NCT04231409

Brief Summary

Study to Demonstrate the Value of Fast-Acting Subperception (FAST) using the Spectra WaveWriter™ Spinal Cord Stimulator System in the Treatment of Chronic Pain

Trial Health

57
Monitor

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
41

participants targeted

Target at P25-P50 for not_applicable chronic-pain

Timeline
Completed

Started Nov 2019

Shorter than P25 for not_applicable chronic-pain

Geographic Reach
1 country

6 active sites

Status
terminated

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

Study Start

First participant enrolled

November 26, 2019

Completed
2 months until next milestone

First Submitted

Initial submission to the registry

January 14, 2020

Completed
4 days until next milestone

First Posted

Study publicly available on registry

January 18, 2020

Completed
9 months until next milestone

Primary Completion

Last participant's last visit for primary outcome

October 1, 2020

Completed
Same day until next milestone

Study Completion

Last participant's last visit for all outcomes

October 1, 2020

Completed
1.3 years until next milestone

Results Posted

Study results publicly available

January 24, 2022

Completed
Last Updated

January 24, 2022

Status Verified

January 1, 2022

Enrollment Period

10 months

First QC Date

January 14, 2020

Results QC Date

October 7, 2021

Last Update Submit

January 21, 2022

Conditions

Outcome Measures

Primary Outcomes (1)

  • Overall Pain Responder Rate

    Proportion of subjects with 50% or greater reduction from Baseline Visit in average overall pain intensity at 3 months post-randomization

    3 months post-randomization

Study Arms (2)

WaveWriter Settings

ACTIVE COMPARATOR

WaveWriter Programming

Device: Boston Scientific Spectra WaveWriter SCS System

Conventional Settings

ACTIVE COMPARATOR

Conventional Programming

Device: Boston Scientific Spectra WaveWriter SCS System

Interventions

The Spectra WaveWriter Spinal Cord Stimulator (SCS) System is indicated as an aid in the management of chronic intractable pain of the trunk and/or limbs, including unilateral or bilateral pain associated with the following: failed back surgery syndrome, Complex Regional Pain Syndrome (CRPS) Types I and II, intractable low back pain and leg pain.

Conventional SettingsWaveWriter Settings

Eligibility Criteria

Age22 Years+
Sexall
Healthy VolunteersNo
Age GroupsAdult (18-64), Older Adult (65+)

You may qualify if:

  • Chronic pain of the trunk and/or limbs for at least 6 months with back pain greater or equal to leg pain.
  • years of age or older at time of enrollment
  • Able to independently read and complete all questionnaires and assessments provided in English
  • Signed a valid, IRB-approved informed consent form (ICF) provided in English

You may not qualify if:

  • Any pain-related diagnosis or medical/psychological condition that, in the clinician's best judgment, might confound reporting of study outcomes
  • Significant cognitive impairment that, in the opinion of the Investigator, would reasonably be expected to impair the study candidate's ability to participate in the study
  • Breast-feeding or planning to get pregnant during the course of the study or not using adequate contraception
  • Participating, or intends to participate, in another clinical trial that may influence the data that will be collected for this study

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (6)

Center for Pain and Supportive Care

Phoenix, Arizona, 85028, United States

Location

Willis-Knighton River Cities Clinical Research Center

Shreveport, Louisiana, 71105, United States

Location

The Center for Clinical Research, LLC

Winston-Salem, North Carolina, 27103, United States

Location

Cleveland Clinic Foundation

Cleveland, Ohio, 44195, United States

Location

Pacific Sports and Spine, LLC

Eugene, Oregon, 97401, United States

Location

Precision Spine Care

Tyler, Texas, 75701, United States

Location

MeSH Terms

Conditions

Chronic Pain

Condition Hierarchy (Ancestors)

PainNeurologic ManifestationsSigns and SymptomsPathological Conditions, Signs and Symptoms

Results Point of Contact

Title
Roshini Jain, Sr. Director Clinical Sciences
Organization
Boston Scientific

Study Officials

  • Mark Wallace

    University of California, San Diego

    PRINCIPAL INVESTIGATOR

Publication Agreements

PI is Sponsor Employee
No
Restrictive Agreement
Yes

Study Design

Study Type
interventional
Phase
not applicable
Allocation
RANDOMIZED
Masking
NONE
Purpose
TREATMENT
Intervention Model
PARALLEL
Sponsor Type
INDUSTRY
Responsible Party
SPONSOR

Study Record Dates

First Submitted

January 14, 2020

First Posted

January 18, 2020

Study Start

November 26, 2019

Primary Completion

October 1, 2020

Study Completion

October 1, 2020

Last Updated

January 24, 2022

Results First Posted

January 24, 2022

Record last verified: 2022-01

Data Sharing

IPD Sharing
Will not share

Locations