Skull Bon Variations in Patient with Congenital Unilatral Choanal Atresia
Associated Radiological Variations in the Skull Bones in Patients with Cong: Unilateral Choanal Atresia
1 other identifier
observational
30
0 countries
N/A
Brief Summary
Identify skull bone Associated Anomalies in patients with cngenital unilatral choanal atresia
Trial Health
Trial Health Score
Automated assessment based on enrollment pace, timeline, and geographic reach
participants targeted
Target at below P25 for all trials
Started Apr 2025
Health score is calculated from publicly available data and should be used for screening purposes only.
Trial Relationships
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Study Timeline
Key milestones and dates
First Submitted
Initial submission to the registry
March 6, 2025
CompletedFirst Posted
Study publicly available on registry
March 24, 2025
CompletedStudy Start
First participant enrolled
April 1, 2025
CompletedPrimary Completion
Last participant's last visit for primary outcome
April 1, 2026
CompletedStudy Completion
Last participant's last visit for all outcomes
May 1, 2026
CompletedMarch 24, 2025
March 1, 2025
1 year
March 6, 2025
March 20, 2025
Conditions
Outcome Measures
Primary Outcomes (1)
Radiological Variations in Skull Bones in Patients with Congenital Unilateral Choanal Atresia: A Cross-Sectional Study"
Degree and Type of Skull Bone Anomalies Presence and extent of bony abnormalities in the skull base (e.g., sphenoid bone asymmetry, pterygoid plate thickening) Degree of nasal cavity narrowing and choanal obstruction Associated maxillofacial bone abnormalities (e.g., septal deviation, maxillary sinus hypoplasia) 2\. Measurement of Specific Skull Bone Changes Thickness of the atretic plate (bony vs. membranous) Asymmetry of pterygoid plates (measured in mm) Deviation angle of the nasal septum (in degrees) Orbital and maxillary asymmetry
10_12 month
Interventions
Thickened Medial Pterygoid Plates In bony atresia, excessive thickening of the medial pterygoid plates is common. Narrowing or Fusion of the Posterior Choanae Complete bony or membranous obstruction at the choanal opening. Abnormal Sphenoid Bone Development Hypoplasia or deformity in the sphenoid sinus, affecting adjacent structures. Vomer Deviation or Hypertrophy The vomer bone is often displaced or abnormally thickened, contributing to obstruction. Abnormal Development of the Hard Palate
Eligibility Criteria
The study population will include patients diagnosed with congenital unilateral choanal atresia (CUCA). The inclusion and exclusion criteria will ensure a well-defined and homogenous group for analysis.
You may qualify if:
- clinical diagnosis of Congenital Unilateral Choanal Atresia
You may not qualify if:
- Patients with severe craniofacial syndromes
Contact the study team to confirm eligibility.
Sponsors & Collaborators
Related Publications (1)
Kwong KM. Current Updates on Choanal Atresia. Front Pediatr. 2015 Jun 9;3:52. doi: 10.3389/fped.2015.00052. eCollection 2015.
PMID: 26106591BACKGROUND
Study Officials
- PRINCIPAL INVESTIGATOR
Ahmed Ragab Sayed, Lecturer
Central Study Contacts
Mohamed Azam Abdelrazek, Professor
CONTACT
Study Design
- Study Type
- observational
- Observational Model
- COHORT
- Time Perspective
- PROSPECTIVE
- Sponsor Type
- OTHER
- Responsible Party
- PRINCIPAL INVESTIGATOR
- PI Title
- Principal investigator
Study Record Dates
First Submitted
March 6, 2025
First Posted
March 24, 2025
Study Start
April 1, 2025
Primary Completion
April 1, 2026
Study Completion
May 1, 2026
Last Updated
March 24, 2025
Record last verified: 2025-03