Level of FeNO in Chinese Asthma Patients

NCT04125316 | Completed

• 1 other identifier: FeNO_study_protocol V1
• Study Type: observational
• Target: 132
• Locations: 1 country
• Sites: 1

Brief Summary

This study aims to assess the level of FeNO in Chinese asthma patients with respect to the different levels of asthma control over 1 year.

Conditions

Asthma

Keywords

Asthma

Outcome Measures

Primary Outcomes (1)

• the level of FeNO

  to assess the level of FeNO in Chinese asthma patients with respect to the different levels of asthma control over a period of 1 year.

  1 year

Secondary Outcomes (1)

• FeNO and risk of asthma exacerbation

  1 year

Study Arms (1)

Asthma

Asthma patients

Other: Observation, no intervention

Interventions

Observation, no intervention OTHER

Observational study, no intervnetion

Also known as: No intervention

Asthma

Eligibility Criteria

• Age: 18 Years+
• Sex: all
• Healthy Volunteers: No
• Age Groups: Adult (18-64), Older Adult (65+)
• Sampling Method: Non-Probability Sample

Study Population

Asthma patients attending clinic at the Prince of Wales Hospital in Hong Kong

You may qualify if:

• Chinese subjects aged between 18 and 90 years, and
• Have a diagnosis of asthma according to The Global Initiative for Asthma (GINA) guideline 2019. Asthma is defined as those with a consistent history and prior documented evidence of variable airflow obstruction, with evidence of an increase in FEV1 greater than 12% or 200 mL following bronchodilator or bronchial hyperresponsiveness on bronchial provocation testing, when stable.

You may not qualify if:

• Patients with respiratory diseases with other known respiratory diseases including chronic obstructive pulmonary disease, bronchiectasis, tuberculosis (TB)-destroyed lung parenchyma, history of lung resection and lung cancer
• Individuals older than 40 years with a smoking history of more than 10 pack-years
• Patients currently randomized in other clinical studies
• Pregnant women

Sponsors & Collaborators

• Chinese University of Hong Kong: lead

Study Sites (1)

The Chinese University of Hong Kong

Hong Kong, Hong Kong

Location

MeSH Terms

Conditions

Asthma

Interventions

Observation

Condition Hierarchy (Ancestors)

Bronchial Diseases; Respiratory Tract Diseases; Lung Diseases, Obstructive; Lung Diseases; Respiratory Hypersensitivity; Hypersensitivity, Immediate; Hypersensitivity; Immune System Diseases

Intervention Hierarchy (Ancestors)

Methods; Investigative Techniques

Study Officials

• David Hui, MD

  Chinese University of Hong Kong

  STUDY DIRECTOR

Study Design

• Study Type: observational
• Observational Model: CASE CONTROL
• Time Perspective: PROSPECTIVE
• Sponsor Type: OTHER
• Responsible Party: PRINCIPAL INVESTIGATOR
• PI Title: Honorary Clinical Associate Professor

Study Record Dates

• First Submitted: September 27, 2019
• First Posted: October 14, 2019
• Study Start: October 15, 2019
• Primary Completion: December 30, 2022
• Study Completion: December 31, 2022
• Last Updated: February 8, 2023

Record last verified: 2023-02

Data Sharing

• IPD Sharing: Will not share

Locations

HK (1)