub 2019 Jan 27. No abstract available.

  PMID: 30700377 BACKGROUND

• Janjua NZ, Mahmood B, Bhatti JA, Khan MI. Association of household and community socioeconomic position and urbanicity with underweight and overweight among women in Pakistan. PLoS One. 2015 Apr 2;10(4):e0122314. doi: 10.1371/journal.pone.0122314. eCollection 2015.

  PMID: 25835540 BACKGROUND

Biospecimen

Retention: SAMPLES WITHOUT DNA

Serum samples

MeSH Terms

Conditions

Metabolic Syndrome; Feeding Behavior

Condition Hierarchy (Ancestors)

Insulin Resistance; Hyperinsulinism; Glucose Metabolism Disorders; Metabolic Diseases; Nutritional and Metabolic Diseases; Behavior, Animal; Behavior

Study Officials

• Stefaan De Henauw, Md. PhD

  University Ghent

  PRINCIPAL INVESTIGATOR

• Souheila Abbeddou, MSc. PhD

  University Ghent

  PRINCIPAL INVESTIGATOR

• Hilda Vasanthakaalam, PhD

  University of Rwanda

  PRINCIPAL INVESTIGATOR

• Jerome Some, Md. PhD

  Institut de Recherche en Sciences de la Sante, Ouagadougou, Burkina Faso

  PRINCIPAL INVESTIGATOR

Study Design

• Study Type: observational
• Observational Model: OTHER
• Time Perspective: CROSS SECTIONAL
• Sponsor Type: OTHER
• Responsible Party: SPONSOR

Study Record Dates

• First Submitted: November 27, 2019
• First Posted: December 19, 2019
• Study Start: November 1, 2021
• Primary Completion: December 31, 2023
• Study Completion: December 31, 2023
• Last Updated: February 7, 2024

Record last verified: 2024-02

Data Sharing

• IPD Sharing: Will not share

Locations

RW (1)