Effects of Motor Imagery on Motor Learning and Motor Retention in Octogenarian.

NCT04018196 | Terminated

• 2 other identifiers: 18CH1282018-A02365-50
• Study Type: interventional
• Target: 84
• Locations: 1 country
• Sites: 1

Brief Summary

Aging is associated with impairments in cognitive function, particularly motor learning and memorizing, impacting functional capacities. Older adults are still able to learn new skills but at a slower rate, and they forget quickly the new-learned skill because of an alteration in motor memory. Motor imagery, which is a mental simulation of an action without actual execution, has been demonstrated to improve performance in young adults and stabilize performance after a short break in older adults. However, in very old adults (\>80 years old) for whom the decline in motor and cognitive functions is greater, it is unknown whether motor imagery training during a short break is still efficient. Previous studies on old adults were performed on upper limb muscles. Because aging differentially affects upper and lower limb muscles, the present study will aim to explore the effects of motor imagery on motor memorizing in both upper and lower limb muscles.

Conditions

Aging

Keywords

Very old adults; Memorizing; Motor imagery; Motor learning; Upper limb; Lower limb; Motor task; Manual task

Outcome Measures

Primary Outcomes (1)

• Performance at the manual task (Nine Hole Peg Test (NHPT)) (s)

  Comparison of performance at the manual task (Nine Hole Peg Test (NHPT)) results in post-test between experimental and control group. Measured in seconds when performing manual task.

  Day: 0

Secondary Outcomes (5)

• Performance at the motor task (s)

  Day: 7

• Learning capacity of manual task (Nine Hole Peg Test (NHPT))

  Day: 0

• Learning capacity of motor task (hopscotch)

  Day: 7

• Test of 6 minutes walking (m)

  Day: 0

• Test of Get-up-and-Go (s)

  Day: 0

Study Arms (2)

Experimental group

EXPERIMENTAL

Patient aged over 80 years old will be included. They will have motor imagery training of manual task and motor imagery training of motor task.

Other: motor imagery as training manual task; Other: motor imagery as training motor task

Control group

ACTIVE COMPARATOR

Patient aged over 80 years old will be included. They will have emotionally neutral film as training of manual task and emotionally neutral film as training of motor task.

Other: emotionally neutral film as training of manual task; Other: emotionally neutral film as training of motor task

Interventions

motor imagery as training manual task OTHER

They will have a motor imagery as training manual task for 30 minutes. They will have 3 tests for performing manual task before training (pretest) and after training (post-test).

Also known as: Nine Hole Peg Test (NHPT)

Experimental group

motor imagery as training motor task OTHER

They will have a motor imagery as training motor task for 30 minutes before performing this task. They will have 3 tests for performing motor task before training (pretest) and after training (post-test).

Also known as: hopscotch

Experimental group

emotionally neutral film as training of manual task OTHER

They will have to watch an emotionally neutral as training manual task for 30 minutes before performing this task. They will have 3 tests for performing manual task before training (pretest) and after training (post-test).

Also known as: Nine Hole Peg Test (NHPT)

Control group

emotionally neutral film as training of motor task OTHER

They will have to watch an emotionally neutral as training motor task for 30 minutes before performing this task. They will have 3 tests for performing motor task before training (pretest) and after training (post-test).

Also known as: hopscotch

Control group

Eligibility Criteria

• Age: 80 Years+
• Sex: all
• Healthy Volunteers: No
• Age Groups: Older Adult (65+)

You may qualify if:

• Being part of the Proof cohort
• Signed written consent form
• Affiliated to social security

You may not qualify if:

• Pathology or chirurgical intervention causing locomotor disorder
• Neurological or psychic pathology
• Use psychotropic drugs
• Mini-Mental State Examination (MMSE) \< 20

Sponsors & Collaborators

• Centre Hospitalier Universitaire de Saint Etienne: lead

Study Sites (1)

CHU Saint-Etienne

Saint-Etienne, France

Location

MeSH Terms

Interventions

hop protein, Drosophila

Study Officials

• Léonard FEASSON, MD PhD

  CHU SAINT-ETIENNE

  PRINCIPAL INVESTIGATOR

Study Design

• Study Type: interventional
• Phase: not applicable
• Allocation: RANDOMIZED
• Masking: NONE
• Purpose: OTHER
• Intervention Model: PARALLEL
• Sponsor Type: OTHER
• Responsible Party: SPONSOR

Study Record Dates

• First Submitted: July 11, 2019
• First Posted: July 12, 2019
• Study Start: December 9, 2019
• Primary Completion: February 14, 2022
• Study Completion: February 15, 2022
• Last Updated: March 15, 2022

Record last verified: 2022-03

Data Sharing

• IPD Sharing: Will not share

Locations

FR (1)