Endoscopic Characterization of Colorectal Neoplasia With the Different Published Classifications

NCT04048447 | Completed

• 1 other identifier: SFED PROTOCOL
• Study Type: observational
• Target: 206
• Locations: 1 country
• Sites: 1

Brief Summary

Endoscopic characterization is now essential in front of a colorectal lesion to predict its histology and choose the best therapeutic strategy. Different classifications have been proposed to predict histology depending on the endoscopic aspect. Thus, the aspect of the shape of the lesion is described in the Paris classification, the aspect of the mucosal pattern in Kudo's classification and the vascular pattern in Sano's one. Recently, classifications combining several color and mucosal and vascular pattern criteria have been described as the NICE classification or even more recently the Japanese JNET classification. However, although the interest in combining the Paris, Sano and Kudo criteria has recently shown its interest, there was not yet an overall classification covering all the published criteria. We have created a synthetic classification called CONECCT grouping the different criteria for an initial educational purpose. We have demonstrated that this tool allows interns and gastroenterologists to progress in the histological prediction of colorectal lesions presented in the form of photo files. Nevertheless, comparative data of the performances of those different classifications to predict the histology and the concordance intra and inter-observer have never been published. To validate this CONECCT classification, we created this comparative study evaluating the endoscopic characterization performances of these different classifications in terms of histological prediction and intra- and interobserver concordance in a group of gastroenterologists with varying levels of expertise in front of colorectal lesions presented in the form of photographic records.

Conditions

Colorectal Neoplasia

Outcome Measures

Primary Outcomes (1)

• Evaluation of the interobserver Concordance of the CONECCT classification compared to the 6 other existing ones

  1 year

Eligibility Criteria

• Age: 18 Years - 90 Years
• Sex: all
• Age Groups: Adult (18-64), Older Adult (65+)
• Sampling Method: Non-Probability Sample

Study Population

Colic Neoplasia Patients

You may qualify if:

• The participants were gastroenterologist doctors (experts, general or internal).
• Lesions presented were resected endoscopically after completion of a picture file.
• Pathology available for presented lesions.
• Participants signed informed consent and voluntarily participated in the characterization of these 206 lesions.

You may not qualify if:

• None

Sponsors & Collaborators

• Hôpital Edouard Herriot: lead

Study Sites (1)

Edouard Herriot Hospital

Lyon, Auvergne-Rhône-Alpes, 69437, France

Location

Study Design

• Study Type: observational
• Observational Model: COHORT
• Time Perspective: PROSPECTIVE
• Sponsor Type: OTHER
• Responsible Party: PRINCIPAL INVESTIGATOR
• PI Title: Professor

Study Record Dates

• First Submitted: August 5, 2019
• First Posted: August 7, 2019
• Study Start: August 1, 2018
• Primary Completion: August 1, 2018
• Study Completion: August 1, 2019
• Last Updated: August 7, 2019

Record last verified: 2019-08

Locations

FR (1)