Effects of Herbal Supplements on Endurance Exercise Performance
1 other identifier
interventional
13
1 country
1
Brief Summary
Cordyceps and Rhodiola are two common herbal supplements marketed and consumed as adaptogens to athletes with regard to enhanced performance. The effects of these supplements has been well studied in animals but whether or not the same effects translate to humans is still unclear. Thus, the primary purpose of this study is to determine whether combined supplementation of Rhodiola and Cordyceps, compared to Rhodiola alone and placebo, will demonstrate a greater improvement in oxygen consumption (ie. VO2 max).
Trial Health
Trial Health Score
Automated assessment based on enrollment pace, timeline, and geographic reach
participants targeted
Target at below P25 for not_applicable
Started May 2019
Shorter than P25 for not_applicable
1 active site
Health score is calculated from publicly available data and should be used for screening purposes only.
Trial Relationships
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Study Timeline
Key milestones and dates
First Submitted
Initial submission to the registry
April 24, 2019
CompletedFirst Posted
Study publicly available on registry
April 29, 2019
CompletedStudy Start
First participant enrolled
May 1, 2019
CompletedPrimary Completion
Last participant's last visit for primary outcome
December 1, 2019
CompletedStudy Completion
Last participant's last visit for all outcomes
December 1, 2019
CompletedJanuary 27, 2021
January 1, 2021
7 months
April 24, 2019
January 25, 2021
Conditions
Outcome Measures
Primary Outcomes (1)
VO2 max
Maximum oxygen consumption using the Bruce Protocol
90 minutes after baseline
Secondary Outcomes (3)
Gastrointestinal symptoms questionnaire
Baseline, 90 minutes, 110 minutes
Blood glucose
Baseline, 90 minutes, 110 minutes
Blood lactate
Baseline, 90 minutes, 110 minutes
Study Arms (3)
Placebo of calcium
PLACEBO COMPARATORParticipants will consume 250 mg of calcium
Rhodiola
EXPERIMENTALParticipants will consume 250 mg of Rhodiola
Rhodiola and Cordyceps
EXPERIMENTALParticipants will consume a combination of 250 mg of Rhodiola and 225 mg of Cordyceps
Interventions
Ingestion of 250 mg of Rhodiola and 225 mg of Cordyceps
Eligibility Criteria
You may qualify if:
- Body Mass Index between 18.5 and 35 kg/m\^2
- Non-smoking (assessed by Health History Questionnaire)
- English-speaking
- Regular participation in physical activity (\>4 hours per week)
You may not qualify if:
- Medical conditions that prohibit physical activity (assessed by Health History Questionnaire)
- Pregnant women or women expecting/trying to become pregnant
- BMI greater than or equal to 35 kg/m\^2
- Current smoker (assessed by Health History Questionnaire)
Contact the study team to confirm eligibility.
Sponsors & Collaborators
Study Sites (1)
California Polytechnic State University
San Luis Obispo, California, 93407, United States
Study Officials
- PRINCIPAL INVESTIGATOR
Todd Hagobian, PhD
California Polytechnic State University-San Luis Obispo
Study Design
- Study Type
- interventional
- Phase
- not applicable
- Allocation
- RANDOMIZED
- Masking
- TRIPLE
- Who Masked
- PARTICIPANT, INVESTIGATOR, OUTCOMES ASSESSOR
- Purpose
- BASIC SCIENCE
- Intervention Model
- CROSSOVER
- Sponsor Type
- OTHER
- Responsible Party
- PRINCIPAL INVESTIGATOR
- PI Title
- Principal Investigator
Study Record Dates
First Submitted
April 24, 2019
First Posted
April 29, 2019
Study Start
May 1, 2019
Primary Completion
December 1, 2019
Study Completion
December 1, 2019
Last Updated
January 27, 2021
Record last verified: 2021-01
Data Sharing
- IPD Sharing
- Will not share