Triple Procedure for Dense Cataractus Neovascular Glaucoma Patients
NVG
1 other identifier
interventional
12
1 country
1
Brief Summary
Background: One of the most difficult refractory glaucomas in treatment is the neovascular type and its association with dense cataract add to this difficulty. This study aimed to provide results of triple surgical treatment of such conditions. Methods: A total of 12 eyes of 12 patients with dense cataractus NVG patients were included in this study. The patients mean age was 57.25 ± 5.9 years. The mean pre-operative intraocular pressure (IOP) was 47.25 ± 4.04 mmHg with maximum antiglaucoma therapy. The mean best corrected distant visual acuities (BCDVA) in log MAR was 2.13 ± 0.38. All the patients received intra-vitreal injection of 1.25 mg (0.05 ml) bevacizumab followed by phacoemulsification, pars plana vitrectomy (PPV) including pan-retinal photocoagulation (PRP), and assisted trabeculectomy with Mitomycin c (MMC). Mean IOP and BCDVA changes were the main outcome results of this study.
Trial Health
Trial Health Score
Automated assessment based on enrollment pace, timeline, and geographic reach
participants targeted
Target at below P25 for not_applicable
Started Jul 2016
Typical duration for not_applicable
1 active site
Health score is calculated from publicly available data and should be used for screening purposes only.
Trial Relationships
Click on a node to explore related trials.
Study Timeline
Key milestones and dates
Study Start
First participant enrolled
July 1, 2016
CompletedPrimary Completion
Last participant's last visit for primary outcome
August 31, 2019
CompletedStudy Completion
Last participant's last visit for all outcomes
August 31, 2019
CompletedFirst Submitted
Initial submission to the registry
October 27, 2019
CompletedFirst Posted
Study publicly available on registry
October 29, 2019
CompletedJanuary 13, 2020
October 1, 2019
3.2 years
October 27, 2019
January 10, 2020
Conditions
Outcome Measures
Primary Outcomes (2)
BCDVA
Best corrected distant visual acuity
2 years
IOP
Intra-ocular pressure
2 years
Secondary Outcomes (1)
Post-operative complications
2 years
Study Arms (1)
Neovascular glaucoma
OTHERNeovascular glaucoma patients underwent triple procedure
Interventions
Eligibility Criteria
You may qualify if:
- The study included patients with uncontrolled angle closure dense cataractus NVG with maximum tolerated anti-glaucoma medications.
You may not qualify if:
- Excluded from this study eyes that had previous anti-glaucoma procedures, silicone oil filled eyes, previous buckle surgery or Conjunctival scaring from any cause, eyes with clear crystalline lens or faint cataract, eyes with corneal opacity, and eyes with visual acuity less than hand motion with good perception of light.
Contact the study team to confirm eligibility.
Sponsors & Collaborators
- Minia Universitylead
Study Sites (1)
Minia University
Minya, 61519, Egypt
Related Publications (1)
Moharram HM, Abd-Elhamid Mehany Elwan S, Nassar MM, Abdelkader MF. Triple Procedure for Dense Cataractous Neovascular Glaucoma Patients. J Ophthalmol. 2020 Jun 21;2020:1251203. doi: 10.1155/2020/1251203. eCollection 2020.
PMID: 32655940DERIVED
MeSH Terms
Conditions
Interventions
Condition Hierarchy (Ancestors)
Intervention Hierarchy (Ancestors)
Study Officials
- STUDY CHAIR
Hossam M Moharram, MD
Minia University
Study Design
- Study Type
- interventional
- Phase
- not applicable
- Allocation
- NA
- Masking
- NONE
- Purpose
- TREATMENT
- Intervention Model
- SINGLE GROUP
- Sponsor Type
- OTHER
- Responsible Party
- PRINCIPAL INVESTIGATOR
- PI Title
- Assistant professor of ophthalmology
Study Record Dates
First Submitted
October 27, 2019
First Posted
October 29, 2019
Study Start
July 1, 2016
Primary Completion
August 31, 2019
Study Completion
August 31, 2019
Last Updated
January 13, 2020
Record last verified: 2019-10
Data Sharing
- IPD Sharing
- Will share
- Shared Documents
- CSR
- Time Frame
- 2 years
- Access Criteria
- study results
Results of the study