NCT04073446

Brief Summary

To evaluate programming modalities at various targets for focal foot, knee pain, and groin pain relief.

Trial Health

87
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
3

participants targeted

Target at below P25 for not_applicable chronic-pain

Timeline
Completed

Started Oct 2019

Typical duration for not_applicable chronic-pain

Geographic Reach
1 country

1 active site

Status
completed

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

First Submitted

Initial submission to the registry

July 23, 2019

Completed
1 month until next milestone

First Posted

Study publicly available on registry

August 29, 2019

Completed
2 months until next milestone

Study Start

First participant enrolled

October 31, 2019

Completed
1.9 years until next milestone

Primary Completion

Last participant's last visit for primary outcome

October 1, 2021

Completed
Same day until next milestone

Study Completion

Last participant's last visit for all outcomes

October 1, 2021

Completed
1.5 years until next milestone

Results Posted

Study results publicly available

March 29, 2023

Completed
Last Updated

March 29, 2023

Status Verified

December 1, 2022

Enrollment Period

1.9 years

First QC Date

July 23, 2019

Results QC Date

September 30, 2022

Last Update Submit

March 27, 2023

Conditions

Keywords

Spinal Cord StimulationChronic Pain

Outcome Measures

Primary Outcomes (1)

  • Change in Pain Intensity

    Change in pain intensity from Baseline to end of each Period (knee/foot). Pain scores are measured on a scale of 0 - 10 where 0 is no pain and 10 is maximum pain possible.

    up to 6 weeks

Study Arms (4)

Dorsal Column (DC) Perception

ACTIVE COMPARATOR

Use of DC Perception based programming

Device: Spinal Cord Stimulation

Dorsal Root (DR) Perception

ACTIVE COMPARATOR

Use of DR Perception based programming

Device: Spinal Cord Stimulation

Dorsal Root (DR) Sub-perception

ACTIVE COMPARATOR

Use of DR sub-perception based programming

Device: Spinal Cord Stimulation

Dorsal Column (DC) Sub-perception

ACTIVE COMPARATOR

Use of DC sub-perception based programming

Device: Spinal Cord Stimulation

Interventions

Patients eligible for SCS

Dorsal Column (DC) PerceptionDorsal Column (DC) Sub-perceptionDorsal Root (DR) PerceptionDorsal Root (DR) Sub-perception

Eligibility Criteria

Age18 Years+
Sexall
Healthy VolunteersNo
Age GroupsAdult (18-64), Older Adult (65+)

You may qualify if:

  • Average unilateral foot, or knee or groin pain intensity of 6 or greater on a 0-10 numerical rating scale at Baseline Visit based on 7-day average NRS score
  • Subject signed a valid, EC-approved informed consent form (ICF)
  • Willing and able to comply with all protocol-required procedures and assessments/evaluations
  • years of age or older when written informed consent is obtained

You may not qualify if:

  • Significant cognitive impairment at Screening that, in the opinion of the Investigator, would reasonably be expected to impair the study candidates to participate in the study
  • Participating (or intends to participate) in another drug or device clinical trial that may influence the data that will be collected for this study

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

AZ Nikolaas

Sint-Niklaas, Belgium

Location

MeSH Terms

Conditions

Chronic Pain

Interventions

Spinal Cord Stimulation

Condition Hierarchy (Ancestors)

PainNeurologic ManifestationsSigns and SymptomsPathological Conditions, Signs and Symptoms

Intervention Hierarchy (Ancestors)

Electric Stimulation TherapyTherapeuticsPhysical Therapy ModalitiesRehabilitation

Results Point of Contact

Title
Roshini Jain, Sr. Director Clinical Sciences
Organization
Boston Scientific

Study Officials

  • Roshini Jain

    Boston Scientific Corporation

    STUDY DIRECTOR

Publication Agreements

PI is Sponsor Employee
No
Restrictive Agreement
Yes

Study Design

Study Type
interventional
Phase
not applicable
Allocation
RANDOMIZED
Masking
DOUBLE
Who Masked
PARTICIPANT, OUTCOMES ASSESSOR
Purpose
TREATMENT
Intervention Model
CROSSOVER
Sponsor Type
INDUSTRY
Responsible Party
SPONSOR

Study Record Dates

First Submitted

July 23, 2019

First Posted

August 29, 2019

Study Start

October 31, 2019

Primary Completion

October 1, 2021

Study Completion

October 1, 2021

Last Updated

March 29, 2023

Results First Posted

March 29, 2023

Record last verified: 2022-12

Locations