Prevalence of Bronchiectasis in COPD Patients

NCT04101448 | Unknown

• 1 other identifier: AssiutU7
• Study Type: observational
• Target: 100
• Locations: 1 country
• Sites: 1

Brief Summary

The identification of bronchiectasis in COPD has been defined as a different clinical COPD phenotype with greater symptomatic severity, more frequent chronic bronchial infection and exacerbations, and poor prognosis. A causal association has not yet been proven, but it is biologically plausible that COPD, and particularly the infective and exacerbator COPD phenotypes, could be the cause of bronchiectasis without any other known etiology, beyond any mere association or comorbidity.

Conditions

Bronchiectasis; Chronic Obstruct Airways Disease; Prognosis

Keywords

Bronchiectasis; COPD; Prevalence; Prognosis

Outcome Measures

Primary Outcomes (1)

• Prevalence of Bronchiectasis in COPD

  percentage of bronchiectasis diagnosed by CT chest in COPD patients

  1 year

Secondary Outcomes (3)

• impact of bronchiectasis on COPD exacerbations

  1 year

• impact of bronchiectasis on COPD hospitalization

  1 year

• impact of bronchiectasis on COPD intensive care admission

  1 year

Study Arms (2)

Group A

COPD patients with bronchiectasis

Other: prevalence

Group B

COPD patients without bronchiectasis

Other: prevalence

Interventions

prevalence OTHER

percentage of bronchectasis in COPD and its effect as prognostic measure

Group A; Group B

Eligibility Criteria

• Age: 18 Years - 80 Years
• Sex: all
• Age Groups: Adult (18-64), Older Adult (65+)
• Sampling Method: Non-Probability Sample

Study Population

COPD patients diagnosed based on GOLD criteria 2019 with chest CT finding of bronchiectasis

You may qualify if:

• COPD patients based on GOLD 2019 criteria, stable or in exacerbation

You may not qualify if:

• acute pneumonia within 2 months
• malignancy
• congenital bronchiectasis ( immobile cilia syndrome, Kartagnar syndrome).
• Pregnancy

Sponsors & Collaborators

• Assiut University: lead

Study Sites (1)

AssiutU

Asyut, 71111, Egypt

RECRUITING

MeSH Terms

Conditions

Bronchiectasis; Pulmonary Disease, Chronic Obstructive

Interventions

Prevalence

Condition Hierarchy (Ancestors)

Bronchial Diseases; Respiratory Tract Diseases; Lung Diseases, Obstructive; Lung Diseases; Chronic Disease; Disease Attributes; Pathologic Processes; Pathological Conditions, Signs and Symptoms

Intervention Hierarchy (Ancestors)

Morbidity; Vital Statistics; Data Collection; Epidemiologic Methods; Investigative Techniques; Demography; Population Characteristics; Epidemiologic Measurements; Public Health; Environment and Public Health

Central Study Contacts

Aliae Mohamed-Hussein

CONTACT

01222302352; aliaehussein@gmail.com

Study Design

• Study Type: observational
• Observational Model: COHORT
• Time Perspective: PROSPECTIVE
• Sponsor Type: OTHER
• Responsible Party: PRINCIPAL INVESTIGATOR
• PI Title: Professor of Pulmonology

Study Record Dates

• First Submitted: September 22, 2019
• First Posted: September 24, 2019
• Study Start: September 30, 2019
• Primary Completion: September 1, 2020
• Study Completion: September 30, 2020
• Last Updated: September 24, 2019

Record last verified: 2019-09

Locations

EG (1)