Effects of a Caffeine- and Protein-Containing Coffee Beverage on Metabolism and Muscular Performance

NCT04180787 | Completed

• 1 other identifier: 20-0130
• Study Type: interventional
• Target: 19
• Locations: 1 country
• Sites: 1

Brief Summary

The purpose of this randomized, double-blind, crossover study is to investigate the effects of Bang® Keto Coffee on resting and post-exercise metabolism and muscular performance during lower body resistance exercise.

Conditions

Exercise Performance; Metabolism

Outcome Measures

Primary Outcomes (10)

• Isometric Force Production

  Isometric force production on mechanized squat device

  Assessed approximately 45 minutes after beverage ingestion

• Isometric Force Production

  Isometric force production on mechanized squat device

  Assessed approximately 80 minutes after beverage ingestion

• Isokinetic Force Production

  Isokinetic force production on mechanized squat device

  Assessed approximately 45 minutes after beverage ingestion

• Isokinetic Force Production

  Isokinetic force production on mechanized squat device.

  Assessed approximately 80 minutes after beverage ingestion

• Maximal Lower Body Strength

  One-repetition maximum on hip sled machine

  Assessed approximately 75 minutes after beverage ingestion

• Maximal Lower Body Endurance

  Repetitions to failure on hip sled machine

  Assessed approximately 75 minutes after beverage ingestion (following maximal lower body strength testing)

• Change in Metabolic Rate

  Metabolic rate assessed via indirect calorimetry

  Change in metabolic rate between: 1) before beverage ingestion (baseline) and 2) beginning approximately 10 minutes after completion of beverage ingestion

• Change in Metabolic Rate

  Metabolic rate assessed via indirect calorimetry

  Change in metabolic rate between: 1) before beverage ingestion (baseline) and 2) beginning approximately 5 minutes after completion of all exercise testing

• Change in Respiratory Exchange Ratio

  Respiratory exchange ratio as assessed via indirect calorimetry

  Change in respiratory exchange ratio between: 1) before beverage ingestion (baseline) and 2) beginning approximately 10 minutes after completion of beverage ingestion

• Change in Respiratory Exchange Ratio

  Respiratory exchange ratio as assessed via indirect calorimetry

  Change in respiratory exchange ratio between: 1) before beverage ingestion (baseline) and 2) beginning approximately 5 minutes after completion of all exercise testing.

Study Arms (2)

Keto Coffee

EXPERIMENTAL

VPX Bang® Keto Coffee beverage

Dietary Supplement: Beverage Consumption

Placebo

PLACEBO COMPARATOR

Flavor-matched placebo beverage

Dietary Supplement: Beverage Consumption

Interventions

Beverage Consumption DIETARY_SUPPLEMENT

Participants will consume either VPX Bang® Keto Coffee beverage or flavor-matched placebo beverage in each condition.

Keto Coffee; Placebo

Eligibility Criteria

• Age: 18 Years - 40 Years
• Sex: all
• Healthy Volunteers: Yes
• Age Groups: Adult (18-64)

You may qualify if:

• Between the ages of 18 and 40
• Generally healthy (defined as an absence of any disease or medical condition which could potentially be negatively affected by consumption of the commercially available dietary supplement of performance of exercise, including but not limited to musculoskeletal or cardiovascular diseases).
• Resistance-trained, defined as completing 3+ resistance training sessions per week for at least one year and including at least weekly training of the lower body through a multi-joint exercise such as the squat or leg press.
• Regular caffeine consumption, defined as an average self-reported daily intake of 200+ mg of caffeine, which is equivalent to approximately 2 cups of coffee.

You may not qualify if:

• Pregnant or breastfeeding (for female participants)
• Taking prescription medication which could reasonably make participation unsafe for the participant or influence study outcomes
• An inability to complete lower body resistance exercise due to injury or medical condition
• Self-reported caffeine sensitivity, as indicated by unwanted side effects when caffeine is consumed.
• Allergy to any of the ingredients in the commercially available dietary supplement
• Self-reported claustrophobia (due to metabolism testing)

Sponsors & Collaborators

• Texas Tech University: lead
• Vital Pharmaceuticals, Inc.: collaborator

Study Sites (1)

Department of Kinesiology & Sport Management

Lubbock, Texas, 79409, United States

Location

Related Publications (1)

• Harty PS, Stratton MT, Escalante G, Rodriguez C, Dellinger JR, Williams AD, White SJ, Smith RW, Johnson BA, Sanders MB, Tinsley GM. Effects of Bang(R) Keto Coffee Energy Drink on Metabolism and Exercise Performance in Resistance-Trained Adults: A Randomized, Double-blind, Placebo-controlled, Crossover Study. J Int Soc Sports Nutr. 2020 Aug 24;17(1):45. doi: 10.1186/s12970-020-00374-5.

  PMID: 32831109 DERIVED

Study Officials

• Grant M Tinsley, PhD

  Texas Tech University

  PRINCIPAL INVESTIGATOR

Study Design

• Study Type: interventional
• Phase: not applicable
• Allocation: RANDOMIZED
• Masking: TRIPLE
• Who Masked: PARTICIPANT, INVESTIGATOR, OUTCOMES ASSESSOR
• Purpose: OTHER
• Intervention Model: CROSSOVER
• Sponsor Type: OTHER
• Responsible Party: SPONSOR

Study Record Dates

• First Submitted: November 20, 2019
• First Posted: November 29, 2019
• Study Start: December 5, 2019
• Primary Completion: March 9, 2020
• Study Completion: March 9, 2020
• Last Updated: May 7, 2020

Record last verified: 2020-05

Locations

US (1)