NCT04155827

Brief Summary

Overweight and Obesity is a growing health problem worldwide. Lifestyle changes such as decreased physical activity, increased sedentary behaviour and unhealthy eating habits has contribute to this problem. According to World Health Organization (2016), more than 1.9 billion adults aged 18 years and older were overweight (39% of men and 40% of women).Regular exercise is the key contributor to energy expenditure and is essential for energy balance and weight control. Interval training (IT) has been commonly used for decades with purpose to improve body health and reduce weight loss and this exercise differs from the conventional aerobic exercise and endurance exercise as IT typically involves repeated bouts of relatively intense exercise interspersed by periods of lower- intensity effort or complete rest for recovery. One of the most common type of IT is sprint interval training (SIT). SIT involves 'supramaximal' effort (\>100% VO2max) work bouts, traditionally structured as four to six 30s all-out effort and each round separated by 4 minutes of recovery period of a low intensity exercise. Potential physiological adaptation of SIT are highlighted by various studies reporting cardiovascular, skeletal muscle adaptations, increase fat oxidation that facilitate increases in both aerobic and anaerobic performance. In addition, SIT is able to improve maximal rate of oxygen consumption (VO2max), at the same time improving the peripheral vascular structure and function, enzymes of fat metabolism and increases insulin sensitivity. Previous SIT studies have included young healthy men and women, healthy obese young women, all of which have shown that SIT is effective for fat loss and improvement of some health parameters. However, whether SIT protocol is equally effective in improving the anthropometric measures in men and women remain unknown.

Trial Health

87
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
35

participants targeted

Target at P25-P50 for not_applicable

Timeline
Completed

Started Feb 2020

Shorter than P25 for not_applicable

Geographic Reach
1 country

1 active site

Status
completed

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

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Study Timeline

Key milestones and dates

First Submitted

Initial submission to the registry

November 4, 2019

Completed
3 days until next milestone

First Posted

Study publicly available on registry

November 7, 2019

Completed
3 months until next milestone

Study Start

First participant enrolled

February 4, 2020

Completed
10 months until next milestone

Primary Completion

Last participant's last visit for primary outcome

November 16, 2020

Completed
7 days until next milestone

Study Completion

Last participant's last visit for all outcomes

November 23, 2020

Completed
Last Updated

November 24, 2020

Status Verified

November 1, 2020

Enrollment Period

10 months

First QC Date

November 4, 2019

Last Update Submit

November 22, 2020

Conditions

Outcome Measures

Primary Outcomes (5)

  • BMI for change

    At baseline (before intervention begin) and post training (end of 6 weeks).

  • Waist Circumference for change

    At baseline (before intervention begin) and post training (end of 6 weeks).

  • Total Fat % for change

    At baseline (before intervention begin) and post training (end of 6 weeks).

  • Lean Muscle Mass for change

    At baseline (before intervention begin) and post training (end of 6 weeks).

  • skin Fold Measurement for change

    At baseline (before intervention begin) and post training (end of 6 weeks).

Study Arms (2)

SIT for males

EXPERIMENTAL
Other: SIT

SIT for females

EXPERIMENTAL
Other: SIT

Interventions

SITOTHER

Sprint interval training of 4\*4, with 30 seconds of all out workout followed by 4 minutes of active recovery for 4 cycles.

SIT for femalesSIT for males

Eligibility Criteria

Age18 Years - 25 Years
Sexall(Gender-based eligibility)
Gender Eligibility DetailsBoth genders (male \& female) will be equally recruited.
Healthy VolunteersYes
Age GroupsAdult (18-64)

You may qualify if:

  • BMI≧23kg/m2(WHO for Asia-Pacific region)
  • No history of metabolic, hormonal, orthopedic, or cardiovascular diseases
  • No current use of prescribed medication including oral contraception

You may not qualify if:

  • Contraindications to physical activity assessed by Physical Activity Readiness Questionnaire-PAR-Q
  • Undergoes any surgical or hormone treatment

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

Universiti Tunku Abdul Rahman

Kajang, Selangor, 43000, Malaysia

Location

MeSH Terms

Conditions

OverweightObesity

Condition Hierarchy (Ancestors)

OvernutritionNutrition DisordersNutritional and Metabolic DiseasesBody WeightSigns and SymptomsPathological Conditions, Signs and Symptoms

Study Officials

  • Imtiyaz Ali Mir

    Universiti Tunku Abdul Rahman

    PRINCIPAL INVESTIGATOR

Study Design

Study Type
interventional
Phase
not applicable
Allocation
NON RANDOMIZED
Masking
SINGLE
Who Masked
OUTCOMES ASSESSOR
Purpose
TREATMENT
Intervention Model
PARALLEL
Sponsor Type
OTHER
Responsible Party
PRINCIPAL INVESTIGATOR
PI Title
Principal Investigator

Study Record Dates

First Submitted

November 4, 2019

First Posted

November 7, 2019

Study Start

February 4, 2020

Primary Completion

November 16, 2020

Study Completion

November 23, 2020

Last Updated

November 24, 2020

Record last verified: 2020-11

Data Sharing

IPD Sharing
Will not share

Locations