Role of Chest Sonography in Evaluation of Pleurodesis in Patients With Malignant Pleural Effusion
1 other identifier
observational
100
0 countries
N/A
Brief Summary
Thoracic ultrasonography easily detects the movement of the visceral pleura on the parietal pleura This sign is absent when pleurodesis is successful.
Trial Health
Trial Health Score
Automated assessment based on enrollment pace, timeline, and geographic reach
participants targeted
Target at P50-P75 for all trials
Started Sep 2019
Shorter than P25 for all trials
Health score is calculated from publicly available data and should be used for screening purposes only.
Trial Relationships
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Study Timeline
Key milestones and dates
First Submitted
Initial submission to the registry
August 28, 2019
CompletedFirst Posted
Study publicly available on registry
August 30, 2019
CompletedStudy Start
First participant enrolled
September 1, 2019
CompletedPrimary Completion
Last participant's last visit for primary outcome
September 1, 2019
CompletedStudy Completion
Last participant's last visit for all outcomes
September 1, 2020
CompletedAugust 30, 2019
August 1, 2019
Same day
August 28, 2019
August 29, 2019
Conditions
Outcome Measures
Primary Outcomes (1)
Evaluate and compare the outcome of pleurodisis by different modalities.
To compare chest sonographic findings versus Multislice CT findings in detecting endobronchial obstruction in patients with malignant pleural effusion
baseline
Interventions
Mindray dp1100 plus.
Eligibility Criteria
100 patients will be chosen at random for one year from the start of the study and will be recruited from chest out patient clinc and department Assiut University hospital which are eligible for this study
You may qualify if:
- Any patient with malignant pleural effusion who will undergo palliative treatment with insertion of intercostal tube.
You may not qualify if:
- Patients \<18 years old, unable to provide informed consent.
- Had an allergy or other contraindication to intrapleural pleurodesis.
- Had evidence of unexpandable lung believed by the responsible clinician to represent insufficient.
- pleural apposition that would preclude pleurodesis, and/or had an expected survival of\<1 month.
Contact the study team to confirm eligibility.
Sponsors & Collaborators
Related Publications (1)
Corcoran JP, Hallifax RJ, Mercer RM, Yousuf A, Asciak R, Hassan M, Piotrowska HE, Psallidas I, Rahman NM. Thoracic Ultrasound as an Early Predictor of Pleurodesis Success in Malignant Pleural Effusion. Chest. 2018 Nov;154(5):1115-1120. doi: 10.1016/j.chest.2018.08.1031. Epub 2018 Sep 20.
PMID: 30243566BACKGROUND
MeSH Terms
Interventions
Intervention Hierarchy (Ancestors)
Study Design
- Study Type
- observational
- Observational Model
- CASE ONLY
- Time Perspective
- PROSPECTIVE
- Sponsor Type
- OTHER
- Responsible Party
- PRINCIPAL INVESTIGATOR
- PI Title
- Principal investigator
Study Record Dates
First Submitted
August 28, 2019
First Posted
August 30, 2019
Study Start
September 1, 2019
Primary Completion
September 1, 2019
Study Completion
September 1, 2020
Last Updated
August 30, 2019
Record last verified: 2019-08
Data Sharing
- IPD Sharing
- Will not share