Role of Pleural Fluid Attenuation Value on CT as a Diagnostic Tool in Traumatic Hemothorax

NCT04098185 | Unknown

• 1 other identifier: CT in traumatic hemothorax
• Study Type: observational
• Target: 100
• Locations: 0 countries
• Sites: N/A

Brief Summary

To define the potential role of pleural fluid attenuation value determined on computed tomography (CT) for diagnosis of traumatic hemothorax and differentiate it from other pleural effusion.

Conditions

Hemothorax; Traumatic

Outcome Measures

Primary Outcomes (1)

• Role of pleural fluid attenuation value measurement on CT as a diagnostic tool for traumatic hemothorax

  Measurements of pleural effusion attenuation value on CT to diagnose traumatic hemothorax and differentiate it from other types of pleural effusion.

  from 1 December 2019 to 1 December 2020

Interventions

CT DEVICE

Non-contrast Multidetector Computed Tomography will be done for all patients using 16 or 64 MDCT scanner. Standard scanning parameters of chest CT are used with slice thickness 5 mm, 120kv and automated mAs.The evaluation of pleural effusion attenuation will be done using the average measure of 3 slices with greatest amount of fluid. A region of interest (ROI) is placed for measurement of Hounsfield unit values, where pleural fluid is observed to be most intense and the density values of the pleural fluid and of the aorta are quantitatively measured in the same section with taking care not to involve adjacent ribs, lung parenchyma or areas of pleural thickening.

Eligibility Criteria

• Age: 18 Years - 75 Years
• Sex: all
• Healthy Volunteers: No
• Age Groups: Adult (18-64), Older Adult (65+)
• Sampling Method: Non-Probability Sample

Study Population

All patients above 18 years old with history of blunt chest trauma and hemodynamically unstable.

You may qualify if:

• All patients above 18 years old
• History of blunt chest trauma
• Having mild to moderate effusion
• CT chest within 1st 24 hours of trauma
• Patients underwent tube thoracostomy or thoracocentesis

You may not qualify if:

• Patients in need of emergency transfer to surgery.
• Hemodynamically stable.
• Patients with penetrating trauma.
• Patients with no need for tube thoracostomy or thoracocentesis.
• Patients with minimal effusion.
• Pregnant females.

Sponsors & Collaborators

• Assiut University: lead

Related Publications (12)

• Sridhar S, Raptis C, Bhalla S. Imaging of Blunt Thoracic Trauma. Semin Roentgenol. 2016 Jul;51(3):203-14. doi: 10.1053/j.ro.2015.12.002. Epub 2015 Dec 18. No abstract available.

  PMID: 27287951 BACKGROUND

• Meyer DM. Hemothorax related to trauma. Thorac Surg Clin. 2007 Feb;17(1):47-55. doi: 10.1016/j.thorsurg.2007.02.006.

  PMID: 17650696 BACKGROUND

• Sangster GP, Gonzalez-Beicos A, Carbo AI, Heldmann MG, Ibrahim H, Carrascosa P, Nazar M, D'Agostino HB. Blunt traumatic injuries of the lung parenchyma, pleura, thoracic wall, and intrathoracic airways: multidetector computer tomography imaging findings. Emerg Radiol. 2007 Oct;14(5):297-310. doi: 10.1007/s10140-007-0651-8. Epub 2007 Jul 11.

  PMID: 17623115 BACKGROUND

• Miller LA. Chest wall, lung, and pleural space trauma. Radiol Clin North Am. 2006 Mar;44(2):213-24, viii. doi: 10.1016/j.rcl.2005.10.006.

  PMID: 16500204 BACKGROUND

• Mirvis SE. Imaging of acute thoracic injury: the advent of MDCT screening. Semin Ultrasound CT MR. 2005 Oct;26(5):305-31. doi: 10.1053/j.sult.2005.08.001.

  PMID: 16274001 BACKGROUND

• Hooper C, Lee YC, Maskell N; BTS Pleural Guideline Group. Investigation of a unilateral pleural effusion in adults: British Thoracic Society Pleural Disease Guideline 2010. Thorax. 2010 Aug;65 Suppl 2:ii4-17. doi: 10.1136/thx.2010.136978. No abstract available.

  PMID: 20696692 BACKGROUND

• Romero M, Bachler P. Pseudo-hemothorax at computed tomography due to residual contrast media. Clin Imaging. 2014 May-Jun;38(3):333-5. doi: 10.1016/j.clinimag.2014.01.004. Epub 2014 Jan 16.

  PMID: 24559752 BACKGROUND

• Kaewlai R, Avery LL, Asrani AV, Novelline RA. Multidetector CT of blunt thoracic trauma. Radiographics. 2008 Oct;28(6):1555-70. doi: 10.1148/rg.286085510.

  PMID: 18936021 BACKGROUND

• Gordon CE, Feller-Kopman D, Balk EM, Smetana GW. Pneumothorax following thoracentesis: a systematic review and meta-analysis. Arch Intern Med. 2010 Feb 22;170(4):332-9. doi: 10.1001/archinternmed.2009.548.

  PMID: 20177035 BACKGROUND

• Liu F, Huang YC, Ng YB, Liang JH. Differentiatepleural effusion from hemothorax after bluntchest trauma; comparison of computed tomography attenuation values. Journal of AcuteMedicine 2016; 6: 1-6.

  BACKGROUND

• Cummings KW, Javidan-Nejad C, Bhalla S. Multidetector computed tomography of nonosseous thoracic trauma. Semin Roentgenol. 2014 Apr;49(2):134-42. doi: 10.1053/j.ro.2014.01.002. Epub 2014 Jan 28. No abstract available.

  PMID: 24836489 BACKGROUND

• Bolus D, Morgan D, Berland L. Effective use of the Hounsfield unit in the age of variable energy CT. Abdom Radiol (NY). 2017 Mar;42(3):766-771. doi: 10.1007/s00261-017-1052-4.

  PMID: 28132073 BACKGROUND

MeSH Terms

Conditions

Hemothorax

Condition Hierarchy (Ancestors)

Pleural Diseases; Respiratory Tract Diseases; Hemorrhage; Pathologic Processes; Pathological Conditions, Signs and Symptoms

Central Study Contacts

Ghada Abdelazem Abdelbary, Dr

CONTACT

00201098815249; khalid.kamal1987@yahoo.com

Eman proffesor Abo Elhamd, Prof Dr

CONTACT

00201001980793; dr.eman_08@yahoo.com

Study Design

• Study Type: observational
• Observational Model: COHORT
• Time Perspective: PROSPECTIVE
• Sponsor Type: OTHER
• Responsible Party: PRINCIPAL INVESTIGATOR
• PI Title: Resident of Diagnostic Radiology

Study Record Dates

• First Submitted: September 19, 2019
• First Posted: September 23, 2019
• Study Start: December 1, 2019
• Primary Completion: December 1, 2020
• Study Completion: January 1, 2021
• Last Updated: September 24, 2019

Record last verified: 2019-09