NCT04164771

Brief Summary

Aerobic training is essential for maintaining and improving physical performance and has a positive effect on physiological functions as well as anthropometric characteristics. It also has positive effect on cardiovascular health and carries a number of beneficial effects on the whole body functions and systems. Aerobic training can also decrease the risk of heart disease in the individual's life.The Moringa leaves are the rich source of minerals, vitamins and other essential phytochemicals. Moringa leave have found to be very effective in many disease particularly diabetic, blood pressure, dyslipidemia and cancer.

Trial Health

35
At Risk

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Trial has exceeded expected completion date
Enrollment
120

participants targeted

Target at P50-P75 for not_applicable

Timeline
Completed

Started Feb 2020

Shorter than P25 for not_applicable

Status
unknown

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

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Study Timeline

Key milestones and dates

First Submitted

Initial submission to the registry

November 7, 2019

Completed
8 days until next milestone

First Posted

Study publicly available on registry

November 15, 2019

Completed
3 months until next milestone

Study Start

First participant enrolled

February 1, 2020

Completed
2 months until next milestone

Primary Completion

Last participant's last visit for primary outcome

April 1, 2020

Completed
3 months until next milestone

Study Completion

Last participant's last visit for all outcomes

July 1, 2020

Completed
Last Updated

December 18, 2019

Status Verified

December 1, 2019

Enrollment Period

2 months

First QC Date

November 7, 2019

Last Update Submit

December 16, 2019

Conditions

Keywords

Aerobic trainingMoringaCardioprotection

Outcome Measures

Primary Outcomes (1)

  • Positive effect of aerobic training and Moringa Oleifera on dyslipidemia and cardiac endurance

    Change in level of HDL, LDL and triglyceride, impact on cardiac endurance

    6 weeks

Study Arms (4)

Moringa Group

EXPERIMENTAL

Participants will receive 5-7g of moringa diet daily for 6 weeks.

Other: Aerobic training and Moringa Oleifera

Aerobic training Group

EXPERIMENTAL

Participants will receive 5-7g of moringa diet daily and will do 30 minutes of aerobic training daily for 6 weeks.

Other: Aerobic training and Moringa Oleifera

Moringa and Aerobic training

EXPERIMENTAL

Participants will do 30 minutes of aerobic training daily for 6 weeks

Other: Aerobic training and Moringa Oleifera

Control Group (T4)

NO INTERVENTION

Participants will not recieve any treatment

Interventions

Aerobic exercises/training refers to any type of rhythmic, continuous physical activities that use large group of muscles like walking, running, cycling, and swimming consuming additional amount of energy while Moringa Oleifera a plant from the family Moringacea, its products are used as a health supplement introduced in Africa and south Asian countries to cure many diseases and improve health status

Aerobic training GroupMoringa GroupMoringa and Aerobic training

Eligibility Criteria

Age20 Years - 50 Years
Sexmale(Gender-based eligibility)
Healthy VolunteersYes
Age GroupsAdult (18-64)

You may qualify if:

  • Healthy and no medical conditions.
  • LDL level should be 160-189 mg/dl
  • HDL level should be \< 40 mg/dl
  • Tri glyceride level should be 200-499 mg/dl
  • Total cholesterol level should be \> 200 mg/dl).
  • Beep Test score should be less than 10.5 or less than 40% vo2 max

You may not qualify if:

  • Any disease condition as anemia, physical injuries, chronic disease
  • Not capable of doing aerobic training

Contact the study team to confirm eligibility.

Sponsors & Collaborators

MeSH Terms

Conditions

Dyslipidemias

Condition Hierarchy (Ancestors)

Lipid Metabolism DisordersMetabolic DiseasesNutritional and Metabolic Diseases

Study Officials

  • Naseer Ahmed, Ph.D

    Agha Khan Hospital

    PRINCIPAL INVESTIGATOR

Central Study Contacts

Naseer Ahmed, Ph.D

CONTACT

Javeria Farooq, M.Phil

CONTACT

Study Design

Study Type
interventional
Phase
not applicable
Allocation
RANDOMIZED
Masking
NONE
Purpose
HEALTH SERVICES RESEARCH
Intervention Model
PARALLEL
Sponsor Type
OTHER
Responsible Party
PRINCIPAL INVESTIGATOR
PI Title
Assistant Professor

Study Record Dates

First Submitted

November 7, 2019

First Posted

November 15, 2019

Study Start

February 1, 2020

Primary Completion

April 1, 2020

Study Completion

July 1, 2020

Last Updated

December 18, 2019

Record last verified: 2019-12

Data Sharing

IPD Sharing
Will not share