The Effect of Dual Tasking on Physical and Cognitive Functions in Patients With Parkinson Disease

NCT03902990 | Completed

• 1 other identifier: 20181443
• Study Type: interventional
• Target: 45
• Locations: 1 country
• Sites: 1

Brief Summary

The ability of performing multi-tasking procedures is impaired in patients with Parkinson's disease. In this study, our goal was to detect the effects of dual-task training with treadmill training on walking and balance and to compare its effects on quality of life, cognitive functions and risk of fall, to treadmill training alone.

Conditions

Parkinson Disease

Keywords

dual task, treadmill, cognitive rehabilitation

Outcome Measures

Primary Outcomes (4)

• 10MWT

  10 Meter Walk Test on comfortable speed

  12 weeks

• 10MWT with cognitive tasks

  10 Meter Walk Test with cognitive tasks

  12 weeks

• MoCA

  Montreal Cognitive Assessment

  12 weeks

• TUG

  Timed Up and Go Test

  12 weeks

Secondary Outcomes (5)

• PDQ-39

  12 weeks

• FES-I

  12 weeks

• Stroop Test

  12 weeks

• FOGQ

  12 weeks

• Falls Diary

  4 weeks

Study Arms (3)

Dual task

EXPERIMENTAL

Treadmill training + cognitive tasks + standard exercise programme

Other: Dual task; Other: Treadmill Training; Other: Standard exercise programme

Single task

ACTIVE COMPARATOR

Treadmill training + standard exercise programme

Other: Treadmill Training; Other: Standard exercise programme

Control

ACTIVE COMPARATOR

Standard exercise programme

Other: Standard exercise programme

Interventions

Dual task OTHER

The patients in the dual task group received cognitive tasks during treadmill training sessions.

Dual task

Treadmill Training OTHER

Standard treadmill training

Dual task; Single task

Standard exercise programme OTHER

Standard exercise programme for Parkinson Disease

Control; Dual task; Single task

Eligibility Criteria

• Age: 18 Years - 75 Years
• Sex: all
• Healthy Volunteers: No
• Age Groups: Adult (18-64), Older Adult (65+)

You may qualify if:

• The patients with Idiopathic Parkinson Disease on medication who has
• Hoehn-Yahr 1-3
• Mini Mental Test score 20 and above
• Functional Ambulation Category 2 and above
• No changes in medication in last 3 months
• No rehabilitation programme in last 3 months

You may not qualify if:

• Diagnosis of Parkinsonism other than Idiopathic Parkinson Disease
• Global aphasia
• Severe cognitive dysfunction
• Other neurologic/orthopedic diseases
• Limiting cardiovascular or pulmonary disease
• Visual impairment
• Hearing loss

Sponsors & Collaborators

• Istanbul University: lead

Study Sites (1)

Istanbul University Istanbul Faculty of Medicine Department of Physical Medicine and Rehabilitation

Istanbul, Fatih, 34093, Turkey (Türkiye)

Location

MeSH Terms

Conditions

Parkinson Disease

Condition Hierarchy (Ancestors)

Parkinsonian Disorders; Basal Ganglia Diseases; Brain Diseases; Central Nervous System Diseases; Nervous System Diseases; Movement Disorders; Synucleinopathies; Neurodegenerative Diseases

Study Officials

• Ayse Yaliman, Prof

  Istanbul University Istanbul Faculty of Medicine Physical Medicine and Rehabilitation

  STUDY DIRECTOR

• Ekin Ilke Sen, MD

  Istanbul University Istanbul Faculty of Medicine Physical Medicine and Rehabilitation

  STUDY DIRECTOR

Study Design

• Study Type: interventional
• Phase: not applicable
• Allocation: RANDOMIZED
• Masking: TRIPLE
• Who Masked: CARE PROVIDER, INVESTIGATOR, OUTCOMES ASSESSOR
• Purpose: TREATMENT
• Intervention Model: PARALLEL
• Sponsor Type: OTHER
• Responsible Party: PRINCIPAL INVESTIGATOR
• PI Title: Assistant Doctor

Model Details: In this prospective, randomized, controlled, double-blinded study the patients were randomized to three groups as; dual-task group, single-task group and control group. All of the patients were scheduled on standard exercise programme. The patients in dual-task group received treadmill training with cognitive tasks and the patients in single-task group received treadmill training alone in addition to standard exercise programme. The training was scheduled as 30 minute sessions under supervision of a specialist, three times in a week for four weeks.

Study Record Dates

• First Submitted: April 3, 2019
• First Posted: April 4, 2019
• Study Start: October 1, 2018
• Primary Completion: March 1, 2019
• Study Completion: April 1, 2019
• Last Updated: April 5, 2019

Record last verified: 2019-04

Data Sharing

• IPD Sharing: Will not share

Locations

TU (1)