Exergaming Improves Executive Functions in Patients With Metabolic Syndrome

NCT04015583 | Completed

• 1 other identifier: KosinUGH
• Study Type: interventional
• Target: 22
• Locations: 1 country
• Sites: 1

Brief Summary

Background: Recent studies indicate that exercise-related games can improve executive function, attention processing, and visuospatial skills. Objective: This study investigates whether exercise with exergaming can improve the executive function in patients with metabolic syndrome (MetS). Methods: Twenty-two MetS patients were recruited and randomly assigned to the exergaming group (EXG) and treadmill exercise group (TEG). The reaction time (RT) and electrophysiological signal from the frontal (Fz), central (Cz), and parietal (Pz) cortex were collected during a Stroop task after 12 weeks' exercise.

Conditions

Executive Functions; Metabolic Syndrome; Aerobic Exercise

Keywords

exergaming; executive functions; event-related potential; metabolic syndrome

Outcome Measures

Primary Outcomes (1)

• Change of amplitude of N200 as measured by Electroencephalographic

  N200 negativity (200\~350 ms post-stimulus) is an event-related potential, which indicates attentional capacity that is usually induced before motion response control and is related to the cognitive processes of stimulus recognition and differentiationcontrol) are a set of cognitive processes that are necessary for the cognitive control of behavior

  Change from Baseline N200 at 3 months

Secondary Outcomes (1)

• Change of amplitude of P300 as measured by Electroencephalographic

  Change from Baseline P300 at 3 months

Study Arms (2)

exergaming group

EXPERIMENTAL

The exergaming group (EXG) performed exercise using Exerheart® devices (D\&J Humancare, Busan, South Korea) composed of a running/jumping mat \[730(W) × 730(D) × 130(H)\] and a tablet PC on a stand (can be adjusted to any height between 70 and 155 cm) (Supplemental Figure 1A). Exerheart® is an exergaming developed for in-situ running along with the video game called "Alchemist's Treasure" (D\&J Humancare, Busan, South Korea). To play this game, the subject has to run or jump on a spot on the mat to move a virtual avatar on the screen of the tablet PC to the front, back, left, and right along with music. The subject can control the speed of avatar movement by running or jumping speed on the mat.

Behavioral: exergaming group

treadmill exercise group

ACTIVE COMPARATOR

The treadmill exercise group (TEG) performed exercise using commercial treadmills (MOTUS, Gyeonggi-do, South Korea). Each subject walked or ran on the treadmill at a comfortable speed.

Behavioral: exergaming group

Interventions

exergaming group BEHAVIORAL

Exergame is 'exercise + game'. Treadmill exercise is traiditional aerobic exercise

Also known as: treadmill exercise group

exergaming group; treadmill exercise group

Eligibility Criteria

• Age: 50 Years - 80 Years
• Sex: all
• Healthy Volunteers: No
• Age Groups: Adult (18-64), Older Adult (65+)

You may qualify if:

• Metabolic syndrome patients(NCEP-ATP III)

You may not qualify if:

• Neurologic disorders
• Malignant disease
• Renal failure
• Chronic obstructive pulmonary disease
• Valvular heart disease
• Acute coronary syndrome
• Myocardial infarction
• Musculoskeletal patients

Sponsors & Collaborators

• Kyoung Im Cho: lead

Study Sites (1)

Kosin University Gospel Hospital

Busan, 49267, South Korea

Location

Related Publications (2)

• Baranowski T, Abdelsamad D, Baranowski J, O'Connor TM, Thompson D, Barnett A, Cerin E, Chen TA. Impact of an active video game on healthy children's physical activity. Pediatrics. 2012 Mar;129(3):e636-42. doi: 10.1542/peds.2011-2050. Epub 2012 Feb 27.

  PMID: 22371457 BACKGROUND

• Wu S, Jo EA, Ji H, Kim KH, Park JJ, Kim BH, Cho KI. Exergaming Improves Executive Functions in Patients With Metabolic Syndrome: Randomized Controlled Trial. JMIR Serious Games. 2019 Jul 31;7(3):e13575. doi: 10.2196/13575.

  PMID: 31368441 DERIVED

MeSH Terms

Conditions

Metabolic Syndrome

Condition Hierarchy (Ancestors)

Insulin Resistance; Hyperinsulinism; Glucose Metabolism Disorders; Metabolic Diseases; Nutritional and Metabolic Diseases

Study Officials

• Kyoungim Cho, MD, PhD

  Kosin University Gospel Hospital

  PRINCIPAL INVESTIGATOR

Study Design

• Study Type: interventional
• Phase: not applicable
• Allocation: RANDOMIZED
• Masking: NONE
• Purpose: PREVENTION
• Intervention Model: PARALLEL
• Sponsor Type: OTHER
• Responsible Party: SPONSOR INVESTIGATOR
• PI Title: Clinical Professor

Model Details: exergaming group and treadmill exercise group

Study Record Dates

• First Submitted: June 27, 2019
• First Posted: July 11, 2019
• Study Start: April 1, 2017
• Primary Completion: December 31, 2017
• Study Completion: March 31, 2018
• Last Updated: July 11, 2019

Record last verified: 2019-07

Data Sharing

• IPD Sharing: Will not share

Locations

KR (1)