NCT04181151

Brief Summary

Latissimus Dorsi (LD); Medial sacrum, lumbar vertebrae and lower thoracic vertebrae 10-12 lateral to the spinous processus. It is a fan-like wide muscle that connects to the inferior angle of the scapula and ribs, adheres to the anterior surface of the proximal humerus and continues with aponeurosis of the contralateral Gluteus Maximus below. The activation of the LD muscle during the functional reach activity, which we use most frequently in daily living activities, affects the upper extremity and trunk movements. Therefore it is important muscle that affects the quality of movement. The study include individuals with stroke that diagnosed by the neurologist and include healthy subjects. During sitting activity, they will be required to reach three different distances in the sagittal and scapular plane: arm length, 125% of the arm length and end point where it can reach the modified functional reach test. During the activity, electromyography (EMG) activation of latissimus dorsi, anterior deltoid and erector spina muscles will be examined with electromyographic device. Hypothesis originating from the investigation: H1: Latissimus dorsi muscle segments show different activation during functional reach activity. H2: Activation of latissimus dorsi muscle segments is affected by reaching direction during functional reach activity. H3: Activation of latissimus dorsi muscle segments is affected by reaching distance during functional reach activity.

Trial Health

87
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
12

participants targeted

Target at below P25 for all trials

Timeline
Completed

Started Jan 2019

Geographic Reach
1 country

1 active site

Status
completed

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

Study Start

First participant enrolled

January 1, 2019

Completed
7 months until next milestone

Primary Completion

Last participant's last visit for primary outcome

August 7, 2019

Completed
4 months until next milestone

First Submitted

Initial submission to the registry

November 25, 2019

Completed
4 days until next milestone

First Posted

Study publicly available on registry

November 29, 2019

Completed
1.1 years until next milestone

Study Completion

Last participant's last visit for all outcomes

December 29, 2020

Completed
Last Updated

April 20, 2022

Status Verified

April 1, 2022

Enrollment Period

7 months

First QC Date

November 25, 2019

Last Update Submit

April 13, 2022

Conditions

Keywords

latissimus dorsistrokeelectromyographyreaching activitymuscle activation

Outcome Measures

Primary Outcomes (1)

  • Surface electromyographic measurement

    Muscle activation measurement It is an 8-channel system for measuring signals come from muscles (Noraxon Telemyo DTS system, Scottsdale, USA).

    90 minutes

Study Arms (2)

Stroke patients

Other: Electromyographic device

Healthy Subjects

Other: Electromyographic device

Interventions

An 8-channel surface EMG system (Noraxon Telemyo DTS system, Scottsdale, USA) will be used to measure signals from muscles during surface electromyography measurements.

Healthy SubjectsStroke patients

Eligibility Criteria

Age30 Years - 60 Years
Sexall
Healthy VolunteersYes
Age GroupsAdult (18-64)
Sampling MethodNon-Probability Sample
Study Population

Hacettepe University Neurological Rehabilitation Unit

You may qualify if:

  • diagnosed with stroke by a neurologist
  • least 6 mounts after stroke
  • Fugl Meyer Upper Extremity Motor Rating Scale with a value of 40 and above,
  • independent sitting,
  • Mini Mental Status Scale (MMSE)\> 24,
  • age.

You may not qualify if:

  • neurodegenerative disease other than stroke
  • presence of neglect
  • presence of apraxia
  • uncorrected visual impairment
  • neuromusculoskeletal pathologies
  • neck and shoulder pain lasting more than 3 months

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

Hacettepe University

Ankara, Sıhhiye/ANKARA, Turkey (Türkiye)

Location

Related Publications (6)

  • Bogduk N, Johnson G, Spalding D. The morphology and biomechanics of latissimus dorsi. Clin Biomech (Bristol). 1998 Sep;13(6):377-385. doi: 10.1016/s0268-0033(98)00102-8.

    PMID: 11415812BACKGROUND
  • Dickstein R, Shefi S, Marcovitz E, Villa Y. Anticipatory postural adjustment in selected trunk muscles in post stroke hemiparetic patients. Arch Phys Med Rehabil. 2004 Feb;85(2):261-7. doi: 10.1016/j.apmr.2003.05.011.

    PMID: 14966711BACKGROUND
  • Wickham JB, Brown JM. Muscles within muscles: the neuromotor control of intra-muscular segments. Eur J Appl Physiol Occup Physiol. 1998 Aug;78(3):219-25. doi: 10.1007/s004210050410.

    PMID: 9720999BACKGROUND
  • Brown JM, Wickham JB, McAndrew DJ, Huang XF. Muscles within muscles: Coordination of 19 muscle segments within three shoulder muscles during isometric motor tasks. J Electromyogr Kinesiol. 2007 Feb;17(1):57-73. doi: 10.1016/j.jelekin.2005.10.007. Epub 2006 Feb 2.

    PMID: 16458022BACKGROUND
  • Hermens HJ, Freriks B, Disselhorst-Klug C, Rau G. Development of recommendations for SEMG sensors and sensor placement procedures. J Electromyogr Kinesiol. 2000 Oct;10(5):361-74. doi: 10.1016/s1050-6411(00)00027-4.

    PMID: 11018445BACKGROUND
  • Kaya Benli T, Kara D, Dulger E, Bilgin S. Electromyography study of six parts of the latissimus dorsi during reaching tasks while seated: A comparison between healthy subjects and stroke patients. J Electromyogr Kinesiol. 2023 Jun;70:102770. doi: 10.1016/j.jelekin.2023.102770. Epub 2023 Mar 25.

Related Links

MeSH Terms

Conditions

Stroke

Condition Hierarchy (Ancestors)

Cerebrovascular DisordersBrain DiseasesCentral Nervous System DiseasesNervous System DiseasesVascular DiseasesCardiovascular Diseases

Study Officials

  • Tuba KAYA, R.A.

    Hacettepe University

    PRINCIPAL INVESTIGATOR
  • Sevil BİLGİN, Assoc. Prof.

    Hacettepe University

    STUDY DIRECTOR
  • Muhammed KILINÇ, Assoc. Prof.

    Hacettepe University

    STUDY CHAIR
  • Esra DÜLGER, R.A.

    Hacettepe University

    STUDY CHAIR

Study Design

Study Type
observational
Observational Model
OTHER
Time Perspective
PROSPECTIVE
Target Duration
1 Day
Sponsor Type
OTHER
Responsible Party
PRINCIPAL INVESTIGATOR
PI Title
Research Assistant

Study Record Dates

First Submitted

November 25, 2019

First Posted

November 29, 2019

Study Start

January 1, 2019

Primary Completion

August 7, 2019

Study Completion

December 29, 2020

Last Updated

April 20, 2022

Record last verified: 2022-04

Data Sharing

IPD Sharing
Will not share

Locations