NCT04100369

Brief Summary

In polytrraumatized patients, Does hyperglycaemia on admission increase the risk of morbidity and mortality compared to polytraumatised patients with normal blood glucose level ?

Trial Health

35
At Risk

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Trial has exceeded expected completion date
Enrollment
100

participants targeted

Target at P50-P75 for all trials

Timeline
Completed

Started Jan 2020

Shorter than P25 for all trials

Status
unknown

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

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Study Timeline

Key milestones and dates

First Submitted

Initial submission to the registry

September 20, 2019

Completed
4 days until next milestone

First Posted

Study publicly available on registry

September 24, 2019

Completed
3 months until next milestone

Study Start

First participant enrolled

January 1, 2020

Completed
8 months until next milestone

Primary Completion

Last participant's last visit for primary outcome

September 1, 2020

Completed
4 months until next milestone

Study Completion

Last participant's last visit for all outcomes

December 31, 2020

Completed
Last Updated

September 24, 2019

Status Verified

September 1, 2019

Enrollment Period

8 months

First QC Date

September 20, 2019

Last Update Submit

September 20, 2019

Conditions

Keywords

shock , poly trauma , serum lactate

Outcome Measures

Primary Outcomes (1)

  • Admission blood glucose as a predictor of morbidity and mortality in polytraumatized patients

    to investigate the admission blood glucose level as a predictor of morbidity and mortality in poly traumatized patients

    baseline

Secondary Outcomes (1)

  • Admission blood glucose as a predictor of morbidity and mortality in polytraumatized patients

    baseline

Interventions

laboratoryDIAGNOSTIC_TEST

Arm

Eligibility Criteria

Age18 Years+
Sexall
Age GroupsAdult (18-64), Older Adult (65+)
Sampling MethodNon-Probability Sample
Study Population

using blood glucose as an easy and a rapid predictor of morbidity and mortality in poly traumatized patients

You may qualify if:

  • Age \>= 18 years
  • Polytrauma ISS \>= 18
  • Recent polytrauma patients who are directly transferred by the ambulance from the scene of accident to assiut university hospital and did not receive resuscitative measurements in another hospital

You may not qualify if:

  • known co-morbidities affecting blood glucose level like :
  • Pregnant women
  • Diabetic patients

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Related Publications (2)

  • Laird AM, Miller PR, Kilgo PD, Meredith JW, Chang MC. Relationship of early hyperglycemia to mortality in trauma patients. J Trauma. 2004 May;56(5):1058-62. doi: 10.1097/01.ta.0000123267.39011.9f.

    PMID: 15179246BACKGROUND
  • Lichtveld RA, Panhuizen IF, Smit RB, Holtslag HR, van der Werken C. Predictors of Death in Trauma Patients who are Alive on Arrival at Hospital. Eur J Trauma Emerg Surg. 2007 Feb;33(1):46-51. doi: 10.1007/s00068-007-6097-6. Epub 2007 Feb 27.

    PMID: 26815974BACKGROUND

MeSH Terms

Conditions

Shock

Condition Hierarchy (Ancestors)

Pathologic ProcessesPathological Conditions, Signs and Symptoms

Study Officials

  • Hossam Abubeih, ass.prof

    Assiut University

    STUDY DIRECTOR
  • fasil adam, prof

    Assiut University

    STUDY DIRECTOR

Central Study Contacts

tamer armanious, MD

CONTACT

Study Design

Study Type
observational
Observational Model
COHORT
Time Perspective
PROSPECTIVE
Target Duration
3 Weeks
Sponsor Type
OTHER
Responsible Party
PRINCIPAL INVESTIGATOR
PI Title
Assistant Lecturer

Study Record Dates

First Submitted

September 20, 2019

First Posted

September 24, 2019

Study Start

January 1, 2020

Primary Completion

September 1, 2020

Study Completion

December 31, 2020

Last Updated

September 24, 2019

Record last verified: 2019-09