NCT03300271

Brief Summary

The purpose of this randomized study is to assess the efficacy of a mobile application for the improvement of blood pressure and insulin resistance in people with metabolic abnormalities.

Trial Health

87
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
129

participants targeted

Target at P50-P75 for not_applicable

Timeline
Completed

Started Oct 2017

Shorter than P25 for not_applicable

Geographic Reach
1 country

1 active site

Status
completed

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

First Submitted

Initial submission to the registry

September 24, 2017

Completed
9 days until next milestone

First Posted

Study publicly available on registry

October 3, 2017

Completed
25 days until next milestone

Study Start

First participant enrolled

October 28, 2017

Completed
9 months until next milestone

Primary Completion

Last participant's last visit for primary outcome

August 2, 2018

Completed
Same day until next milestone

Study Completion

Last participant's last visit for all outcomes

August 2, 2018

Completed
Last Updated

January 11, 2019

Status Verified

January 1, 2019

Enrollment Period

9 months

First QC Date

September 24, 2017

Last Update Submit

January 9, 2019

Conditions

Outcome Measures

Primary Outcomes (1)

  • Change in systolic/diastolic blood pressures

    Change of systolic/diastolic blood pressures and insulin resistance are the differences between the last visit and baseline (screening visit).

    24 weeks

Secondary Outcomes (1)

  • Change in the eligibility criteria for metabolic syndrome

    24 weeks

Study Arms (3)

No intervention (Education)

OTHER

Participants in this group is provided education. Education includes information of metabolic syndrome, methods to manage lifestyle (diet, physical activity).

Other: Education

Mobile Application (Self monitoring)

EXPERIMENTAL

Participants in this group will be introduced to use a mobile application to self record and monitor their life style behaviors. They will be also be provided education same as the control group.

Other: Mobile application for self monitoring

Mobile Application (Personal coaching)

EXPERIMENTAL

Participants in this group will be introduced to use a mobile application. Personal coaches such as dietitian, sports manager encourage to improve their life style behaviors. They will be also be provided education same as the control group.

Other: Mobile application for personal coaching

Interventions

Participants in this group will be introduced to use a mobile application to self record and monitor their life style behaviors. They will be also be provided education same as the control group.

Mobile Application (Self monitoring)

Participants in this group is provided education. Education includes information of metabolic syndrome, methods to manage lifestyle (diet, physical activity).

No intervention (Education)

Participants in this group will be introduced to use a mobile application. Personal coaches such as dietitian, sports manager encourage to improve their life style behaviors. They will be also be provided education same as the control group.

Mobile Application (Personal coaching)

Eligibility Criteria

Age30 Years - 59 Years
Sexall
Healthy VolunteersYes
Age GroupsAdult (18-64)

You may qualify if:

  • "Etiologic study on cardiovascular and metabolic diseases: prospective cohort study (Severance Hospital IRB No. 4-2013-0661)" participants
  • Smartphone user
  • Metabolic abnormality. Having 2 or more components of metabolic syndrome described below:
  • Central obesity : waist circumference ≥ 90cm in male, ≥ 80cm in female
  • Systolic/diastolic blood pressure ≥ 130/85 mmHg
  • Serum triglyceride ≥ 150 mg/dL
  • Serum high density lipoprotein cholesterol \< 40 mg/dL in male, 50 mg/dL in female
  • Fasting glucose ≥ 100mg/dL

You may not qualify if:

  • Presently or planning for pregnant/breastfeeding during the study. Or confirmed pregnancy by a urine test.
  • Currently taking medication (including insulin injection) for hypertension, dyslipidemia, or diabetes.
  • Presently using a mobile application for lifestyle modification

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

Yonsei University College of Medicine

Seoul, 03722, South Korea

Location

Related Publications (1)

  • Cho SMJ, Lee JH, Shim JS, Yeom H, Lee SJ, Jeon YW, Kim HC. Effect of Smartphone-Based Lifestyle Coaching App on Community-Dwelling Population With Moderate Metabolic Abnormalities: Randomized Controlled Trial. J Med Internet Res. 2020 Oct 9;22(10):e17435. doi: 10.2196/17435.

MeSH Terms

Conditions

Metabolic Syndrome

Interventions

Educational Status

Condition Hierarchy (Ancestors)

Insulin ResistanceHyperinsulinismGlucose Metabolism DisordersMetabolic DiseasesNutritional and Metabolic Diseases

Intervention Hierarchy (Ancestors)

Socioeconomic FactorsPopulation Characteristics

Study Design

Study Type
interventional
Phase
not applicable
Allocation
RANDOMIZED
Masking
DOUBLE
Who Masked
INVESTIGATOR, OUTCOMES ASSESSOR
Masking Details
A designated researcher will be responsible for the random allocation and mask the results, so the investigators and the outcomes assessor do know the which group the participants are been allocated in.
Purpose
PREVENTION
Intervention Model
PARALLEL
Model Details: Participants will be randomly assigned to either the experimental conditions (mobile application), or the usual condition (education).
Sponsor Type
OTHER
Responsible Party
SPONSOR

Study Record Dates

First Submitted

September 24, 2017

First Posted

October 3, 2017

Study Start

October 28, 2017

Primary Completion

August 2, 2018

Study Completion

August 2, 2018

Last Updated

January 11, 2019

Record last verified: 2019-01

Data Sharing

IPD Sharing
Will not share

Locations