The Development of Reward Response to Food in Infancy

NCT04114123 | Completed

• 1 other identifier: HUM00164906
• Study Type: observational
• Target: 1,166
• Locations: 1 country
• Sites: 1

Brief Summary

In this study the researchers want to learn more about reward-driven eating behavior in children ages 2 to 18 months. The researchers hope to use this knowledge to help inform obesity prevention programs.

Conditions

Eating Behavior

Keywords

Reward-driven Eating; Infant; Maternal

Outcome Measures

Primary Outcomes (1)

• Association of trajectory membership and body mass index z-score (BMIz)

  Trajectory membership could be "wanting", "salience", or "liking"

  Time Frame: 24 months

Other Outcomes (8)

• Association of reward-driven eating component wanting with maternal and infant characteristics

  Up to 18 months

• Association of reward-driven eating component salience with maternal and infant characteristics

  Up to 18 months

• Association of reward-driven eating component liking with maternal and infant characteristics

  Up to 18 months

Study Arms (2)

Longitudinal

The researchers will be evaluating baseline indicators of wanting salience and liking between 2 and 6 month olds, with the goal of following up with these families at 24 months and beyond by reviewing the dyads' medical charts. The researchers will also examine direct and indirect associations between reward-driven eating, and maternal and infant characteristics and infant weight-for-length.

Cross-sectional

The researchers will as the mother to answer questionnaires and participate in up to two video taped behavioral protocols when the infant is 6 months old.

Eligibility Criteria

• Age: 18 Years+
• Sex: all
• Healthy Volunteers: Yes
• Age Groups: Adult (18-64), Older Adult (65+)
• Sampling Method: Non-Probability Sample

Study Population

The researchers will enroll infants and their mothers (age limit given is for minimum age for mothers) from the community and from sites allowed and approved by the IRB like pediatric clinics and childcare centers. They will be recruiting participants living within a 50 mile radius around Ann Arbor, MI.

You may qualify if:

• Baby is alive
• Baby is 6 to 16 weeks old at time of enrollment
• Baby and mother receive care at Michigan Medicine, and specifically:
• Baby was born at Michigan medicine
• Baby has had a 2 month well child check
• Mother received prenatal care at Michigan Medicine
• Mother has a linked patient profile to baby's profile
• Baby has a length and weight measurement on record
• Mother is English speaking

You may not qualify if:

• Baby is a foster child
• Baby was still in hospital 4 days after birth
• Baby has severe perinatal or neonatal medical problems
• Baby has severe developmental delays
• Multiple births
• For the Cross Sectional:
• Enrolled in longitudinal arm of study
• Eligible to complete all three protocols (Two Oatmeal and Reaching) as per protocol screeners
• Baby is alive
• Baby is 5 to 7 months old at the time of enrollment
• Mother is biological mother
• Mother is legal guardian
• Mother is English speaking
• Baby had severe perinatal or neonatal medical problems
• Baby currently has severe medical problems

Sponsors & Collaborators

• University of Michigan: lead
• American Heart Association: collaborator

Study Sites (1)

University of Michigan

Ann Arbor, Michigan, 48109, United States

Location

MeSH Terms

Conditions

Feeding Behavior

Condition Hierarchy (Ancestors)

Behavior, Animal; Behavior

Study Officials

• Julie Lumeng

  University of Michigan

  PRINCIPAL INVESTIGATOR

Study Design

• Study Type: observational
• Observational Model: COHORT
• Time Perspective: OTHER
• Sponsor Type: OTHER
• Responsible Party: PRINCIPAL INVESTIGATOR
• PI Title: Thomas P Borders Family Research Professor of Child Behavior and Development, Professor of Pediatrics, Associate Dean for Research, Medical School, Professor of Nutritional Sciences

Study Record Dates

• First Submitted: October 1, 2019
• First Posted: October 3, 2019
• Study Start: November 13, 2019
• Primary Completion: June 19, 2024
• Study Completion: June 19, 2024
• Last Updated: November 26, 2024

Record last verified: 2024-11

Data Sharing

• IPD Sharing: Will share
• Time Frame: Data submitted to Deep Blue Data will be reviewed after 10 years to determine if a dataset should be retained and will be subject to further, periodic, reviews thereafter.
• Access Criteria: All data in the Deep Blue Data repository are available to anyone for download without restriction.

Locations

US (1)