NCT02258113

Brief Summary

The aim of this study is to measure visual acuity, contrast sensitivity and visual field by SAP-method using a novel device Ocusweep compared to currently widely used methods. Addition to that, the aim is to validate a novel perimetry method (Visual Search Test, VST) which is based on reaction times in visual decision- making task, where the subject is allowed to move eyes and where the fixation is verified by the subject himself in contrast to standard automatic perimetry (SAP) where prolonged stationary fixation and external fixation monitoring apparatus is required. Reaction-time based visual field device Ocusweep is compared to generally used SAP methods. Those tests will be done for healthy volunteers and for persons with diagnosed eye or brain disease. Ocusweep OcuRT vision based choice reaction time test is validated for test repeatability and compared to Trail Making Test (TMT), Useful Field of View (UFOV) and Vienna Test System (VTS) reaction time tests. To evaluate the ability to detect unreliable results, OcuRT test is also done under cognitive load and with instructions to cheat the test.

Trial Health

43
At Risk

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Trial has exceeded expected completion date
Enrollment
600

participants targeted

Target at P75+ for not_applicable

Timeline
Completed

Started Nov 2014

Longer than P75 for not_applicable

Geographic Reach
1 country

1 active site

Status
unknown

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

First Submitted

Initial submission to the registry

September 30, 2014

Completed
7 days until next milestone

First Posted

Study publicly available on registry

October 7, 2014

Completed
25 days until next milestone

Study Start

First participant enrolled

November 1, 2014

Completed
7.1 years until next milestone

Primary Completion

Last participant's last visit for primary outcome

December 1, 2021

Completed
1.1 years until next milestone

Study Completion

Last participant's last visit for all outcomes

December 31, 2022

Completed
Last Updated

June 17, 2020

Status Verified

June 1, 2020

Enrollment Period

7.1 years

First QC Date

September 30, 2014

Last Update Submit

June 15, 2020

Conditions

Outcome Measures

Primary Outcomes (1)

  • Visual acuity

    Visual acuity is measured as logMAR unit at the one visit for each patient using a novel reaction-time based visual field device and comparable method.

    One visit per one patient (1h/visit)

Secondary Outcomes (3)

  • Contrast sensitivity

    One visit per one patient (1h/visit)

  • Reaction time visual field

    One visit per one patient (1h/visit)

  • Vision based choice reaction time

    One visit per one test subject (1h/visit)

Study Arms (1)

LEA numbers, Pelli-Robson, Octopus

OTHER

Comparable generally used method for measuring visual acuity, contrast sensitivity and visual field.

Device: OcusweepDevice: Ocusweep OcuRT

Interventions

OcusweepDEVICE

A novel reaction-time based visual field device.

LEA numbers, Pelli-Robson, Octopus

Vision based choice reaction time test method

LEA numbers, Pelli-Robson, Octopus

Eligibility Criteria

Age18 Years - 95 Years
Sexall
Healthy VolunteersYes
Age GroupsAdult (18-64), Older Adult (65+)

You may qualify if:

  • Healthy volunteers
  • Persons suffering diagnosed eye disease
  • Persons suffering diagnosed brain disease

You may not qualify if:

  • No diabetes
  • Only one diagnosed disease

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

Ocuspecto Oy

Turku, 20100, Finland

RECRUITING

MeSH Terms

Conditions

Vision Disorders

Condition Hierarchy (Ancestors)

Sensation DisordersNeurologic ManifestationsNervous System DiseasesEye DiseasesSigns and SymptomsPathological Conditions, Signs and Symptoms

Central Study Contacts

Markku Leinonen, Dr

CONTACT

Jaakko Suominen, MSc

CONTACT

Study Design

Study Type
interventional
Phase
not applicable
Allocation
NA
Masking
NONE
Purpose
HEALTH SERVICES RESEARCH
Intervention Model
SINGLE GROUP
Sponsor Type
INDUSTRY
Responsible Party
SPONSOR

Study Record Dates

First Submitted

September 30, 2014

First Posted

October 7, 2014

Study Start

November 1, 2014

Primary Completion

December 1, 2021

Study Completion

December 31, 2022

Last Updated

June 17, 2020

Record last verified: 2020-06

Locations