NCT05120778

Brief Summary

The purpose of this study is to determine if an exercise training intervention together with conventional medical treatment can decrease the annual healthcare cost in patients with metabolic syndrome.

Trial Health

35
At Risk

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Trial has exceeded expected completion date
Enrollment
207

participants targeted

Target at P75+ for not_applicable

Timeline
Completed

Started Dec 2021

Longer than P75 for not_applicable

Status
unknown

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

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Study Timeline

Key milestones and dates

First Submitted

Initial submission to the registry

September 27, 2021

Completed
2 months until next milestone

First Posted

Study publicly available on registry

November 15, 2021

Completed
16 days until next milestone

Study Start

First participant enrolled

December 1, 2021

Completed
2.1 years until next milestone

Primary Completion

Last participant's last visit for primary outcome

December 31, 2023

Completed
2 years until next milestone

Study Completion

Last participant's last visit for all outcomes

December 31, 2025

Completed
Last Updated

November 15, 2021

Status Verified

November 1, 2021

Enrollment Period

2.1 years

First QC Date

September 27, 2021

Last Update Submit

November 3, 2021

Conditions

Keywords

metabolic syndromeexercise traininghealthcare costhigh-intensity interval trainingstrength training

Outcome Measures

Primary Outcomes (1)

  • Change of Annual healthcare cost

    From unified medical records, all clinical and paraclinical interventions including pharmacological treatment, diagnostic or therapeutic procedures and primary care and specialized medical consultations will be included

    Baseline, month 12 and 24

Secondary Outcomes (6)

  • Cardiorespiratory fitness

    Baseline, month 4,12, and 24.

  • Body composition

    Baseline, month 4,12, and 24.

  • Blood lipids profile

    Baseline, month 4,12, and 24.

  • Glycemia

    Baseline, month 4,12, and 24.

  • Blood pressure

    Baseline, month 4,12, and 24.

  • +1 more secondary outcomes

Other Outcomes (3)

  • Compliance to Exercise volume prescription .

    Month 4

  • compliance to Exercise intensity prescription.

    Month 4

  • Daily physical activity

    Month 4,12, and 24.

Study Arms (2)

conventional medical treatment

EXPERIMENTAL

Volunteers will maintain habitual medical treatment.

Other: conventional medical treatment

exercise training + conventional medical treatment

EXPERIMENTAL

Volunteers will maintain habitual medical treatment and will participate in a 16-week exercise training based on high-intensity interval training (stationary bikes), and strength training (weight-bearing exercises).

Behavioral: exercise trainingOther: conventional medical treatment

Interventions

as appear in arm description.

exercise training + conventional medical treatment

participants will maintain habitual medical treatment prescribed by primary care and specialized physicians from the public health service.

conventional medical treatmentexercise training + conventional medical treatment

Eligibility Criteria

Age30 Years - 70 Years
Sexall
Healthy VolunteersNo
Age GroupsAdult (18-64), Older Adult (65+)

You may qualify if:

  • Fulfilling criteria for metabolic syndrome diagnosis.

You may not qualify if:

  • At baseline, engagement to an exercise training program for the last 6 months.

Contact the study team to confirm eligibility.

Sponsors & Collaborators

MeSH Terms

Conditions

Metabolic Syndrome

Interventions

Exercise

Condition Hierarchy (Ancestors)

Insulin ResistanceHyperinsulinismGlucose Metabolism DisordersMetabolic DiseasesNutritional and Metabolic Diseases

Intervention Hierarchy (Ancestors)

Motor ActivityMovementMusculoskeletal Physiological PhenomenaMusculoskeletal and Neural Physiological Phenomena

Study Officials

  • Ricardo Mora-Rodriguez, PhD

    University of Castilla-La Mancha

    PRINCIPAL INVESTIGATOR

Central Study Contacts

Ricardo Mora-Rodriguez, PhD

CONTACT

Study Design

Study Type
interventional
Phase
not applicable
Allocation
RANDOMIZED
Masking
NONE
Purpose
HEALTH SERVICES RESEARCH
Intervention Model
PARALLEL
Model Details: Cluster randomized clinical trial
Sponsor Type
OTHER
Responsible Party
SPONSOR

Study Record Dates

First Submitted

September 27, 2021

First Posted

November 15, 2021

Study Start

December 1, 2021

Primary Completion

December 31, 2023

Study Completion

December 31, 2025

Last Updated

November 15, 2021

Record last verified: 2021-11

Data Sharing

IPD Sharing
Will not share