NCT04095481

Brief Summary

Post-approval study for the Obalon Navigation/Touch System (NTS)

Trial Health

43
At Risk

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Trial has exceeded expected completion date
Enrollment
1,600

participants targeted

Target at P75+ for all trials

Timeline
Completed

Started Dec 2019

Typical duration for all trials

Geographic Reach
1 country

2 active sites

Status
unknown

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

First Submitted

Initial submission to the registry

August 26, 2019

Completed
24 days until next milestone

First Posted

Study publicly available on registry

September 19, 2019

Completed
3 months until next milestone

Study Start

First participant enrolled

December 3, 2019

Completed
3.5 years until next milestone

Primary Completion

Last participant's last visit for primary outcome

May 30, 2023

Completed
Same day until next milestone

Study Completion

Last participant's last visit for all outcomes

May 30, 2023

Completed
Last Updated

December 23, 2019

Status Verified

December 1, 2019

Enrollment Period

3.5 years

First QC Date

August 26, 2019

Last Update Submit

December 19, 2019

Conditions

Outcome Measures

Primary Outcomes (2)

  • Esophageal Inflation

    Percentage of esophageal Inflation during the balloon administrations using the Obalon NTS.

    Up to 20 Weeks

  • System Success

    Percentage of appropriate inflation in the stomach with the use of NTS only (without radiography) or correctly determining failed balloon transit (device in the esophagus) as confirmed by endoscopic removal

    Up to 20 Weeks

Study Arms (1)

Obalon NTS

Patients who commercially purchased the NTS Compatible Obalon Balloon System

Device: Obalon Navigation/Touch System

Interventions

The NTS Compatible Obalon Balloon System does NOT require the use of radiographic verification prior to the inflation of the intragastric balloon

Obalon NTS

Eligibility Criteria

Age22 Years+
Sexall
Healthy VolunteersYes
Age GroupsAdult (18-64), Older Adult (65+)
Sampling MethodProbability Sample
Study Population

Patients 22 years and older with a starting therapy BMI of 30.0-40.0 kg/m2 and who commercially purchased the Obalon Balloon device.

You may qualify if:

  • Ages 22 years and older
  • Starting or current therapy BMI of 30.0-40.0 kg/m2
  • Commercially purchased the Obalon Balloon Device

You may not qualify if:

  • Known history of structural or functional disorders of the esophagus that may impede passage of the device through the gastrointestinal tract or increase risk of esophageal damage during an endoscopic removal procedure, including, Barrett's esophagus, esophagitis, dysphagia, achalasia, stricture/stenosis, esophageal varices, esophageal diverticula, esophageal perforation or any other disorder of the esophagus.
  • Known history of structural or functional disorder of the esophagus, including any swallowing disorder, esophageal chest pain disorders, or drug refractory esophageal reflux symptoms.
  • Known history of structural or functional disorders of the stomach including, gastroparesis, gastric ulcer, chronic gastritis, gastric varices, hiatal hernia (\> 2 cm), cancer or any other disorder of the stomach.
  • Active implantable devices, such as a pacemaker of defibrillator, or with metal implants in the thoracic region.

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (2)

Ultimate Bariatrics - Flower Mound

Flower Mound, Texas, 75028, United States

RECRUITING

Ultimate Bariatrics - Fort Worth

Fort Worth, Texas, 76102, United States

RECRUITING

MeSH Terms

Conditions

Obesity

Condition Hierarchy (Ancestors)

OverweightOvernutritionNutrition DisordersNutritional and Metabolic DiseasesBody WeightSigns and SymptomsPathological Conditions, Signs and Symptoms

Central Study Contacts

Study Design

Study Type
observational
Observational Model
CASE ONLY
Time Perspective
PROSPECTIVE
Sponsor Type
INDUSTRY
Responsible Party
SPONSOR

Study Record Dates

First Submitted

August 26, 2019

First Posted

September 19, 2019

Study Start

December 3, 2019

Primary Completion

May 30, 2023

Study Completion

May 30, 2023

Last Updated

December 23, 2019

Record last verified: 2019-12

Locations