Effect of Knowledge on Vaccine Take-up in Adamawa State, Northeastern Nigeria

NCT04042246 | Completed

• 1 other identifier: TBDNA
• Study Type: interventional
• Target: 400
• Locations: 1 country
• Sites: 1

Brief Summary

Child immunization is not a one-time behavior; rather, it is a repeated behavior within a specific timeframe. Not only the low immunization, but also the dropout of immunization and the delayed immunization from the recommended immunization schedule are prevalent and high in Africa. The most common reason for the incomplete vaccination is that caregivers thought the children had already been fully immunized (44.8%), according to Nigeria Multiple Indicator Cluster Survey (MICS) conducted in 2016/2017. Caregivers' misconception of the complete immunization can be attributed to the complicated immunization schedule. In Nigeria, infants are supposed to receive 9 different types of vaccines at 5 different times within the first year since the births. To make things more complicated, the vaccine schedule changes over time; for example in Nigeria, the new vaccine, inactivated polio vaccine (IPV) was introduced in 2015 to be received at 14 weeks after births, and rotavirus vaccine and meningococcal A vaccine are scheduled for the introduction in 2019. In this complicated and rapidly-changing environment regarding vaccination schedule, the goal of the study is to improve the understanding of vaccination completion and children's vaccination status among caregivers, which can then lead to the improved rate of full vaccination among children. Objectives The main objectives of this study are to understand the impact of providing the general and tailored information on the vaccination schedule and vaccination status of women's children on the vaccine take-up. In this study, the investigators focus on women who has a child who is 12 months old or younger. Hypothesis The main hypothesis of this proposed study are as follows:

1. 1.Information on vaccination among caregivers: the general and tailored information on vaccination schedule and child's vaccination status, improves the knowledge on benefit and understanding of vaccination completion, vaccination schedule and the vaccination status of the children among caregivers
2. 2.Full immunization rate: through the improved knowledge level on the concept of vaccination completion and their children's vaccination status, the proposed study increases the full immunization rate among children

Conditions

Immunization; Infection; Educational Problems; Information Seeking Behavior

Outcome Measures

Primary Outcomes (2)

• Number of participants who have the accurate knowledge level of vaccination, as assessed by survey questionnaire

  The investigators will collect the information on respondents' knowledge on vaccination through surveys. The knowledge level is calculated from 5 questions: 1) the number of type of vaccines a child needs to receive before 12 months old, 2) the number of times a child needs to receive Pentavalent vaccine, 3) the last month when a child needs to receive Pentavalent vaccine, 4) the timing when a child needs to receive BCG vaccine, and 5) the number of clinic visits (at minimum) a child needs to make for complete vaccination. For each question, the score is 0 if wrong, or 1 if correct. The knowledge level scale ranges from 0 to 5, which is the total number of correct answers.

  2 weeks

• Number of participants who bring their children for the full vaccination, as assessed by the follow-up tracking survey at health clinics

  The investigators will collect the information on the actual vaccination status among respondents' children

  9 months

Study Arms (2)

Control

NO INTERVENTION

No intervention is implemented among Control

Treatment (Educational Information on Vaccination)

EXPERIMENTAL

Provide general and tailored information on vaccination and vaccination schedule at the end of the baseline survey

Behavioral: Information Provision

Interventions

Information Provision BEHAVIORAL

Provide the information on the importance of the vaccination and tailored vaccination schedule

Treatment (Educational Information on Vaccination)

Eligibility Criteria

• Sex: female
• Healthy Volunteers: Yes
• Age Groups: Child (0-17), Adult (18-64), Older Adult (65+)

You may qualify if:

• women with a child 12 months old or younger

You may not qualify if:

• exclude women who do not have a child 12 months or younger

Sponsors & Collaborators

• Harvard School of Public Health (HSPH): lead

Study Sites (1)

Jada Local Government Primary Health Care Development Agency

Jada, Adamawa, Nigeria

Location

Related Publications (12)

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  PMID: 28459105 BACKGROUND

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  PMID: 6150332 BACKGROUND

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• Powell-Jackson T, Fabbri C, Dutt V, Tougher S, Singh K. Effect and cost-effectiveness of educating mothers about childhood DPT vaccination on immunisation uptake, knowledge, and perceptions in Uttar Pradesh, India: A randomised controlled trial. PLoS Med. 2018 Mar 6;15(3):e1002519. doi: 10.1371/journal.pmed.1002519. eCollection 2018 Mar.

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  PMID: 26501228 BACKGROUND

• VanderEnde K, Gacic-Dobo M, Diallo MS, Conklin LM, Wallace AS. Global Routine Vaccination Coverage - 2017. MMWR Morb Mortal Wkly Rep. 2018 Nov 16;67(45):1261-1264. doi: 10.15585/mmwr.mm6745a2.

  PMID: 30439873 BACKGROUND

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  PMID: 29342498 BACKGROUND

MeSH Terms

Conditions

Infections; Information Seeking Behavior

Condition Hierarchy (Ancestors)

Communication; Behavior

Study Officials

• Ryoko Sato, Ph.D.

  Harvard School of Public Health (HSPH)

  PRINCIPAL INVESTIGATOR

Study Design

• Study Type: interventional
• Phase: not applicable
• Allocation: RANDOMIZED
• Masking: DOUBLE
• Who Masked: PARTICIPANT, CARE PROVIDER
• Purpose: HEALTH SERVICES RESEARCH
• Intervention Model: PARALLEL
• Sponsor Type: OTHER
• Responsible Party: PRINCIPAL INVESTIGATOR
• PI Title: Principal Investigator

Study Record Dates

• First Submitted: July 29, 2019
• First Posted: August 1, 2019
• Study Start: September 15, 2019
• Primary Completion: February 9, 2020
• Study Completion: February 9, 2020
• Last Updated: July 14, 2020

Record last verified: 2020-07

Data Sharing

• IPD Sharing: Will not share

Locations

NG (1)