Analysis of Overtime in Soccer

NCT04159194 | Completed

• 1 other identifier: SOCCER-OVERTIME-UTH 2019
• Study Type: interventional
• Target: 20
• Locations: 1 country
• Sites: 1

Brief Summary

A randomized, two-trial (placebo vs. supplement consumption), cross-over, double-blind, repeated measures design will be applied to study i) the performance, metabolic and inflammatory overload of overtime in soccer and ii) how carbohydrate supplementation affects recovery following a football match with overtime. The study will be performed during a brake of the in-season period to mimic a real life setting. A 10-day washout period will be utilized between trials.

Conditions

Metabolic Stress

Keywords

soccer; overtime; performance; recovery

Outcome Measures

Primary Outcomes (15)

• Measurement of countermovement jump height

  Change from baseline to 90 minutes and 120 minutes of the game.

• Measurement of maximal sprinting speed over 10 meters

  10-m sprinting speed will be assessed on the soccer field by utilizing light cells

  Change from baseline to 90 minutes and 120 minutes of the game.

• Measurement of maximal sprinting speed over 30 meters

  30-m sprinting speed will be assessed on the soccer field by utilizing light cells

  Change from baseline to 90 minutes and 120 minutes of the game.

• Measurement of the capacity to perform repeated sprints

  5 x 30m repeated maximal sprints will be performed with 30 sec rest in between. Speed will be recorded by utilizing light cells.

  Change from baseline to 90 minutes and 120 minutes of the game.

• Measurement of isometric maximal voluntary contraction

  Isometric maximal voluntary contraction will be assessed on an isokinetic dynamometer

  At baseline

• Measurement of total protein content

  Total protein content will be assessed on muscle biopsy samples

  Change from baseline to 90 minutes and 120 minutes of the game.

• Measurement of muscle glycogen content

  Muscle glycogen content will be assessed on muscle biopsy samples

  Change from baseline to 90 minutes and 120 minutes of the game.

• Measurement of muscle phosphocreatine content

  Muscle phosphocreatine levels will be assessed on muscle biopsy samples

  Change from baseline to 90 minutes and 120 minutes of the game.

• Measurement of muscle lactate concentration

  Muscle lactate concentration will be assessed on muscle biopsy samples

  Change from baseline to 90 minutes and 120 minutes of the game.

• Measurement of Na+ - K+ ATPase levels

  Muscle Na+ - K+ ATPase levels will be assessed on muscle biopsy samples

  Change from baseline to 90 minutes and 120 minutes of the game.

• Measurement of creatine kinase activity

  Creatine kinase activity will be measured on blood samples

  Change from baseline to 90 minutes and 120 minutes of the game.

• Measurement of C-reactive protein levels

  C-reactive protein levels will be measured on blood samples

  Change from baseline to 90 minutes and 120 minutes of the game.

• Measurement of leukocyte counts

  Leukocyte counts will be measured on blood samples

  Change from baseline to 90 minutes and 120 minutes of the game.

• Measurement of Interleukin-6 levels

  Interleukin-6 levels will be measured on blood samples

  Change from baseline to 90 minutes and 120 minutes of the game.

• Measurement of Tumor necrosis factor - α levels

  Tumor necrosis factor - α levels will be measured on blood samples

  Change from baseline to 90 minutes and 120 minutes of the game.

Secondary Outcomes (3)

• Measurement of reactive strength index

  At baseline

• Measurement of blood lactate concentration

  Change from baseline to 90 minutes and 120 minutes of the game.

• Measurement of glucose concentration in blood

  Change from baseline to 90 minutes and 120 minutes of the game.

Study Arms (2)

Normal CHO

ACTIVE COMPARATOR

Other: Control Diet

High CHO

EXPERIMENTAL

Other: Experimental Diet

Interventions

Control Diet OTHER

Players during the control trial will be instructed to maintain their normal food intake (\~55% CHO) and the type and amount of ingested food will be recorded.

Normal CHO

Experimental Diet OTHER

The experimental diet will be administered by the investigators after M1, daily for the next 48 hours (three main meals, i.e. breakfast, lunch, and dinner, and snacks such as energy bars and raisins), and before M2 (breakfast and lunch)

High CHO

Eligibility Criteria

• Age: 20 Years - 26 Years
• Sex: male
• Healthy Volunteers: Yes
• Age Groups: Adult (18-64)

You may qualify if:

• competitive level for ≥4 years (≥5 training sessions/week, ≥1 match/week)
• no recent history of febrile illness, muscle lesions, lower limb trauma, and metabolic diseases
• no use of ergogenic supplements and medication (for ≥6 prior to the study)
• non-smokers

You may not qualify if:

• recent history of febrile illness, muscle lesions, lower limb trauma, and metabolic diseases
• use of ergogenic supplements and medication (for ≥6 prior to the study)
• smoking
• competitive level for \< 4 years

Sponsors & Collaborators

• University of Thessaly: lead

Study Sites (1)

University of Thessaly, School of Physical Education and Sports Science

Trikala, 42100, Greece

Location

Related Publications (2)

• Ermidis G, Mohr M, Jamurtas AZ, Draganidis D, Poulios A, Papanikolaou K, Vigh-Larsen JF, Loules G, Sovatzidis A, Nakopoulou T, Tsimeas P, Douroudos II, Papadopoulos C, Papadimas G, Rosvoglou A, Liakou C, Deli CK, Georgakouli K, Chatzinikolaou A, Krustrup P, Fatouros IG. Recovery during Successive 120-min Football Games: Results from the 120-min Placebo/Carbohydrate Randomized Controlled Trial. Med Sci Sports Exerc. 2024 Jun 1;56(6):1094-1107. doi: 10.1249/MSS.0000000000003398. Epub 2024 Jan 30.

  PMID: 38306312 DERIVED

• Mohr M, Ermidis G, Jamurtas AZ, Vigh-Larsen JF, Poulios A, Draganidis D, Papanikolaou K, Tsimeas P, Batsilas D, Loules G, Batrakoulis A, Sovatzidis A, Nielsen JL, Tzatzakis T, Deli CK, Nybo L, Krustrup P, Fatouros IG. Extended Match Time Exacerbates Fatigue and Impacts Physiological Responses in Male Soccer Players. Med Sci Sports Exerc. 2023 Jan 1;55(1):80-92. doi: 10.1249/MSS.0000000000003021. Epub 2022 Aug 12.

  PMID: 35977104 DERIVED

Study Officials

• Ioannis G Fatouros, Prof

  University of Thessaly

  PRINCIPAL INVESTIGATOR

Study Design

• Study Type: interventional
• Phase: not applicable
• Allocation: RANDOMIZED
• Masking: DOUBLE
• Who Masked: PARTICIPANT, INVESTIGATOR
• Purpose: BASIC SCIENCE
• Intervention Model: CROSSOVER
• Sponsor Type: OTHER
• Responsible Party: PRINCIPAL INVESTIGATOR
• PI Title: Professor

Study Record Dates

• First Submitted: September 10, 2019
• First Posted: November 12, 2019
• Study Start: September 30, 2019
• Primary Completion: October 17, 2019
• Study Completion: January 30, 2022
• Last Updated: April 18, 2023

Record last verified: 2019-09

Locations

GR (1)