Role of Ultrasound Imaging in Diagnosis of Juvenile Idiopathic Arthritis

NCT04178837 | Unknown

• 1 other identifier: Us in JIA
• Study Type: observational
• Target: 33
• Locations: 0 countries
• Sites: N/A

Brief Summary

Juvenile idiopathic arthritis (JIA) is the most common chronic rheumatic disease of childhood and an important cause of acquired disability in children . Despite the heterogeneity, all forms of JIA are characterized by prolonged synovial inflammation that can cause cartilage and bone damage, with severe impairment of physical function and impact on the quality of life. The presence of joint involvement in JIA may be expressed by ultrasonography findings such as synovial proliferation, effusion, cartilage thinning and bone erosions. US has demonstrated higher sensitivity in detecting synovitis compared to clinical examination MSUS is commonly regarded as a very useful tool in children, as outlined by the results of recent national and international surveys among pediatric rheumatologists .For most of the respondents, MSUS owned particular relevance for the ability to detect subclinical synovitis and to improve the classification of patients in JIA subtypes, as guidance to intraarticular corticosteroid injections and for capturing early articular damage. In addition, some specific joints were considered as most suited to be studied by MSUS, specifically the midfoot, the ankle, the hip, the wrist, the small joints of hands and feet. .

Conditions

Juvenile Idiopathic Arthritis

Outcome Measures

Primary Outcomes (1)

• Role of Ultrasound imaging in diagnosis of juvenile idiopathic arthritis

  Role of Ultrasound imaging in diagnosis activity \&exacepation of juvenile idiopathic arthritis

  2019_2021

Eligibility Criteria

• Age: 1 Year - 17 Years
• Sex: all
• Healthy Volunteers: Yes
• Age Groups: Child (0-17)
• Sampling Method: Probability Sample

Study Population

children with any type of Juvenile Idiopathic Arthritis

You may qualify if:

• Age between 1-17 years only.
• Both sexes.
• children with any type of Juvenile Idiopathic Arthritis

You may not qualify if:

• Age above 17years.
• Children with arthritis of known cause.

Sponsors & Collaborators

• Assiut University: lead

MeSH Terms

Conditions

Arthritis, Juvenile

Condition Hierarchy (Ancestors)

Arthritis; Joint Diseases; Musculoskeletal Diseases; Rheumatic Diseases; Connective Tissue Diseases; Skin and Connective Tissue Diseases; Autoimmune Diseases; Immune System Diseases

Study Design

• Study Type: observational
• Observational Model: COHORT
• Time Perspective: PROSPECTIVE
• Sponsor Type: OTHER
• Responsible Party: PRINCIPAL INVESTIGATOR
• PI Title: asmaa mohammed abd elhameed ali (amaeali)

Study Record Dates

• First Submitted: November 25, 2019
• First Posted: November 26, 2019
• Study Start: February 24, 2020
• Primary Completion: November 30, 2020
• Study Completion: November 30, 2021
• Last Updated: February 11, 2020

Record last verified: 2020-02