NCT04198311

Brief Summary

Project STAR aims to examine the feasibility, acceptability, and initial efficacy of a CBT-I supplement to outpatient alcohol and substance use treatment.

Trial Health

43
At Risk

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Trial has exceeded expected completion date
Enrollment
40

participants targeted

Target at P25-P50 for not_applicable

Timeline
Completed

Started Aug 2020

Typical duration for not_applicable

Geographic Reach
1 country

1 active site

Status
unknown

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

First Submitted

Initial submission to the registry

December 9, 2019

Completed
4 days until next milestone

First Posted

Study publicly available on registry

December 13, 2019

Completed
9 months until next milestone

Study Start

First participant enrolled

August 26, 2020

Completed
2.3 years until next milestone

Primary Completion

Last participant's last visit for primary outcome

December 31, 2022

Completed
Same day until next milestone

Study Completion

Last participant's last visit for all outcomes

December 31, 2022

Completed
Last Updated

October 10, 2022

Status Verified

March 1, 2022

Enrollment Period

2.3 years

First QC Date

December 9, 2019

Last Update Submit

October 6, 2022

Conditions

Keywords

sleepalcoholdrinkinginsomniaoutpatientinpatientdrug use

Outcome Measures

Primary Outcomes (3)

  • Recruitment

    The number of participants who complete baseline.

    Assessed at Post-Treatment (week 6)

  • Retention

    The number of participants who complete all treatment sessions

    Assessed at Post-Treatment (week 6)

  • Treatment Satisfaction

    The satisfaction rating participants give the treatment.Assessed using the Client Satisfaction Questionnaire; The Client Satisfaction Questionnaire is an 8-item measure of satisfaction with treatment that has been validated in substance use treatment settings. Items are scores from 1 to 4, with higher scores indicating greater satisfaction with treatment.

    Assessed at Post-Treatment (week 6)

Secondary Outcomes (9)

  • Abstinence

    Change from baseline to post-treatment (week 6) to follow-up (week 12)

  • Heavy-Drinking Days

    Change from baseline to post-treatment (week 6) to follow-up (week 12)

  • Substance Use Days

    Change from baseline to post-treatment (week 6) to follow-up (week 12)

  • Alcohol Problems

    Change from baseline to post-treatment (week 6) to follow-up (week 12)

  • Alcohol or Other Drugs as Sleep Aids

    Change from baseline to post-treatment (week 6) to follow-up (week 12)

  • +4 more secondary outcomes

Other Outcomes (4)

  • Treatment-related Learning

    Change from baseline to post-treatment (week 6)

  • Executive Functioning - Delayed Discounting

    Change from baseline to post-treatment (week 6) to follow-up (week 12)

  • Executive Functioning - Working Memory

    Change from baseline to post-treatment (week 6) to follow-up (week 12)

  • +1 more other outcomes

Study Arms (1)

Cognitive-Behavioral Therapy for Insomnia (CBT-I)

EXPERIMENTAL

Individual Cognitive Behavioral Therapy for Insomnia (CBT-I) delivered once a week for five (5) weeks

Behavioral: CBT-I

Interventions

CBT-IBEHAVIORAL

CBT-I will be delivered individually, in five weekly sessions. Intervention components include sleep hygiene, sleep restriction, stimulus control, relaxation, cognitive therapy.

Also known as: Cognitive-Behavioral Therapy for Insomnia
Cognitive-Behavioral Therapy for Insomnia (CBT-I)

Eligibility Criteria

Age18 Years+
Sexall
Healthy VolunteersNo
Age GroupsAdult (18-64), Older Adult (65+)

You may qualify if:

  • Participation in alcohol or substance use treatment in the Columbia, MO area
  • DSM-5 criteria for moderate to severe Alcohol Use Disorder of Substance Use Disorder
  • DSM-5 episodic criterion (duration at least 1 month) for Insomnia Disorder

You may not qualify if:

  • unable to provide informed consent
  • cognitive impairment
  • continuous sobriety for 2+ months at baseline
  • untreated sleep disorder requiring more than behavioral treatment for insomnia
  • severe psychiatric disorder that requires immediate clinical attention
  • initiation of a sleep medication in the past six (6) weeks

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

University of Missouri-Columbia

Columbia, Missouri, 65212, United States

RECRUITING

Related Publications (1)

  • Miller MB, Freeman LK, Helle AC, Hall NA, DiBello AM, McCrae CS. Comparative feasibility and preliminary efficacy of CBT for insomnia among adults seeking and not seeking addiction treatment. J Sleep Res. 2024 Apr;33(2):e13969. doi: 10.1111/jsr.13969. Epub 2023 Jul 9.

MeSH Terms

Conditions

Sleep Initiation and Maintenance DisordersAlcoholismSubstance-Related Disorders

Interventions

Cognitive Behavioral Therapy

Condition Hierarchy (Ancestors)

Sleep Disorders, IntrinsicDyssomniasSleep Wake DisordersNervous System DiseasesMental DisordersAlcohol-Related DisordersChemically-Induced Disorders

Intervention Hierarchy (Ancestors)

Behavior TherapyPsychotherapyBehavioral Disciplines and Activities

Central Study Contacts

Study Design

Study Type
interventional
Phase
not applicable
Allocation
NA
Masking
NONE
Purpose
TREATMENT
Intervention Model
SINGLE GROUP
Model Details: Subjects will participate in sessions individual Cognitive Behavioral Therapy for Insomnia (CBT-I).
Sponsor Type
OTHER
Responsible Party
PRINCIPAL INVESTIGATOR
PI Title
Professor, Psychiatry

Study Record Dates

First Submitted

December 9, 2019

First Posted

December 13, 2019

Study Start

August 26, 2020

Primary Completion

December 31, 2022

Study Completion

December 31, 2022

Last Updated

October 10, 2022

Record last verified: 2022-03

Locations