Platelets to Albumin Ratio for Prediction of Acute Kidney Injury in Patients Admitted to the Intensive Care Unit

NCT06554977 | Not Yet Recruiting

• 1 other identifier: Aki in icu patients
• Study Type: observational
• Target: 140
• Locations: 0 countries
• Sites: N/A

Brief Summary

To evaluate the role of platelet to albumin ratio to detect Acute kidney injury in patients admitted to intensive care

Conditions

Platelets/Albumin and Aki

Outcome Measures

Primary Outcomes (1)

• Detect relation between platelets to albumin ratio for prediction of transient or persistent AKI in ICU patients

  T he included patients will be divided into two groups according to the optimal cut-off value of PAR: high-PAR group (≥ 7.2), low-PAR group (\< 7.2). Number of patients is 140

  2years

Secondary Outcomes (1)

• Effect of the cause of ICU admission on platelets to albumin ratio and persistent AKI

  2years

Study Arms (2)

Patient with Aki

acute kidney injury that will be divided into transient and persistent Aki according to follow up within 48hr and 72hr with kidney function (urea \& creatine)

Other: Laboratory

Non Aki patients

Other: Laboratory

Interventions

Laboratory OTHER

CBC Kidney function (Urea, creatine) Platelets to albumin ratio Albumin /creatine ratio CRP Urine analysis Abdominal us Kidney function , CBC , Albumin will be done at the time of admission i

Non Aki patients; Patient with Aki

Eligibility Criteria

• Age: 18 Years+
• Sex: all
• Age Groups: Adult (18-64), Older Adult (65+)
• Sampling Method: Non-Probability Sample

Study Population

Patients admitted to icu number of patients 140

You may qualify if:

• (1) Patient admitted to ICU whatever the cause ( 2) KDIGO-AKI criteria based on serum creatinine in the first 48 h of their ICU. admission

You may not qualify if:

• less than 18-year-old at first admission to ICU; (3) more than 10% of personal data was missing; (4) patients with repeated ICU admissions; (5) patients without serum creatinine measures between 48 and 72 h after the diagnosis of AKI (6) pregnant women . (7) patient known chronic kidney disease. (8) Patient with End stage renal disease

Sponsors & Collaborators

• Assiut University: lead

MeSH Terms

Interventions

Laboratories

Intervention Hierarchy (Ancestors)

Non-Medical Public and Private Facilities; Health Facilities; Health Care Facilities Workforce and Services

Study Design

• Study Type: observational
• Observational Model: CASE CONTROL
• Time Perspective: CROSS SECTIONAL
• Sponsor Type: OTHER
• Responsible Party: PRINCIPAL INVESTIGATOR
• PI Title: Physician

Study Record Dates

• First Submitted: July 26, 2024
• First Posted: August 15, 2024
• Study Start: September 1, 2024
• Primary Completion (Estimated): September 1, 2026
• Study Completion (Estimated): September 1, 2027
• Last Updated: August 15, 2024

Record last verified: 2024-07