Assessment of Carotid Artery Calcifications

NCT04017078 | Completed

• 1 other identifier: MCetin
• Study Type: observational
• Target: 1,101
• Locations: 1 country
• Sites: 1

Brief Summary

The aim of the study was to determine retrospectively the presence of carotid artery calcification (CAC) detected on digital panoramic radiographs (DPRs) and correlate the finding of such calcifications with gender, smoking status, medical history and periodontal status.The authors hypothesized that more CACs could observed in DPRs of individuals with periodontitis and CACs may correlate with the various risk factors included age, gender, smoking status, medical history.DPRs, periodontal status, medical (hypertension, diabetes, hyperlipidemia, cardiovascular disease) and smoking stories of 1101 patients (576 males, 525 females) were evaluated. The patients were divided into two groups as CAC detected in dental DPRs \[CAC(+)\] and those who were not \[CAC (-)\]. Periodontal status categorized as gingivitis, periodontitis and gingivitis with reduced periodontium.

Conditions

Carotid Artery Calcification; Periodontal Diseases

Keywords

carotid artery calcification; panoramic radiography; periodontitis; periodontal disease; systemic diseases

Outcome Measures

Primary Outcomes (1)

• prevalance of carotid artery calcifications

  Suspected CACs findings were defined as one or more radiopaque mass adjacent to the cervical vertebrae at or below the intervertebral space between C3 and C4 on the DPR.The CAC's were scored as present (+) or absent (-) by the dentomaxillofacial radiologist.

  The images were evaluated in two months.

Secondary Outcomes (5)

• The medical data of the patients with and without suspected CACs.

  Medical data was recorded in two months.

• Bleeding on probing (BOP)values of the patients with and without suspected CACs.

  BOP values were recorded in two months.

• Probing pocket depth (PPD) of the patients with and without suspected CACs.

  PPD values were recorded in two months.

• Clinical attachment level (CAL of the patients with and without suspected CACs.

  CAL values were recorded in two months.

• Periodontal status of the patients with andwithout suspected CACs.

  Periodontal status was recorded in two months.

Study Arms (1)

Patients who referred for periodontal therapy

Patients who referred to Baskent University, Faculty of Dentistry, Department of Periodontology, during 2016-2018

Other: diagnosis of carotid artery calcification on digital panoramic radiograph

Interventions

diagnosis of carotid artery calcification on digital panoramic radiograph OTHER

Suspected carotid arty calcifications findings were defined as one or more radiopaque mass adjacent to the cervical vertebrae at or below the intervertebral space between C3 and C4 on the DPR.

Patients who referred for periodontal therapy

Eligibility Criteria

• Age: 14 Years - 86 Years
• Sex: all
• Healthy Volunteers: No
• Age Groups: Child (0-17), Adult (18-64), Older Adult (65+)
• Sampling Method: Probability Sample

Study Population

Baskent University, Faculty of Dentistry, Department of Periodontology

You may qualify if:

• All patients referred to Baskent University, Faculty of Dentistry, Department of Periodontology, during 2016-2018

You may not qualify if:

• Subjects with the lack of medical data
• DPRs not showing vertebra C3 and C4 were excluded.

Sponsors & Collaborators

• Baskent University: lead

Study Sites (1)

Department of Periodontology, Faculty of Dentistry, Baskent University

Ankara, 06790, Turkey (Türkiye)

Location

Related Publications (1)

• Bilgin Cetin M, Sezgin Y, Nisanci Yilmaz MN, Koseoglu Secgin C. Assessment of carotid artery calcifications on digital panoramic radiographs and their relationship with periodontal condition and cardiovascular risk factors. Int Dent J. 2020 Sep 29;71(2):160-6. doi: 10.1111/idj.12618. Online ahead of print.

  PMID: 32996164 DERIVED

MeSH Terms

Conditions

Periodontal Diseases; Periodontitis

Condition Hierarchy (Ancestors)

Mouth Diseases; Stomatognathic Diseases

Study Officials

• Mehtap Bilgin Çetin, DDS,PhD

  Department of Periodontology, Faculty of Dentistry, Baskent University

  PRINCIPAL INVESTIGATOR

Study Design

• Study Type: observational
• Observational Model: OTHER
• Time Perspective: CROSS SECTIONAL
• Sponsor Type: OTHER
• Responsible Party: PRINCIPAL INVESTIGATOR
• PI Title: Assosc.Prof.Ph.D

Study Record Dates

• First Submitted: June 27, 2019
• First Posted: July 12, 2019
• Study Start: September 1, 2018
• Primary Completion: September 25, 2018
• Study Completion: October 1, 2018
• Last Updated: July 12, 2019

Record last verified: 2019-07

Data Sharing

• IPD Sharing: Will not share

Locations

TU (1)