Abdominal Aortic Aneurysm Patients Remain at Risk for Delirium on the Surgical Ward After Intensive Care Unit Dismissal

NCT04080557 | Completed

• 1 other identifier: 305213JR
• Study Type: observational
• Target: 135
• Locations: 1 country
• Sites: 1

Brief Summary

The incidence of delirium following open abdominal aortic aneurysm (AAA) surgery is significant, with incidence rates ranging from 12 to 33%. The occurrence of delirium on the surgical ward after intensive care unit (ICU) dismissal in AAA patients remains unclear. Differences in outcomes between a delirium on the ICU and a delirium on the surgical ward have not been previously investigated. Delirium is a frequent complication in patients who underwent open AAA surgery. This study demonstrated that patients on the surgical ward remain at risk for developing a delirium after ICU dismissal. Physicians should therefore maintain a high level of awareness for delirium in AAA patients who return to the surgical ward after ICU dismissal. This simultaneously emphasises the necessity of delirium preventive measures and early recognition on the surgical ward in order to improve clinical outcomes.

Conditions

Delirium; AAA; Intensive Care Unit Delirium; Surgery--Complications; Surgery; Aortic Aneurysm, Abdominal

Keywords

delirium; intensive care unit; surgical ward; abdominal aortic aneurysm surgery

Outcome Measures

Primary Outcomes (1)

• the incidence of delirium

  The incidence of delirium on the ICU and on the ward

  between january 2013 and december 2018

Secondary Outcomes (1)

• mortality

  6 months and 12 months

Other Outcomes (5)

• Length of hospital stay

  Data on re-interventions, readmissions and survival were collected until February 2019.

• Length of ICU stay

  Data on re-interventions, readmissions and survival were collected until February 2019.

• Reoperations

  Data on re-interventions, readmissions and survival were collected until February 2019.

Study Arms (1)

AAA patients that went to the ICU postoperatively

An retrospective cohort study was conducted that included all patients treated electively for an abdominal aortic aneurysm (AAA) by open repair and patients undergoing emergency treatment for a ruptured AAA between 2013 and 2018.

Other: Surgery

Interventions

Surgery OTHER

All patients treated electively for an abdominal aortic aneurysm (AAA) by open repair and patients undergoing emergency treatment for a ruptured AAA between 2013 and 2018.

Also known as: Open abdominal aortic repair, Endovascular aortic repair

AAA patients that went to the ICU postoperatively

Eligibility Criteria

• Sex: all
• Healthy Volunteers: Yes
• Age Groups: Child (0-17), Adult (18-64), Older Adult (65+)
• Sampling Method: Non-Probability Sample

Study Population

A total of 135 patients were included in the study. Of these, 72 were treated for a ruptured abdominal aortic aneurysm and 63 were treated electively with open aortic repair.

You may qualify if:

• All patients treated electively for an abdominal aortic aneurysm (AAA) by open repair and patients undergoing emergency treatment for a ruptured AAA between 2013 and 2018.

You may not qualify if:

• Patients that did not survive surgery
• Patients that did not go to the intensive care unit postoperatively.

Sponsors & Collaborators

• Amphia Hospital: lead

Study Sites (1)

Amphia hospital

Breda, North Brabant, 4818CK, Netherlands

Location

MeSH Terms

Conditions

Delirium; Aortic Aneurysm, Abdominal

Interventions

Surgical Procedures, Operative; Endovascular Aneurysm Repair

Condition Hierarchy (Ancestors)

Confusion; Neurobehavioral Manifestations; Neurologic Manifestations; Nervous System Diseases; Signs and Symptoms; Pathological Conditions, Signs and Symptoms; Neurocognitive Disorders; Mental Disorders; Aortic Aneurysm; Aneurysm; Vascular Diseases; Cardiovascular Diseases; Aortic Diseases

Intervention Hierarchy (Ancestors)

Endovascular Procedures; Vascular Surgical Procedures; Cardiovascular Surgical Procedures; Blood Vessel Prosthesis Implantation; Vascular Grafting; Minimally Invasive Surgical Procedures; Prosthesis Implantation

Study Officials

• Lijckle van der Laan, MD, PhD

  Amphia hospital Breda, the Netherlands

  STUDY CHAIR

Study Design

• Study Type: observational
• Observational Model: COHORT
• Time Perspective: RETROSPECTIVE
• Sponsor Type: OTHER
• Responsible Party: PRINCIPAL INVESTIGATOR
• PI Title: Principal Investigator

Study Record Dates

• First Submitted: September 3, 2019
• First Posted: September 6, 2019
• Study Start: November 1, 2018
• Primary Completion: February 28, 2019
• Study Completion: February 28, 2019
• Last Updated: September 6, 2019

Record last verified: 2019-09

Locations

NL (1)