Umbilical Cord Length Index for Prediction of Cord Abnormalities Before Delivery

NCT03604887 | Completed

• 1 other identifier: UCLI
• Study Type: observational
• Target: 300
• Locations: 1 country
• Sites: 1

Brief Summary

The umbilical cord plays an essential role in intrauterine life. It is the pathway between mother, placenta and fetus during pregnancy and delivery. Complete cord occlusion often leads to fetal demise, while intermittent occlusion has been associated with intrauterine brain damage. Compression and vasospasm in utero are important factors in fetal distress. Nuchal Umbilical Cord can be diagnosed antepartum using ultrasound, but the complications are unpredictable and unpreventable

Conditions

Umbilical Cord Problem

Outcome Measures

Primary Outcomes (1)

• The sensitivity of "Umbilical cord length index" in diagnosis of long and short umbilical cords.

  Ultrasonographic scoring of umbilical cord length

  15 minutes

Study Arms (1)

study group

All pregnant women who will attend the labor unit during the study period will be invited to participate in the study.

Diagnostic Test: ultrasonography

Interventions

ultrasonography DIAGNOSTIC_TEST

Ultrasound evaluation will be done with transducer abdominal probe. The amount of amniotic fluid and umbilical cord sections will be determined by evaluating the images obtained from the sagittal plane in the ultrasound evaluations in the 4 abdominal quadrants. When the anatomical structure of the umbilical cord is considered, it is folded in amniotic fluid. The folds appear as umbilical cord rings, side-by-side at the sagittal sections. Scoring of "umbilical cord length index" * 1 point will be given for each quadrant where the umbilical cord was observed. * 0.5 point will be given for each umbilical cord ring in one quadrant. Every quadrant will be evaluated in this manner, and the total score will be calculated.

study group

Eligibility Criteria

• Sex: female
• Healthy Volunteers: No
• Age Groups: Child (0-17), Adult (18-64), Older Adult (65+)
• Sampling Method: Probability Sample

Study Population

Patients who are in labor will be followed up through regular fetal heart rate monitoring and clinically using partograph to monitor the progress of labor. Fetal heart rate changes and cases with abnormal progress of labor will be recorded. Mode of delivery either vaginal or cesarean will be noted. Those who are scheduled for elective CS will be evaluated during and after cesarean section.

You may qualify if:

• Singleton pregnancy.
• Pregnant ≥ 37 weeks gestation.
• Women who will accept to participate in the study

You may not qualify if:

• Preterm deliveries.
• Amniotic fluid abnormalities (oligohydramnios, polyhydramnios).
• Intrauterine growth retardation
• Early membrane rupture
• Women need urgent cesarean section.
• Multifetal gestation.
• Placenta previa.
• Fetuses with major congenital anomalies.
• Women with chronic maternal illness as hypertension

Sponsors & Collaborators

• Assiut University: lead

Study Sites (1)

Assiut Faculty of Medicine

Asyut, Egypt

Location

MeSH Terms

Interventions

Ultrasonography

Intervention Hierarchy (Ancestors)

Diagnostic Imaging; Diagnostic Techniques and Procedures; Diagnosis

Study Design

• Study Type: observational
• Observational Model: OTHER
• Time Perspective: CROSS SECTIONAL
• Sponsor Type: OTHER
• Responsible Party: PRINCIPAL INVESTIGATOR
• PI Title: Principal investigator

Study Record Dates

• First Submitted: July 21, 2018
• First Posted: July 30, 2018
• Study Start: March 1, 2019
• Primary Completion: December 1, 2020
• Study Completion: January 31, 2021
• Last Updated: April 23, 2021

Record last verified: 2021-04

Data Sharing

• IPD Sharing: Will not share

Locations

EG (1)