NCT04147897

Brief Summary

Randomized control trial examining two mHealth intervention strategies.

Trial Health

87
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
299

participants targeted

Target at P75+ for not_applicable schizophrenia

Timeline
Completed

Started Jun 2020

Typical duration for not_applicable schizophrenia

Geographic Reach
1 country

8 active sites

Status
completed

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

First Submitted

Initial submission to the registry

October 14, 2019

Completed
18 days until next milestone

First Posted

Study publicly available on registry

November 1, 2019

Completed
8 months until next milestone

Study Start

First participant enrolled

June 16, 2020

Completed
4.3 years until next milestone

Primary Completion

Last participant's last visit for primary outcome

September 16, 2024

Completed
Same day until next milestone

Study Completion

Last participant's last visit for all outcomes

September 16, 2024

Completed
1.2 years until next milestone

Results Posted

Study results publicly available

November 24, 2025

Completed
Last Updated

November 24, 2025

Status Verified

November 1, 2025

Enrollment Period

4.3 years

First QC Date

October 14, 2019

Results QC Date

September 8, 2025

Last Update Submit

November 10, 2025

Conditions

Outcome Measures

Primary Outcomes (7)

  • Patient Health Questionnaire (PHQ)-9

    The Patient Health Questionnaire (PHQ)-9 is the major depressive disorder (MDD) module of the full PHQ. Total scores range from 0-27. Higher scores represent more severe symptoms.

    0,3,6 months

  • Generalized Anxiety Disorder-7 (GAD-7)

    The Generalized Anxiety Disorder-7 (GAD-7) measures generalized anxiety disorder symptoms. GAD-7 total score ranges from 0 to 21. Higher scores represent more severe symptoms.

    0,3,6 months

  • Insomnia Severity Index (ISI)

    The Insomnia Severity Index (ISI) is a brief screening assessment tool designed to evaluate insomnia. Total scores range from 0-28. Higher scores represent more severe symptoms.

    0,3,6 months

  • Green Paranoid Thoughts Scale- Part B

    The Green Paranoid Thoughts Scale (GPTS)- part B measures ideas of persecution. Scores range from 16-80. Higher scores represent more severe symptoms.

    0,3,6 months

  • Symptom Check List (SCL-9)

    The Symptom Check List-9 (SCL-9) is a brief version of the SCL-90, which aims to evaluate a broad range of psychological problems and symptoms of psychopathology. Total scores are calculated as sum of all responses. Total sum scores range from 0-36. Higher scores mean more severe symptoms.

    0,3,6 months

  • Hamilton Program for Schizophrenia Voices Questionnaire (HPSVQ)

    A 9-item measure specifically designed to quantify characteristics of auditory hallucinations including frequency, negative content, loudness, duration, interference with life, distress, impact on self-appraisal, and compliance with commands. Total score is a sum of all 9 items. Total HPSVQ scores range from 0-36. Higher scores mean more severe symptoms.

    0,3,6 Months

  • Illness Management and Recovery Scales (IMRS)

    The Illness Management and Recovery Scales (IMRS) measure illness management and recovery. Scoring is a sum of all responses ranging from 15-75. Higher scores mean less severe symptoms.

    0,3,6 months

Study Arms (2)

Internal Facilitation

ACTIVE COMPARATOR

mHealth specialist is a trained clinician embedded in the clinical team offering the mHealth intervention, FOCUS.

Device: FOCUS

External Facilitation

ACTIVE COMPARATOR

mHealth specialist is a trained clinician external to the clinical team offering the mHealth intervention, FOCUS.

Device: FOCUS

Interventions

FOCUSDEVICE

FOCUS is a self management mHealth application for people with serious mental illness.

External FacilitationInternal Facilitation

Eligibility Criteria

Age18 Years - 100 Years
Sexall
Healthy VolunteersNo
Age GroupsAdult (18-64), Older Adult (65+)

You may qualify if:

  • Chart diagnosis of SSD (i.e., schizophrenia, schizoaffective disorder, schizotypal disorder, delusional disorder, or schizophreniform disorder;
  • years or older;
  • English-speaking;
  • Own a smartphone that can support FOCUS and active data plan.

You may not qualify if:

  • Used FOCUS in the past;
  • Plan to move or discontinue services at participating clinics in the upcoming 6 months.

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (8)

Cascade Mental Health Care

Chehalis, Washington, 98532, United States

Location

NEW Alliance Counseling Services

Colville, Washington, 99114, United States

Location

Compass Health

Everett, Washington, 98201, United States

Location

Valley Cities

Federal Way, Washington, 98003, United States

Location

Peninsula Behavioral Health

Port Angeles, Washington, 98362, United States

Location

Sound Health

Seattle, Washington, 98125, United States

Location

Frontier Behavioral Health

Spokane, Washington, 99201, United States

Location

Comprehensive Healthcare

Yakima, Washington, 98902, United States

Location

MeSH Terms

Conditions

Schizophrenia

Condition Hierarchy (Ancestors)

Schizophrenia Spectrum and Other Psychotic DisordersMental Disorders

Results Point of Contact

Title
Dror Ben-Zeev, Professor
Organization
University of Washington

Study Officials

  • Dror Ben-Zeev, PhD

    University of Washington

    PRINCIPAL INVESTIGATOR

Publication Agreements

PI is Sponsor Employee
No
Restrictive Agreement
No

Study Design

Study Type
interventional
Phase
not applicable
Allocation
RANDOMIZED
Masking
SINGLE
Who Masked
OUTCOMES ASSESSOR
Purpose
TREATMENT
Intervention Model
PARALLEL
Sponsor Type
OTHER
Responsible Party
PRINCIPAL INVESTIGATOR
PI Title
Professor, School of Medicine: Psychiatry And Behavioral Sciences

Study Record Dates

First Submitted

October 14, 2019

First Posted

November 1, 2019

Study Start

June 16, 2020

Primary Completion

September 16, 2024

Study Completion

September 16, 2024

Last Updated

November 24, 2025

Results First Posted

November 24, 2025

Record last verified: 2025-11

Data Sharing

IPD Sharing
Will not share

Locations